STRINGSTRING
GNGT2 GNGT2 ZNF217 ZNF217 TRPS1 TRPS1 HSP90AA1 HSP90AA1 ZDHHC7 ZDHHC7 GREB1L GREB1L LOC102384030 LOC102384030 CAV3 CAV3 PIK3R1 PIK3R1 CSDE1 CSDE1 CREBBP CREBBP ELK1 ELK1 YY1 YY1 LOC102387236 LOC102387236 POLR2G POLR2G KDM1A KDM1A LOC102380682 LOC102380682 GTF2F2 GTF2F2 PTGES3 PTGES3 NCOA3 NCOA3 PDPK1 PDPK1 UHMK1 UHMK1 POLR2A POLR2A PRMT1 PRMT1 GTF2A1 GTF2A1 PIK3CA PIK3CA DDX5 DDX5 GNB4 GNB4 BTC BTC CBFB CBFB STRN STRN EREG EREG EPGN EPGN TGFA TGFA ZC3H12C ZC3H12C POLR2J POLR2J NCOA2 NCOA2 LOC102370064 LOC102370064 GTF2A2 GTF2A2 FOXA2 FOXA2 STRN3 STRN3 FOXA1 FOXA1 GREB1 GREB1 AKT3 AKT3 GTF2A1L GTF2A1L CAV1 CAV1 CARM1 CARM1 KANK1 KANK1 GNG2 GNG2 KANK2 KANK2 ESR1 ESR1 CAV2 CAV2 CXXC5 CXXC5 EGF EGF LOC102387438 LOC102387438 KANK3 KANK3 LOC112550695 LOC112550695 HBEGF HBEGF CITED1 CITED1 LOC102380057 LOC102380057 KRAS KRAS LOC102385776 LOC102385776 PRMT8 PRMT8 POLR2B POLR2B PGR PGR NCOA1 NCOA1 POLR2D POLR2D GNG5 GNG5 GNB1 GNB1 GATA3 GATA3 MYB MYB POLR2I POLR2I LOC102374839 LOC102374839 GNG4 GNG4 STRN4 STRN4 USF1 USF1 LOC102383253 LOC102383253 POLR2H POLR2H XPO1 XPO1 LOC102384725 LOC102384725 HRAS HRAS LOC102373634 LOC102373634 LOC102388444 LOC102388444 AREG AREG TBPL2 TBPL2 LOC112547860 LOC112547860 WDR64 WDR64 LOC102383137 LOC102383137 GNG13 GNG13 CDK9 CDK9 GTF2F1 GTF2F1 POLR2L POLR2L LOC102382262 LOC102382262 HSP90AB1 HSP90AB1 POLR2E POLR2E TBP TBP USF2 USF2 LOC102379984 LOC102379984 LOC102383903 LOC102383903 TBPL1 TBPL1 AKT1 AKT1 POLR2C POLR2C ZC3H12A ZC3H12A ZDHHC21 ZDHHC21 MMP7 MMP7 NRAS NRAS AKT2 AKT2 LOC102384812 LOC102384812 CREB1 CREB1 LOC102373170 LOC102373170 FKBP4 FKBP4 POLR2K POLR2K PIK3R2 PIK3R2 EBAG9 EBAG9 HSPB1 HSPB1 KANK4 KANK4 LOC102372061 LOC102372061 MMP9 MMP9 LOC102385431 LOC102385431 ZC3H12B ZC3H12B PPID PPID LOC102384519 LOC102384519 NRIP1 NRIP1 EP300 EP300 LOC102379915 LOC102379915 CCNT1 CCNT1 LOC102387686 LOC102387686 LOC102385673 LOC102385673 POLR2F POLR2F LOC102374986 LOC102374986 FKBP5 FKBP5 ESR2 ESR2 S1PR3 S1PR3
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
ZNF217Zinc finger protein 217. (1073 aa)
TRPS1Zinc finger transcription factor Trps1 isoform X1. (1294 aa)
HSP90AA1Heat shock protein HSP 90-alpha. (728 aa)
ZDHHC7Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (305 aa)
GREB1LLOW QUALITY PROTEIN: GREB1-like protein. (1966 aa)
LOC102384030Histone H2B; Belongs to the histone H2B family. (126 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (843 aa)
CREBBPCREB-binding protein. (2468 aa)
ELK1ETS domain-containing protein Elk-1 isoform X1. (396 aa)
YY1Transcriptional repressor protein YY1. (212 aa)
LOC102387236Endoribonuclease ZC3H12A. (523 aa)
POLR2GDNA-directed RNA polymerase II subunit RPB7. (170 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (751 aa)
LOC102380682Vegetative cell wall protein gp1-like. (393 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (268 aa)
PTGES3Prostaglandin E synthase 3. (179 aa)
NCOA3Nuclear receptor coactivator. (1438 aa)
PDPK13-phosphoinositide-dependent protein kinase 1 isoform X2. (701 aa)
UHMK1Serine/threonine-protein kinase Kist isoform X1. (366 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1960 aa)
PRMT1Protein arginine N-methyltransferase 1 isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (365 aa)
