STRINGSTRING
ZDHHC7 ZDHHC7 CAV3 CAV3 PIK3R1 PIK3R1 XPO1 XPO1 HRAS HRAS AREG AREG LOC112547860 LOC112547860 PIK3R2 PIK3R2 CREB1 CREB1 MMP7 MMP7 PRMT1 PRMT1 UHMK1 UHMK1 PDPK1 PDPK1 ELK1 ELK1 CSDE1 CSDE1 MMP9 MMP9 GNG13 GNG13 AKT2 AKT2 NRAS NRAS ESR2 ESR2 S1PR3 S1PR3 AKT1 AKT1 ZDHHC21 ZDHHC21 KRAS KRAS LOC102380057 LOC102380057 HBEGF HBEGF LOC112550695 LOC112550695 EGF EGF CAV2 CAV2 ESR1 ESR1 GNG2 GNG2 CAV1 CAV1 AKT3 AKT3 STRN3 STRN3 EPGN EPGN EREG EREG STRN STRN BTC BTC GNB4 GNB4 PIK3CA PIK3CA WDR64 WDR64 LOC102385776 LOC102385776 PRMT8 PRMT8 GNG5 GNG5 GNB1 GNB1 GNG4 GNG4 STRN4 STRN4 TGFA TGFA LOC102372061 LOC102372061 HSPB1 HSPB1 GNGT2 GNGT2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ZDHHC7Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (305 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (724 aa)
XPO1Exportin-1 isoform X1. (1071 aa)
HRASGTPase HRas. (189 aa)
AREGAmphiregulin. (226 aa)
LOC112547860GTPase HRas-like. (186 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta isoform X1. (727 aa)
CREB1Cyclic AMP-responsive element-binding protein 1. (327 aa)
MMP7Matrilysin. (263 aa)
PRMT1Protein arginine N-methyltransferase 1 isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (365 aa)
UHMK1Serine/threonine-protein kinase Kist isoform X1. (366 aa)
PDPK13-phosphoinositide-dependent protein kinase 1 isoform X2. (701 aa)
ELK1ETS domain-containing protein Elk-1 isoform X1. (396 aa)
CSDE1Cold shock domain-containing protein E1 isoform X1. (843 aa)
MMP9Matrix metalloproteinase-9. (684 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
NRASGTPase NRas. (97 aa)
ESR2Estrogen receptor beta isoform X1. (548 aa)
S1PR3Sphingosine 1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (380 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
ZDHHC21Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa)
KRASGTPase KRas. (203 aa)
LOC102380057Phosphatidylinositol 3-kinase regulatory subunit gamma. (419 aa)
HBEGFProheparin-binding EGF-like growth factor. (200 aa)
LOC112550695Phosphatidylinositol 3-kinase regulatory subunit alpha-like. (322 aa)
EGFPro-epidermal growth factor. (1257 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (153 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (627 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (93 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (128 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa)
STRN3Striatin-3. (712 aa)
EPGNEpigen isoform X1. (171 aa)
EREGProepiregulin. (173 aa)
STRNStriatin isoform X1. (706 aa)
BTCProbetacellulin. (175 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4. (340 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
WDR64WD repeat-containing protein 64. (1145 aa)
LOC102385776Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (128 aa)
PRMT8Protein arginine N-methyltransferase 8; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (447 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (43 aa)
GNB1Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. (340 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
STRN4Striatin-4. (690 aa)
TGFAProtransforming growth factor alpha isoform X1. (190 aa)
LOC102372061Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
HSPB1Heat shock protein beta-1; Belongs to the small heat shock protein (HSP20) family. (217 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
Your Current Organism:
Alligator sinensis
NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494
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