80 items (Alligator sinensis) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

Your Input:
	PRMT8	Protein arginine N-methyltransferase 8; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (447 aa)
	CITED1	Cbp/p300-interacting transactivator 1. (220 aa)
	KANK3	LOW QUALITY PROTEIN: KN motif and ankyrin repeat domain-containing protein 3. (1039 aa)
	LOC102387438	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (442 aa)
	CXXC5	CXXC-type zinc finger protein 5 isoform X1. (303 aa)
	ESR1	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (627 aa)
	FKBP4	Peptidylprolyl isomerase. (453 aa)
	POLR2K	DNA-directed RNA polymerases I, II, and III subunit RPABC4. (58 aa)
	EBAG9	Receptor-binding cancer antigen expressed on SiSo cells; May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases. (212 aa)
	KANK4	KN motif and ankyrin repeat domain-containing protein 4 isoform X1. (1043 aa)
	LOC102385431	Histone H2B; Belongs to the histone H2B family. (166 aa)
	ZC3H12B	Probable ribonuclease ZC3H12B. (836 aa)
	LOC102384519	Histone H2B; Belongs to the histone H2B family. (126 aa)
	NRIP1	Nuclear receptor-interacting protein 1. (1162 aa)
	LOC102379915	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (119 aa)
	CCNT1	cyclin-T1; Belongs to the cyclin family. (731 aa)
	LOC102387686	Histone H2B; Belongs to the histone H2B family. (126 aa)
	LOC102385673	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
	POLR2F	DNA-directed RNA polymerases I, II, and III subunit RPABC2. (127 aa)
	LOC102374986	Histone-arginine methyltransferase CARM1-like isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (532 aa)
	ZNF217	Zinc finger protein 217. (1073 aa)
	TRPS1	Zinc finger transcription factor Trps1 isoform X1. (1294 aa)
	HSP90AA1	Heat shock protein HSP 90-alpha. (728 aa)
	GREB1L	LOW QUALITY PROTEIN: GREB1-like protein. (1966 aa)
	LOC102384030	Histone H2B; Belongs to the histone H2B family. (126 aa)
	POLR2H	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
	LOC102384725	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
	LOC102373634	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (86 aa)
	LOC102388444	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
	TBPL2	TATA box-binding protein-like protein 2 isoform X1. (331 aa)
	POLR2J	DNA-directed RNA polymerase II subunit RPB11-a. (114 aa)
	ZC3H12C	Probable ribonuclease ZC3H12C isoform X1. (920 aa)
	LOC102382262	Histone H2B; Belongs to the histone H2B family. (126 aa)
	HSP90AB1	Heat shock protein HSP 90-beta. (729 aa)
	POLR2E	DNA-directed RNA polymerases I, II, and III subunit RPABC1. (210 aa)
	TBP	TATA-box-binding protein. (301 aa)
	KANK2	KN motif and ankyrin repeat domain-containing protein 2 isoform X1. (844 aa)
	KANK1	KN motif and ankyrin repeat domain-containing protein 1 isoform X1. (1366 aa)
	CARM1	Histone-arginine methyltransferase CARM1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (548 aa)
	GTF2A1L	TFIIA-alpha and beta-like factor. (441 aa)
	GREB1	Protein GREB1. (1951 aa)
	FOXA1	Hepatocyte nuclear factor 3-alpha. (190 aa)
	FOXA2	LOW QUALITY PROTEIN: hepatocyte nuclear factor 3-beta. (321 aa)
	GTF2A2	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa)
	NCOA2	Nuclear receptor coactivator. (1462 aa)
	CBFB	Core-binding factor subunit beta isoform X1. (211 aa)
	DDX5	Probable ATP-dependent RNA helicase DDX5; Belongs to the DEAD box helicase family. (611 aa)
	GTF2A1	Transcription initiation factor IIA subunit 1 isoform X1. (401 aa)
	PRMT1	Protein arginine N-methyltransferase 1 isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (365 aa)
	POLR2A	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1960 aa)
	NCOA3	Nuclear receptor coactivator. (1438 aa)
	PTGES3	Prostaglandin E synthase 3. (179 aa)
	GTF2F2	General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (268 aa)
	LOC102380682	Vegetative cell wall protein gp1-like. (393 aa)
	KDM1A	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (751 aa)
	POLR2G	DNA-directed RNA polymerase II subunit RPB7. (170 aa)
	LOC102387236	Endoribonuclease ZC3H12A. (523 aa)
	YY1	Transcriptional repressor protein YY1. (212 aa)
	CREBBP	CREB-binding protein. (2468 aa)
	LOC102383137	Histone H2A; Belongs to the histone H2A family. (140 aa)
	CDK9	Cyclin-dependent kinase 9. (321 aa)
	GTF2F1	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (566 aa)
	POLR2L	DNA-directed RNA polymerases I, II, and III subunit RPABC5. (67 aa)
	EP300	Histone acetyltransferase p300 isoform X1. (2149 aa)
	USF2	Upstream stimulatory factor 2 isoform X1. (332 aa)
	LOC102379984	Histone H2B; Belongs to the histone H2B family. (118 aa)
	LOC102383903	Histone H2B-like; Belongs to the histone H2B family. (168 aa)
	TBPL1	TATA box-binding protein-like protein 1. (186 aa)
	POLR2C	DNA-directed RNA polymerase II subunit RPB3. (275 aa)
	ZC3H12A	Endoribonuclease ZC3H12A. (697 aa)
	LOC102384812	Integumentary mucin C.1-like. (249 aa)
	LOC102373170	Histone H2B; Belongs to the histone H2B family. (126 aa)
	USF1	Upstream stimulatory factor 1 isoform X1. (361 aa)
	POLR2I	DNA-directed RNA polymerase II subunit RPB9 isoform X1. (133 aa)
	MYB	Transcriptional activator Myb isoform X1. (764 aa)
	GATA3	Trans-acting T-cell-specific transcription factor GATA-3. (385 aa)
	POLR2D	DNA-directed RNA polymerase II subunit RPB4. (104 aa)
	NCOA1	Nuclear receptor coactivator. (1488 aa)
	PGR	Progesterone receptor. (338 aa)
	POLR2B	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)

