39 items (Alligator sinensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APC	Adenomatous polyposis coli protein isoform X1. (2849 aa)
	VCPIP1	Deubiquitinating protein VCIP135. (1164 aa)
	OTUD3	OTU domain-containing protein 3 isoform X1. (347 aa)
	TRAF6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (545 aa)
	RPS27A	ubiquitin-40S ribosomal protein S27a. (156 aa)
	GUF1	Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. (632 aa)
	TNIP3	TNFAIP3-interacting protein 3 isoform X1. (408 aa)
	UBC	polyubiquitin-C. (381 aa)
	TRAF3	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (567 aa)
	OTUD4	OTU domain-containing protein 4 isoform X1. (1109 aa)
	TRAF5	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (557 aa)
	ZRANB1	LOW QUALITY PROTEIN: ubiquitin thioesterase ZRANB1. (714 aa)
	CDK1	LOW QUALITY PROTEIN: cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (311 aa)
	RNF167	E3 ubiquitin-protein ligase RNF167 isoform X1. (329 aa)
	OTUD7B	OTU domain-containing protein 7B. (866 aa)
	OTUD5	OTU domain-containing protein 5. (344 aa)
	KXD1	kxDL motif-containing protein 1. (176 aa)
	TNFAIP3	Tumor necrosis factor alpha-induced protein 3 isoform X1. (817 aa)
	SPATA5L1	Spermatogenesis-associated protein 5-like protein 1; Belongs to the AAA ATPase family. (628 aa)
	OTUB1	Ubiquitin thioesterase OTUB1. (224 aa)
	UBB	polyubiquitin-B. (233 aa)
	NOD1	Nucleotide-binding oligomerization domain-containing protein 1 isoform X1. (951 aa)
	LOC102374037	RING finger protein 148-like. (352 aa)
	TNIP2	TNFAIP3-interacting protein 2. (348 aa)
	LOC102369010	E3 ubiquitin-protein ligase RNF13 isoform X1. (246 aa)
	UBA52	ubiquitin-60S ribosomal protein L40. (104 aa)
	RIPK1	Receptor-interacting serine/threonine-protein kinase 1 isoform X1. (711 aa)
	LOC102374028	E3 ubiquitin-protein ligase RNF13-like. (183 aa)
	RNF128	E3 ubiquitin-protein ligase RNF128 isoform X1. (419 aa)
	TP53	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (397 aa)
	APC2	LOW QUALITY PROTEIN: adenomatous polyposis coli protein 2. (2427 aa)
	LOC112549194	LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF167-like. (381 aa)
	ZNRF4	E3 ubiquitin-protein ligase ZNRF4. (302 aa)
	OTUD7A	OTU domain-containing protein 7A. (934 aa)
	TNIP1	TNFAIP3-interacting protein 1. (524 aa)
	YOD1	Ubiquitin thioesterase OTU1. (265 aa)
	ESR1	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (627 aa)
	SPATA5	Spermatogenesis-associated protein 5 isoform X1. (831 aa)
	VCP	Transitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family. (761 aa)

Your Current Organism:

Alligator sinensis

NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APC	APC2	A0A3Q0GXG2	A0A3Q0FXN0	Adenomatous polyposis coli protein isoform X1.	LOW QUALITY PROTEIN: adenomatous polyposis coli protein 2.	0.900
APC	OTUD7A	A0A3Q0GXG2	A0A3Q0G6E2	Adenomatous polyposis coli protein isoform X1.	OTU domain-containing protein 7A.	0.444
APC	OTUD7B	A0A3Q0GXG2	A0A1U7S9B4	Adenomatous polyposis coli protein isoform X1.	OTU domain-containing protein 7B.	0.444
APC	TNFAIP3	A0A3Q0GXG2	A0A1U7SGZ2	Adenomatous polyposis coli protein isoform X1.	Tumor necrosis factor alpha-induced protein 3 isoform X1.	0.444
APC	UBB	A0A3Q0GXG2	A0A3Q0HJE8	Adenomatous polyposis coli protein isoform X1.	polyubiquitin-B.	0.521
APC	UBC	A0A3Q0GXG2	A0A1U7RLK0	Adenomatous polyposis coli protein isoform X1.	polyubiquitin-C.	0.499
APC	VCPIP1	A0A3Q0GXG2	A0A3Q0H2R8	Adenomatous polyposis coli protein isoform X1.	Deubiquitinating protein VCIP135.	0.444
APC	ZRANB1	A0A3Q0GXG2	A0A1U7RZI9	Adenomatous polyposis coli protein isoform X1.	LOW QUALITY PROTEIN: ubiquitin thioesterase ZRANB1.	0.648
APC2	APC	A0A3Q0FXN0	A0A3Q0GXG2	LOW QUALITY PROTEIN: adenomatous polyposis coli protein 2.	Adenomatous polyposis coli protein isoform X1.	0.900
APC2	OTUD7A	A0A3Q0FXN0	A0A3Q0G6E2	LOW QUALITY PROTEIN: adenomatous polyposis coli protein 2.	OTU domain-containing protein 7A.	0.444
APC2	OTUD7B	A0A3Q0FXN0	A0A1U7S9B4	LOW QUALITY PROTEIN: adenomatous polyposis coli protein 2.	OTU domain-containing protein 7B.	0.444
APC2	TNFAIP3	A0A3Q0FXN0	A0A1U7SGZ2	LOW QUALITY PROTEIN: adenomatous polyposis coli protein 2.	Tumor necrosis factor alpha-induced protein 3 isoform X1.	0.444
APC2	UBB	A0A3Q0FXN0	A0A3Q0HJE8	LOW QUALITY PROTEIN: adenomatous polyposis coli protein 2.	polyubiquitin-B.	0.521
APC2	UBC	A0A3Q0FXN0	A0A1U7RLK0	LOW QUALITY PROTEIN: adenomatous polyposis coli protein 2.	polyubiquitin-C.	0.499
APC2	VCPIP1	A0A3Q0FXN0	A0A3Q0H2R8	LOW QUALITY PROTEIN: adenomatous polyposis coli protein 2.	Deubiquitinating protein VCIP135.	0.444
APC2	ZRANB1	A0A3Q0FXN0	A0A1U7RZI9	LOW QUALITY PROTEIN: adenomatous polyposis coli protein 2.	LOW QUALITY PROTEIN: ubiquitin thioesterase ZRANB1.	0.648
CDK1	RPS27A	A0A1U7S0R9	A0A1U7RD94	LOW QUALITY PROTEIN: cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	ubiquitin-40S ribosomal protein S27a.	0.673
CDK1	TP53	A0A1U7S0R9	A0A3Q0FUE5	LOW QUALITY PROTEIN: cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.758
CDK1	UBA52	A0A1U7S0R9	A0A1U8DBX4	LOW QUALITY PROTEIN: cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	ubiquitin-60S ribosomal protein L40.	0.661
CDK1	UBB	A0A1U7S0R9	A0A3Q0HJE8	LOW QUALITY PROTEIN: cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	polyubiquitin-B.	0.638