35 items (Alligator sinensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

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co-expression

protein homology

Your Input:
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
	MTR	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1264 aa)
	RAB7A	Ras-related protein Rab-7a. (207 aa)
	NIPSNAP2	Protein NipSnap homolog 2. (313 aa)
	UACA	Uveal autoantigen with coiled-coil domains and ankyrin repeats. (1442 aa)
	NSFL1C	NSFL1 cofactor p47. (396 aa)
	VAMP3	Vesicle-associated membrane protein 3. (104 aa)
	FAM91A1	Protein FAM91A1 isoform X1. (849 aa)
	TMEM59	Transmembrane protein 59 isoform X1. (189 aa)
	VCP	Transitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family. (761 aa)
	LDLRAD1	Low-density lipoprotein receptor class A domain-containing protein 1. (209 aa)
	SPATA5	Spermatogenesis-associated protein 5 isoform X1. (831 aa)
	CAV1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (128 aa)
	SLC4A7	Anion exchange protein. (1246 aa)
	ROCK2	Rho-associated protein kinase 2 isoform X1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1455 aa)
	RALGAPA2	Ral GTPase-activating protein subunit alpha-2 isoform X1. (1920 aa)
	RALGAPA1	Ral GTPase-activating protein subunit alpha-1 isoform X1. (1867 aa)
	DBT	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (480 aa)
	PAK5	Non-specific serine/threonine protein kinase. (691 aa)
	PAK4	Non-specific serine/threonine protein kinase. (428 aa)
	DBN1	LOW QUALITY PROTEIN: drebrin. (691 aa)
	LOC102379235	Tyrosine-protein kinase. (612 aa)
	NIPSNAP1	Protein NipSnap homolog 1. (304 aa)
	RHOH	Rho-related GTP-binding protein RhoH. (191 aa)
	JUP	Junction plakoglobin. (743 aa)
	ARHGDIG	Rho GDP-dissociation inhibitor 3. (205 aa)
	ARHGDIA	Rho GDP-dissociation inhibitor 1. (205 aa)
	PAK2	Non-specific serine/threonine protein kinase. (525 aa)
	SPATA5L1	Spermatogenesis-associated protein 5-like protein 1; Belongs to the AAA ATPase family. (628 aa)
	LAMTOR1	Ragulator complex protein LAMTOR1. (161 aa)
	ROCK1	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1377 aa)
	UBXN2B	UBX domain-containing protein 2B. (410 aa)
	WDR11	WD repeat-containing protein 11. (1192 aa)
	ARHGDIB	Rho GDP-dissociation inhibitor 2. (200 aa)
	PAK6	Non-specific serine/threonine protein kinase. (675 aa)

Your Current Organism:

Alligator sinensis

NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGDIA	RHOH	A0A1U7SXY4	A0A1U8DJV9	Rho GDP-dissociation inhibitor 1.	Rho-related GTP-binding protein RhoH.	0.761
ARHGDIB	RHOH	A0A1U7RQQ3	A0A1U8DJV9	Rho GDP-dissociation inhibitor 2.	Rho-related GTP-binding protein RhoH.	0.761
ARHGDIG	RHOH	A0A1U8D1C8	A0A1U8DJV9	Rho GDP-dissociation inhibitor 3.	Rho-related GTP-binding protein RhoH.	0.761
CAV1	CAV3	A0A3Q0GJR4	A0A1U7RQL9	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.961
CAV1	JUP	A0A3Q0GJR4	A0A1U8DEU3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Junction plakoglobin.	0.558
CAV1	RHOH	A0A3Q0GJR4	A0A1U8DJV9	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Rho-related GTP-binding protein RhoH.	0.413
CAV1	VAMP3	A0A3Q0GJR4	A0A3Q0H9R6	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Vesicle-associated membrane protein 3.	0.400
CAV3	CAV1	A0A1U7RQL9	A0A3Q0GJR4	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.961
CAV3	JUP	A0A1U7RQL9	A0A1U8DEU3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Junction plakoglobin.	0.522
CAV3	RHOH	A0A1U7RQL9	A0A1U8DJV9	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Rho-related GTP-binding protein RhoH.	0.445
CAV3	SPATA5	A0A1U7RQL9	A0A3Q0GQU0	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Spermatogenesis-associated protein 5 isoform X1.	0.409
CAV3	SPATA5L1	A0A1U7RQL9	A0A1U7SHA8	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Spermatogenesis-associated protein 5-like protein 1; Belongs to the AAA ATPase family.	0.409
CAV3	VAMP3	A0A1U7RQL9	A0A3Q0H9R6	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Vesicle-associated membrane protein 3.	0.491
CAV3	VCP	A0A1U7RQL9	A0A3Q0GU32	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Transitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family.	0.624
DBT	JUP	A0A3Q0FZU5	A0A1U8DEU3	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Junction plakoglobin.	0.456
DBT	LDLRAD1	A0A3Q0FZU5	A0A3Q0GRN7	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Low-density lipoprotein receptor class A domain-containing protein 1.	0.403
DBT	LOC102379235	A0A3Q0FZU5	A0A3Q0FMM4	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Tyrosine-protein kinase.	0.401
DBT	MTR	A0A3Q0FZU5	A0A1U7RE83	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.609
DBT	NIPSNAP1	A0A3Q0FZU5	A0A1U8DKQ2	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Protein NipSnap homolog 1.	0.522
DBT	NIPSNAP2	A0A3Q0FZU5	A0A3Q0HGM7	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	Protein NipSnap homolog 2.	0.522