STRINGSTRING
FOXO3 FOXO3 SIRT3 SIRT3 SIRT1 SIRT1 CREBBP CREBBP EP300 EP300 FOXO1 FOXO1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FOXO3Forkhead box protein O3. (488 aa)
SIRT3NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (390 aa)
SIRT1NAD-dependent protein deacetylase sirtuin-1 isoform X1. (557 aa)
CREBBPCREB-binding protein. (2468 aa)
EP300Histone acetyltransferase p300 isoform X1. (2149 aa)
FOXO1Forkhead box protein O1. (473 aa)
Your Current Organism:
Alligator sinensis
NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494
Server load: low (14%) [HD]