Your Current Organism:

Alligator sinensis

NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CARM1	CREBBP	A0A3Q0GJS6	A0A1U8DJG6	Histone-arginine methyltransferase CARM1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	CREB-binding protein.	0.799
CARM1	DDX5	A0A3Q0GJS6	A0A3Q0G0U6	Histone-arginine methyltransferase CARM1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Probable ATP-dependent RNA helicase DDX5; Belongs to the DEAD box helicase family.	0.428
CARM1	EP300	A0A3Q0GJS6	A0A1U8D7N2	Histone-arginine methyltransferase CARM1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Histone acetyltransferase p300 isoform X1.	0.871
CARM1	ESR1	A0A3Q0GJS6	A0A3Q0GNM7	Histone-arginine methyltransferase CARM1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.505
CARM1	FOXA1	A0A3Q0GJS6	A0A3Q0GGN2	Histone-arginine methyltransferase CARM1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Hepatocyte nuclear factor 3-alpha.	0.459
CARM1	FOXA2	A0A3Q0GJS6	A0A3Q0GER6	Histone-arginine methyltransferase CARM1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	LOW QUALITY PROTEIN: hepatocyte nuclear factor 3-beta.	0.459
CARM1	GATA3	A0A3Q0GJS6	A0A3Q0HAJ7	Histone-arginine methyltransferase CARM1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Trans-acting T-cell-specific transcription factor GATA-3.	0.444
CARM1	NCOA1	A0A3Q0GJS6	A0A3Q0H477	Histone-arginine methyltransferase CARM1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Nuclear receptor coactivator.	0.627
CARM1	NCOA2	A0A3Q0GJS6	A0A3Q0G977	Histone-arginine methyltransferase CARM1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Nuclear receptor coactivator.	0.627
CARM1	NCOA3	A0A3Q0GJS6	A0A3Q0FJH7	Histone-arginine methyltransferase CARM1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Nuclear receptor coactivator.	0.627
CARM1	PRMT1	A0A3Q0GJS6	A0A3Q0FXE4	Histone-arginine methyltransferase CARM1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Protein arginine N-methyltransferase 1 isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.719
CARM1	PRMT8	A0A3Q0GJS6	A0A3Q0GZI7	Histone-arginine methyltransferase CARM1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	Protein arginine N-methyltransferase 8; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.588
CARM1	TBP	A0A3Q0GJS6	A0A1U7R4B2	Histone-arginine methyltransferase CARM1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	TATA-box-binding protein.	0.424
CARM1	TBPL2	A0A3Q0GJS6	A0A1U7RIK6	Histone-arginine methyltransferase CARM1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	TATA box-binding protein-like protein 2 isoform X1.	0.424
CBFB	CREBBP	A0A3Q0G438	A0A1U8DJG6	Core-binding factor subunit beta isoform X1.	CREB-binding protein.	0.626
CBFB	EP300	A0A3Q0G438	A0A1U8D7N2	Core-binding factor subunit beta isoform X1.	Histone acetyltransferase p300 isoform X1.	0.668
CBFB	GATA3	A0A3Q0G438	A0A3Q0HAJ7	Core-binding factor subunit beta isoform X1.	Trans-acting T-cell-specific transcription factor GATA-3.	0.686
CBFB	PRMT1	A0A3Q0G438	A0A3Q0FXE4	Core-binding factor subunit beta isoform X1.	Protein arginine N-methyltransferase 1 isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.669
CBFB	PRMT8	A0A3Q0G438	A0A3Q0GZI7	Core-binding factor subunit beta isoform X1.	Protein arginine N-methyltransferase 8; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.607
CBFB	TRPS1	A0A3Q0G438	A0A1U7RSD9	Core-binding factor subunit beta isoform X1.	Zinc finger transcription factor Trps1 isoform X1.	0.419