81 items (Alligator sinensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	KRT18	Keratin, type I cytoskeletal 18; Belongs to the intermediate filament family. (434 aa)
	LOC102373494	Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (406 aa)
	LOC102371330	Keratin, type II cytoskeletal cochleal-like; Belongs to the intermediate filament family. (502 aa)
	LOC102373665	Keratin, type II cytoskeletal 1-like; Belongs to the intermediate filament family. (474 aa)
	LOC102368806	Keratin, type I cytoskeletal 13-like; Belongs to the intermediate filament family. (574 aa)
	LOC102372665	Keratin, type II cytoskeletal 6A; Belongs to the intermediate filament family. (633 aa)
	LOC102377836	Keratin, type II cytoskeletal cochleal-like; Belongs to the intermediate filament family. (548 aa)
	PKP2	Plakophilin-2 isoform X1. (780 aa)
	EVPL	Envoplakin isoform X1. (2025 aa)
	PKP1	Plakophilin-1 isoform X1. (732 aa)
	LOC102386635	chymotrypsin-C-like; Belongs to the peptidase S1 family. (266 aa)
	LOC102386393	chymotrypsin-C-like; Belongs to the peptidase S1 family. (281 aa)
	LOC102384740	Chymotrypsin-like elastase family member 2A; Belongs to the peptidase S1 family. (279 aa)
	LOC102369323	Keratin, type I cytoskeletal 9-like isoform X1; Belongs to the intermediate filament family. (578 aa)
	LOC102386889	Chymotrypsin-like elastase family member 2A; Belongs to the peptidase S1 family. (281 aa)
	LOC102379508	Keratin, type I cytoskeletal 10-like; Belongs to the intermediate filament family. (853 aa)
	LOC102372247	LOW QUALITY PROTEIN: uncharacterized protein LOC102372247; Belongs to the intermediate filament family. (1222 aa)
	LOC102369067	Keratin, type I cytoskeletal 13-like; Belongs to the intermediate filament family. (533 aa)
	LOC102387714	Serine protease inhibitor Kazal-type 5-like isoform X1. (139 aa)
	LOC102388130	Serine protease inhibitor Kazal-type 5. (338 aa)
	LOC102368725	Ovoinhibitor-like. (552 aa)
	LOC102367915	LOW QUALITY PROTEIN: desmoglein-1-like; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1102 aa)
	LOC102385059	Suppressor of tumorigenicity 14 protein-like. (817 aa)
	LOC102372666	Keratin, type I cytoskeletal 19-like isoform X1; Belongs to the intermediate filament family. (448 aa)
	LOC102384487	chymotrypsin-C-like; Belongs to the peptidase S1 family. (266 aa)
	LOC102386144	chymotrypsin-C-like; Belongs to the peptidase S1 family. (283 aa)
	LOC102375716	Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (403 aa)
	LOC102378366	Keratin, type I cytoskeletal 24; Belongs to the intermediate filament family. (471 aa)
	LOC102376692	Keratin, type I cuticular Ha6-like; Belongs to the intermediate filament family. (449 aa)
	LOC102378129	Keratin, type I cytoskeletal 10; Belongs to the intermediate filament family. (396 aa)
	LOC102376455	LOW QUALITY PROTEIN: keratin, type I cytoskeletal 15-like; Belongs to the intermediate filament family. (348 aa)
	KAZN	Kazrin isoform X2. (632 aa)
	LOC102372191	Protein-glutamine gamma-glutamyltransferase 5-like. (724 aa)
	LOC106722579	Keratin, type II cytoskeletal 4-like; Belongs to the intermediate filament family. (570 aa)
	LOC106722558	P53 apoptosis effector related to PMP-22-like. (118 aa)
	JUP	Junction plakoglobin. (743 aa)
	LOC102380036	Keratin, type II cytoskeletal 5-like; Belongs to the intermediate filament family. (663 aa)
	PKP4	Plakophilin-4 isoform X1. (1210 aa)
	LOC102374496	Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (404 aa)
	ARMC2	Armadillo repeat-containing protein 2 isoform X1. (878 aa)
	LOC102374246	Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (394 aa)
	LOC112551217	Elastase-1-like. (334 aa)
	LOC102378082	Keratin, type II cytoskeletal 5-like; Belongs to the intermediate filament family. (672 aa)
	LOC102376217	Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (395 aa)
	LOC102367973	Keratin, type I cytoskeletal 14-like; Belongs to the intermediate filament family. (490 aa)
	LOC102369678	Keratin, type I cytoskeletal 17-like; Belongs to the intermediate filament family. (490 aa)
	LOC102373245	Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (403 aa)
	KRT8	Keratin, type II cytoskeletal 8; Belongs to the intermediate filament family. (480 aa)
	LOC102379785	Keratin, type II cytoskeletal 8-like; Belongs to the intermediate filament family. (452 aa)
	LOC102371761	Keratin, type II cytoskeletal 6A; Belongs to the intermediate filament family. (519 aa)
	LOC102377597	Keratin, type II cytoskeletal cochleal; Belongs to the intermediate filament family. (525 aa)
	PPL	Periplakin. (1763 aa)
	LOC102385731	Desmocollin-1 isoform X1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (893 aa)
	TMEM47	Transmembrane protein 47. (163 aa)
	LOC102385021	Keratin, type I cytoskeletal 15-like isoform X1; Belongs to the intermediate filament family. (483 aa)
	LOC102377411	Keratin, type I cytoskeletal 23; Belongs to the intermediate filament family. (518 aa)
	PERP	P53 apoptosis effector related to PMP-22. (189 aa)
	KRT20	Keratin, type I cytoskeletal 20; Belongs to the intermediate filament family. (439 aa)
	LOC102377886	Keratin, type I cytoskeletal 12; Belongs to the intermediate filament family. (524 aa)
	LOC102384765	Keratin, type I cytoskeletal 19; Belongs to the intermediate filament family. (422 aa)
	LOC102373165	Keratin, type I cytoskeletal 10-like; Belongs to the intermediate filament family. (447 aa)
	LOC102368169	Desmoglein-2. (1159 aa)
	CTNND2	Catenin delta-2. (1167 aa)
	ST14	Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix. (842 aa)
	LOC102380041	Keratin, type II cytoskeletal 6C-like; Belongs to the intermediate filament family. (650 aa)
	LOC102379545	Keratin, type II cytoskeletal 3-like; Belongs to the intermediate filament family. (653 aa)
	LOC102377177	Keratin, type I cuticular Ha6-like; Belongs to the intermediate filament family. (355 aa)
	LOC102373062	Elastase-1-like; Belongs to the peptidase S1 family. (253 aa)
	LOC102373744	Lipase member M-like. (302 aa)
	LOC102376960	Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (396 aa)
	PKP3	Plakophilin-3. (833 aa)
	LOC102379592	Serine protease inhibitor Kazal-type 6-like. (84 aa)
	KRT222	Keratin-like protein KRT222; Belongs to the intermediate filament family. (281 aa)
	KRT80	Keratin, type II cytoskeletal 80; Belongs to the intermediate filament family. (570 aa)
	LOC102371667	Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (398 aa)
	LOC102374000	Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (396 aa)
	LOC102375971	Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (403 aa)
	LOC102368390	Keratin, type I cytoskeletal 14-like; Belongs to the intermediate filament family. (495 aa)
	LOC102384514	Keratin, type I cytoskeletal 19-like; Belongs to the intermediate filament family. (463 aa)
	LOC102376945	Keratin, type I cuticular Ha5-like; Belongs to the intermediate filament family. (344 aa)
	LOC102372642	Transmembrane protein 47-like. (172 aa)

