28 items (Alligator sinensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PHKG1	Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform; Belongs to the protein kinase superfamily. (388 aa)
	GYG1	Glycogenin-1. (264 aa)
	LOC102372584	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (1316 aa)
	VAX2	Ventral anterior homeobox 2. (263 aa)
	PHKA1	Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Belongs to the phosphorylase b kinase regulatory chain family. (1299 aa)
	EPM2A	Laforin. (192 aa)
	GYS2	Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (725 aa)
	GBE1	1,4-alpha-glucan-branching enzyme. (592 aa)
	UGP2	UTP--glucose-1-phosphate uridylyltransferase. (523 aa)
	LOC106723017	1,4-alpha-glucan-branching enzyme-like. (100 aa)
	PHKG2	Phosphorylase b kinase gamma catalytic chain, liver/testis isoform. (331 aa)
	PHKB	Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. (1090 aa)
	PGM1	Phosphoglucomutase-1 isoform X1; Belongs to the phosphohexose mutase family. (566 aa)
	PPP1R3E	Protein phosphatase 1 regulatory subunit 3E. (305 aa)
	PPP1R3B	Protein phosphatase 1 regulatory subunit 3B isoform X1. (301 aa)
	LOC102385581	SITS-binding protein-like isoform X1; Belongs to the glycosyl hydrolase 31 family. (706 aa)
	AGL	Glycogen debranching enzyme isoform X1. (1531 aa)
	PPP1R3D	Protein phosphatase 1 regulatory subunit 3D. (202 aa)
	PYGB	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (839 aa)
	PYGL	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (864 aa)
	NHLRC1	E3 ubiquitin-protein ligase NHLRC1. (400 aa)
	PGM5	Phosphoglucomutase-like protein 5 isoform X1. (484 aa)
	PHKA2	Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Belongs to the phosphorylase b kinase regulatory chain family. (1244 aa)
	GYS1	Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (617 aa)
	GAA	Lysosomal alpha-glucosidase; Belongs to the glycosyl hydrolase 31 family. (857 aa)
	LOC102374870	Myogenesis-regulating glycosidase isoform X1; Belongs to the glycosyl hydrolase 31 family. (798 aa)
	LOC102380364	Myogenesis-regulating glycosidase-like; Belongs to the glycosyl hydrolase 31 family. (704 aa)
	PPP1R3C	Protein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. (315 aa)

Your Current Organism:

Alligator sinensis

NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGL	EPM2A	A0A1U7RIN6	A0A3Q0GLP3	Glycogen debranching enzyme isoform X1.	Laforin.	0.545
AGL	GBE1	A0A1U7RIN6	A0A1U8DX83	Glycogen debranching enzyme isoform X1.	1,4-alpha-glucan-branching enzyme.	0.976
AGL	GYG1	A0A1U7RIN6	A0A3Q0HFS5	Glycogen debranching enzyme isoform X1.	Glycogenin-1.	0.975
AGL	GYS1	A0A1U7RIN6	A0A3Q0G169	Glycogen debranching enzyme isoform X1.	Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.	0.826
AGL	GYS2	A0A1U7RIN6	A0A1U8DHE6	Glycogen debranching enzyme isoform X1.	Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.	0.826
AGL	LOC102372584	A0A1U7RIN6	A0A3Q0HFG4	Glycogen debranching enzyme isoform X1.	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	0.991
AGL	LOC106723017	A0A1U7RIN6	A0A3Q0FRG5	Glycogen debranching enzyme isoform X1.	1,4-alpha-glucan-branching enzyme-like.	0.772
AGL	NHLRC1	A0A1U7RIN6	A0A1U7S0W5	Glycogen debranching enzyme isoform X1.	E3 ubiquitin-protein ligase NHLRC1.	0.565
AGL	PGM1	A0A1U7RIN6	A0A1U7SCB2	Glycogen debranching enzyme isoform X1.	Phosphoglucomutase-1 isoform X1; Belongs to the phosphohexose mutase family.	0.978
AGL	PGM5	A0A1U7RIN6	A0A3Q0GKB7	Glycogen debranching enzyme isoform X1.	Phosphoglucomutase-like protein 5 isoform X1.	0.718
AGL	PYGB	A0A1U7RIN6	A0A1U7RRK1	Glycogen debranching enzyme isoform X1.	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	0.994
AGL	PYGL	A0A1U7RIN6	A0A1U7RSA6	Glycogen debranching enzyme isoform X1.	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	0.994
AGL	UGP2	A0A1U7RIN6	A0A3Q0FPN6	Glycogen debranching enzyme isoform X1.	UTP--glucose-1-phosphate uridylyltransferase.	0.957
EPM2A	AGL	A0A3Q0GLP3	A0A1U7RIN6	Laforin.	Glycogen debranching enzyme isoform X1.	0.545
EPM2A	GYS1	A0A3Q0GLP3	A0A3Q0G169	Laforin.	Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.	0.450
EPM2A	GYS2	A0A3Q0GLP3	A0A1U8DHE6	Laforin.	Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.	0.450
EPM2A	NHLRC1	A0A3Q0GLP3	A0A1U7S0W5	Laforin.	E3 ubiquitin-protein ligase NHLRC1.	0.910
GAA	GYG1	A0A3Q0FTC9	A0A3Q0HFS5	Lysosomal alpha-glucosidase; Belongs to the glycosyl hydrolase 31 family.	Glycogenin-1.	0.498
GBE1	AGL	A0A1U8DX83	A0A1U7RIN6	1,4-alpha-glucan-branching enzyme.	Glycogen debranching enzyme isoform X1.	0.976
GBE1	GYG1	A0A1U8DX83	A0A3Q0HFS5	1,4-alpha-glucan-branching enzyme.	Glycogenin-1.	0.988