GTF2A1Transcription initiation factor IIA subunit 1 isoform X1. (401 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
DDX5Probable ATP-dependent RNA helicase DDX5; Belongs to the DEAD box helicase family. (611 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4. (340 aa)
BTCProbetacellulin. (175 aa)
CBFBCore-binding factor subunit beta isoform X1. (211 aa)
STRNStriatin isoform X1. (706 aa)
EREGProepiregulin. (173 aa)
EPGNEpigen isoform X1. (171 aa)
TGFAProtransforming growth factor alpha isoform X1. (190 aa)
ZC3H12CProbable ribonuclease ZC3H12C isoform X1. (920 aa)
POLR2JDNA-directed RNA polymerase II subunit RPB11-a. (114 aa)
NCOA2Nuclear receptor coactivator. (1462 aa)
LOC102370064alanyl-tRNA editing protein Aarsd1. (575 aa)
GTF2A2Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa)
FOXA2LOW QUALITY PROTEIN: hepatocyte nuclear factor 3-beta. (321 aa)
STRN3Striatin-3. (712 aa)
FOXA1Hepatocyte nuclear factor 3-alpha. (190 aa)
GREB1Protein GREB1. (1951 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa)
GTF2A1LTFIIA-alpha and beta-like factor. (441 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (128 aa)
CARM1Histone-arginine methyltransferase CARM1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (548 aa)
KANK1KN motif and ankyrin repeat domain-containing protein 1 isoform X1. (1366 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (93 aa)
KANK2KN motif and ankyrin repeat domain-containing protein 2 isoform X1. (844 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (627 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (153 aa)
CXXC5CXXC-type zinc finger protein 5 isoform X1. (303 aa)
EGFPro-epidermal growth factor. (1257 aa)
LOC102387438Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (442 aa)
KANK3LOW QUALITY PROTEIN: KN motif and ankyrin repeat domain-containing protein 3. (1039 aa)
LOC112550695Phosphatidylinositol 3-kinase regulatory subunit alpha-like. (322 aa)
HBEGFProheparin-binding EGF-like growth factor. (200 aa)
CITED1Cbp/p300-interacting transactivator 1. (220 aa)
LOC102380057Phosphatidylinositol 3-kinase regulatory subunit gamma. (419 aa)
KRASGTPase KRas. (203 aa)
LOC102385776Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (128 aa)
PRMT8Protein arginine N-methyltransferase 8; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (447 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
PGRProgesterone receptor. (338 aa)
NCOA1Nuclear receptor coactivator. (1488 aa)
POLR2DDNA-directed RNA polymerase II subunit RPB4. (104 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (43 aa)
GNB1Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa)
GATA3Trans-acting T-cell-specific transcription factor GATA-3. (385 aa)
MYBTranscriptional activator Myb isoform X1. (764 aa)
POLR2IDNA-directed RNA polymerase II subunit RPB9 isoform X1. (133 aa)
LOC102374839Serine/threonine-protein phosphatase 5-like. (622 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
STRN4Striatin-4. (690 aa)
USF1Upstream stimulatory factor 1 isoform X1. (361 aa)
LOC102383253Uncharacterized protein LOC102383253. (376 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
XPO1Exportin-1 isoform X1. (1071 aa)
LOC102384725Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
HRASGTPase HRas. (189 aa)
LOC102373634Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (86 aa)