Your Current Organism:

Alligator sinensis

NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARMC2	JUP	A0A3Q0H6D3	A0A1U8DEU3	Armadillo repeat-containing protein 2 isoform X1.	Junction plakoglobin.	0.409
CTNND2	JUP	A0A3Q0HHK6	A0A1U8DEU3	Catenin delta-2.	Junction plakoglobin.	0.718
CTNND2	LOC102367915	A0A3Q0HHK6	A0A3Q0HDE6	Catenin delta-2.	LOW QUALITY PROTEIN: desmoglein-1-like; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	0.488
CTNND2	LOC102368169	A0A3Q0HHK6	A0A3Q0HHR7	Catenin delta-2.	Desmoglein-2.	0.488
CTNND2	LOC102385731	A0A3Q0HHK6	A0A1U7RAH9	Catenin delta-2.	Desmocollin-1 isoform X1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	0.621
CTNND2	LOC106722558	A0A3Q0HHK6	A0A1U8DMN7	Catenin delta-2.	P53 apoptosis effector related to PMP-22-like.	0.458
CTNND2	PERP	A0A3Q0HHK6	A0A1U7RIN3	Catenin delta-2.	P53 apoptosis effector related to PMP-22.	0.458
EVPL	JUP	A0A1U8CUM2	A0A1U8DEU3	Envoplakin isoform X1.	Junction plakoglobin.	0.497
EVPL	KAZN	A0A1U8CUM2	A0A3Q0G6Z8	Envoplakin isoform X1.	Kazrin isoform X2.	0.670
EVPL	LOC102385731	A0A1U8CUM2	A0A1U7RAH9	Envoplakin isoform X1.	Desmocollin-1 isoform X1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	0.497
EVPL	PKP1	A0A1U8CUM2	A0A1U7SXH2	Envoplakin isoform X1.	Plakophilin-1 isoform X1.	0.576
EVPL	PKP2	A0A1U8CUM2	A0A1U8D0U3	Envoplakin isoform X1.	Plakophilin-2 isoform X1.	0.482
JUP	ARMC2	A0A1U8DEU3	A0A3Q0H6D3	Junction plakoglobin.	Armadillo repeat-containing protein 2 isoform X1.	0.409
JUP	CTNND2	A0A1U8DEU3	A0A3Q0HHK6	Junction plakoglobin.	Catenin delta-2.	0.718
JUP	EVPL	A0A1U8DEU3	A0A1U8CUM2	Junction plakoglobin.	Envoplakin isoform X1.	0.497
JUP	LOC102367915	A0A1U8DEU3	A0A3Q0HDE6	Junction plakoglobin.	LOW QUALITY PROTEIN: desmoglein-1-like; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	0.737
JUP	LOC102368169	A0A1U8DEU3	A0A3Q0HHR7	Junction plakoglobin.	Desmoglein-2.	0.737
JUP	LOC102372247	A0A1U8DEU3	A0A1U7SJS6	Junction plakoglobin.	LOW QUALITY PROTEIN: uncharacterized protein LOC102372247; Belongs to the intermediate filament family.	0.470
JUP	LOC102384765	A0A1U8DEU3	A0A1U7RR64	Junction plakoglobin.	Keratin, type I cytoskeletal 19; Belongs to the intermediate filament family.	0.415
JUP	LOC102385731	A0A1U8DEU3	A0A1U7RAH9	Junction plakoglobin.	Desmocollin-1 isoform X1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	0.863