34 items (Alligator sinensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PCSK4	LOW QUALITY PROTEIN: proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (727 aa)
	LOC102371934	Vitellogenin-2-like. (1805 aa)
	LOC102371686	Vitellogenin-2-like. (1753 aa)
	CETP	LOW QUALITY PROTEIN: cholesteryl ester transfer protein. (223 aa)
	FURIN	Furin isoform X1; Belongs to the peptidase S8 family. (804 aa)
	APOA5	Apolipoprotein A-V isoform X1. (365 aa)
	LMF1	Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family. (414 aa)
	LPL	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (520 aa)
	LOC102377482	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (802 aa)
	PCSK6	Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (885 aa)
	LOC102387409	Apolipoprotein A-II-like. (103 aa)
	LOC102382111	Microsomal triglyceride transfer protein-like isoform X1. (888 aa)
	LOC102388283	Prostate stem cell antigen-like. (125 aa)
	LMF2	Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family. (548 aa)
	LOC102383324	Uncharacterized protein LOC102383324. (3867 aa)
	APOA4	Apolipoprotein A-IV isoform X1. (396 aa)
	LIPC	Hepatic triacylglycerol lipase. (498 aa)
	ANGPTL4	Angiopoietin-related protein 4. (284 aa)
	APOE	Apolipoprotein E isoform X1. (252 aa)
	LOC102384651	Apolipoprotein B-100-like. (991 aa)
	P4HB	Protein disulfide-isomerase. (427 aa)
	APOF	Apolipoprotein F. (439 aa)
	PLTP	Phospholipid transfer protein. (489 aa)
	LOC102387462	Lymphocyte antigen 6E-like. (126 aa)
	APOA1	Apolipoprotein A-I. (259 aa)
	LOC102387204	Lymphocyte antigen 6E-like. (128 aa)
	LCAT	Phosphatidylcholine-sterol acyltransferase. (580 aa)
	APOB	Apolipoprotein B-100. (3654 aa)
	LOC102387708	Lymphocyte antigen 6E-like. (127 aa)
	PCSK5	Proprotein convertase subtilisin/kexin type 5; Belongs to the peptidase S8 family. (1896 aa)
	ANGPTL3	Angiopoietin-related protein 3. (462 aa)
	MTTP	Microsomal triglyceride transfer protein large subunit. (893 aa)
	LOC102371294	Vitellogenin-1-like. (1815 aa)
	PDIA2	Protein disulfide-isomerase A2. (533 aa)

Your Current Organism:

Alligator sinensis

NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANGPTL3	APOA5	A0A1U7S1B5	A0A3Q0H6S2	Angiopoietin-related protein 3.	Apolipoprotein A-V isoform X1.	0.605
ANGPTL3	APOB	A0A1U7S1B5	A0A1U7SB35	Angiopoietin-related protein 3.	Apolipoprotein B-100.	0.477
ANGPTL3	LOC102377482	A0A1U7S1B5	A0A3Q0GI02	Angiopoietin-related protein 3.	Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]	0.424
ANGPTL3	LOC102383324	A0A1U7S1B5	A0A1U8DBU7	Angiopoietin-related protein 3.	Uncharacterized protein LOC102383324.	0.423
ANGPTL3	LOC102384651	A0A1U7S1B5	A0A1U7SVD5	Angiopoietin-related protein 3.	Apolipoprotein B-100-like.	0.477
ANGPTL4	LMF1	A0A1U8D515	A0A3Q0GQJ0	Angiopoietin-related protein 4.	Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family.	0.440
APOA1	APOA4	A0A1U7SH51	A0A1U8DBC9	Apolipoprotein A-I.	Apolipoprotein A-IV isoform X1.	0.640
APOA1	APOB	A0A1U7SH51	A0A1U7SB35	Apolipoprotein A-I.	Apolipoprotein B-100.	0.684
APOA1	APOE	A0A1U7SH51	A0A1U7SXQ0	Apolipoprotein A-I.	Apolipoprotein E isoform X1.	0.766
APOA1	CETP	A0A1U7SH51	A0A3Q0HDA9	Apolipoprotein A-I.	LOW QUALITY PROTEIN: cholesteryl ester transfer protein.	0.529
APOA1	LCAT	A0A1U7SH51	A0A1U7SCL8	Apolipoprotein A-I.	Phosphatidylcholine-sterol acyltransferase.	0.634
APOA1	LOC102371294	A0A1U7SH51	A0A1U7RZ93	Apolipoprotein A-I.	Vitellogenin-1-like.	0.585
APOA1	LOC102371686	A0A1U7SH51	A0A3Q0HHV8	Apolipoprotein A-I.	Vitellogenin-2-like.	0.585
APOA1	LOC102371934	A0A1U7SH51	A0A3Q0HIN3	Apolipoprotein A-I.	Vitellogenin-2-like.	0.585
APOA1	LOC102383324	A0A1U7SH51	A0A1U8DBU7	Apolipoprotein A-I.	Uncharacterized protein LOC102383324.	0.684
APOA1	LOC102384651	A0A1U7SH51	A0A1U7SVD5	Apolipoprotein A-I.	Apolipoprotein B-100-like.	0.684
APOA1	LOC102387409	A0A1U7SH51	A0A3Q0FWD5	Apolipoprotein A-I.	Apolipoprotein A-II-like.	0.749
APOA1	PLTP	A0A1U7SH51	A0A1U7SQ12	Apolipoprotein A-I.	Phospholipid transfer protein.	0.688
APOA4	APOA1	A0A1U8DBC9	A0A1U7SH51	Apolipoprotein A-IV isoform X1.	Apolipoprotein A-I.	0.640
APOA4	APOB	A0A1U8DBC9	A0A1U7SB35	Apolipoprotein A-IV isoform X1.	Apolipoprotein B-100.	0.581