LOC102388444Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
AREGAmphiregulin. (226 aa)
TBPL2TATA box-binding protein-like protein 2 isoform X1. (331 aa)
LOC112547860GTPase HRas-like. (186 aa)
WDR64WD repeat-containing protein 64. (1145 aa)
LOC102383137Histone H2A; Belongs to the histone H2A family. (140 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
CDK9Cyclin-dependent kinase 9. (321 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (566 aa)
POLR2LDNA-directed RNA polymerases I, II, and III subunit RPABC5. (67 aa)
LOC102382262Histone H2B; Belongs to the histone H2B family. (126 aa)
HSP90AB1Heat shock protein HSP 90-beta. (729 aa)
POLR2EDNA-directed RNA polymerases I, II, and III subunit RPABC1. (210 aa)
TBPTATA-box-binding protein. (301 aa)
USF2Upstream stimulatory factor 2 isoform X1. (332 aa)
LOC102379984Histone H2B; Belongs to the histone H2B family. (118 aa)
LOC102383903Histone H2B-like; Belongs to the histone H2B family. (168 aa)
TBPL1TATA box-binding protein-like protein 1. (186 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
POLR2CDNA-directed RNA polymerase II subunit RPB3. (275 aa)
ZC3H12AEndoribonuclease ZC3H12A. (697 aa)
ZDHHC21Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa)
MMP7Matrilysin. (263 aa)
NRASGTPase NRas. (97 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
LOC102384812Integumentary mucin C.1-like. (249 aa)
CREB1Cyclic AMP-responsive element-binding protein 1. (327 aa)
LOC102373170Histone H2B; Belongs to the histone H2B family. (126 aa)
FKBP4Peptidylprolyl isomerase. (453 aa)
POLR2KDNA-directed RNA polymerases I, II, and III subunit RPABC4. (58 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta isoform X1. (727 aa)
EBAG9Receptor-binding cancer antigen expressed on SiSo cells; May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases. (212 aa)
HSPB1Heat shock protein beta-1; Belongs to the small heat shock protein (HSP20) family. (217 aa)
KANK4KN motif and ankyrin repeat domain-containing protein 4 isoform X1. (1043 aa)
LOC102372061Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
MMP9Matrix metalloproteinase-9. (684 aa)
LOC102385431Histone H2B; Belongs to the histone H2B family. (166 aa)
ZC3H12BProbable ribonuclease ZC3H12B. (836 aa)
PPIDPeptidyl-prolyl cis-trans isomerase D isoform X1. (370 aa)
LOC102384519Histone H2B; Belongs to the histone H2B family. (126 aa)
NRIP1Nuclear receptor-interacting protein 1. (1162 aa)
EP300Histone acetyltransferase p300 isoform X1. (2149 aa)
LOC102379915Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (119 aa)
CCNT1cyclin-T1; Belongs to the cyclin family. (731 aa)
LOC102387686Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC102385673Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
POLR2FDNA-directed RNA polymerases I, II, and III subunit RPABC2. (127 aa)
LOC102374986Histone-arginine methyltransferase CARM1-like isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (532 aa)
FKBP5Peptidylprolyl isomerase. (457 aa)
ESR2Estrogen receptor beta isoform X1. (548 aa)
S1PR3Sphingosine 1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (380 aa)
Your Current Organism:
Alligator sinensis
NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494
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