31 items (Alligator sinensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SFN	14-3-3 protein sigma; Belongs to the 14-3-3 family. (246 aa)
	BTG1	Protein BTG1. (157 aa)
	NFYB	Nuclear transcription factor Y subunit beta isoform X1. (221 aa)
	SIRT3	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (390 aa)
	YWHAZ	14-3-3 protein zeta/delta; Belongs to the 14-3-3 family. (245 aa)
	SMAD3	Mothers against decapentaplegic homolog. (321 aa)
	FOXG1	Forkhead box protein G1. (345 aa)
	MSTN	LOW QUALITY PROTEIN: growth/differentiation factor 8. (375 aa)
	AKT2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
	YWHAQ	14-3-3 protein theta; Belongs to the 14-3-3 family. (245 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	DDIT3	DNA damage-inducible transcript 3 protein. (184 aa)
	FOXO4	Forkhead box protein O4 isoform X1. (427 aa)
	FOXO1	Forkhead box protein O1. (473 aa)
	EP300	Histone acetyltransferase p300 isoform X1. (2149 aa)
	GDF11	Growth/differentiation factor 11. (342 aa)
	CREBBP	CREB-binding protein. (2468 aa)
	SMAD2	Mothers against decapentaplegic homolog. (467 aa)
	BCL6B	B-cell CLL/lymphoma 6 member B protein isoform X1. (503 aa)
	AKT3	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa)
	NFYA	Nuclear transcription factor Y subunit alpha isoform X1. (401 aa)
	PPARGC1A	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X1. (810 aa)
	CCNG2	cyclin-G2 isoform X1; Belongs to the cyclin family. (362 aa)
	FOXO3	Forkhead box protein O3. (488 aa)
	LOC102373921	Mothers against decapentaplegic homolog. (405 aa)
	NFYC	Nuclear transcription factor Y subunit gamma isoform X1. (343 aa)
	FOXO6	Forkhead box protein O6. (491 aa)
	SMAD4	Mothers against decapentaplegic homolog. (554 aa)
	YWHAB	14-3-3 protein beta/alpha; Belongs to the 14-3-3 family. (279 aa)
	BCL6	B-cell lymphoma 6 protein isoform X1. (708 aa)
	SIRT1	NAD-dependent protein deacetylase sirtuin-1 isoform X1. (557 aa)

Your Current Organism:

Alligator sinensis

NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	AKT2	A0A1U7SR37	A0A1U7SGJ4	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.900
AKT1	AKT3	A0A1U7SR37	A0A3Q0GH87	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.901
AKT1	EP300	A0A1U7SR37	A0A1U8D7N2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Histone acetyltransferase p300 isoform X1.	0.406
AKT1	FOXG1	A0A1U7SR37	A0A1U7SFU8	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Forkhead box protein G1.	0.432
AKT1	FOXO1	A0A1U7SR37	A0A1U8D525	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Forkhead box protein O1.	0.971
AKT1	FOXO3	A0A1U7SR37	A0A3Q0H544	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Forkhead box protein O3.	0.971
AKT1	FOXO4	A0A1U7SR37	A0A1U8D385	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Forkhead box protein O4 isoform X1.	0.971
AKT1	FOXO6	A0A1U7SR37	A0A3Q0HEV4	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Forkhead box protein O6.	0.971
AKT1	LOC102373921	A0A1U7SR37	A0A3Q0H8N6	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Mothers against decapentaplegic homolog.	0.409
AKT1	SIRT1	A0A1U7SR37	A0A1U7RVX8	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	NAD-dependent protein deacetylase sirtuin-1 isoform X1.	0.410
AKT1	SMAD4	A0A1U7SR37	A0A3Q0HG95	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Mothers against decapentaplegic homolog.	0.409
AKT2	AKT1	A0A1U7SGJ4	A0A1U7SR37	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.900
AKT2	AKT3	A0A1U7SGJ4	A0A3Q0GH87	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.901
AKT2	EP300	A0A1U7SGJ4	A0A1U8D7N2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Histone acetyltransferase p300 isoform X1.	0.406
AKT2	FOXG1	A0A1U7SGJ4	A0A1U7SFU8	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Forkhead box protein G1.	0.432
AKT2	FOXO1	A0A1U7SGJ4	A0A1U8D525	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Forkhead box protein O1.	0.971
AKT2	FOXO3	A0A1U7SGJ4	A0A3Q0H544	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Forkhead box protein O3.	0.971
AKT2	FOXO4	A0A1U7SGJ4	A0A1U8D385	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Forkhead box protein O4 isoform X1.	0.971
AKT2	FOXO6	A0A1U7SGJ4	A0A3Q0HEV4	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Forkhead box protein O6.	0.971
AKT2	LOC102373921	A0A1U7SGJ4	A0A3Q0H8N6	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Mothers against decapentaplegic homolog.	0.409