STRINGSTRING
LOC102371499 LOC102371499 NME8 NME8 LOC102381244 LOC102381244 AKT2 AKT2 MUL1 MUL1 SPATA5L1 SPATA5L1 SOD1 SOD1 LOC102371582 LOC102371582 SKP2 SKP2 P4HB P4HB LOC102374004 LOC102374004 LOC102373449 LOC102373449 GSK3A GSK3A PSMC4 PSMC4 LOC102384426 LOC102384426 SESN2 SESN2 LOC102381382 LOC102381382 NFE2L1 NFE2L1 MED1 MED1 TXN2 TXN2 PSMA3 PSMA3 EP300 EP300 LOC102379122 LOC102379122 UFD1 UFD1 DESI2 DESI2 UBA52 UBA52 LOC102378383 LOC102378383 LOC102379965 LOC102379965 NFE2L3 NFE2L3 DESI1 DESI1 GSTP1 GSTP1 CREBBP CREBBP LOC102373191 LOC102373191 LOC102372246 LOC102372246 PSMC2 PSMC2 PSMD4 PSMD4 LOC102370280 LOC102370280 LOC102375588 LOC102375588 GPX4 GPX4 LOC106722823 LOC106722823 BLVRA BLVRA PSMB7 PSMB7 AKT1 AKT1 GPX2 GPX2 NOX5 NOX5 GPX7 GPX7 LOC102376346 LOC102376346 LOC102372439 LOC102372439 PPARA PPARA LOC102378748 LOC102378748 PSMD13 PSMD13 PSMB5 PSMB5 GSK3B GSK3B PSMD5 PSMD5 PSMB4 PSMB4 MTFP1 MTFP1 LOC102381867 LOC102381867 PSMD2 PSMD2 PSMD12 PSMD12 PSMA1 PSMA1 NCOR2 NCOR2 KIAA2012 KIAA2012 LOC102381120 LOC102381120 LOC102388588 LOC102388588 SPPL3 SPPL3 NOX4 NOX4 PSME3 PSME3 TXNRD2 TXNRD2 PSME4 PSME4 HELZ2 HELZ2 LOC102382623 LOC102382623 PSMD1 PSMD1 AKT3 AKT3 CARM1 CARM1 PSMD3 PSMD3 LOC102386834 LOC102386834 TXNRD1 TXNRD1 LOC102377416 LOC102377416 LOC102373396 LOC102373396 SPATA5 SPATA5 NCF4 NCF4 ERO1A ERO1A VCP VCP PSMB2 PSMB2 PSMD11 PSMD11 LOC102385608 LOC102385608 SQSTM1 SQSTM1 PSMC1 PSMC1 CUL1 CUL1 SIN3B SIN3B LOC102379126 LOC102379126 MAFK MAFK HM13 HM13 TBL1XR1 TBL1XR1 TGS1 TGS1 PRDX6 PRDX6 LOC112551887 LOC112551887 UBB UBB CCS CCS NCOR1 NCOR1 PSMD10 PSMD10 NME9 NME9 NUDT2 NUDT2 PSMA5 PSMA5 UBXN7 UBXN7 COX3 COX3 COX2 COX2 SOD2 SOD2 NPVF NPVF PSMA4 PSMA4 COIL COIL KLHL17 KLHL17 TXNRD3 TXNRD3 PSMD6 PSMD6 LOC102374986 LOC102374986 BACH2 BACH2 PSMA7 PSMA7 PSMD14 PSMD14 PRDX3 PRDX3 LOC102384186 LOC102384186 BACH1 BACH1 LOC102383053 LOC102383053 HMOX1 HMOX1 LOC102374307 LOC102374307 PRDX2 PRDX2 LOC102380429 LOC102380429 TXN TXN COX1 COX1 PSMD7 PSMD7 NCOA6 NCOA6 SRXN1 SRXN1 PSMF1 PSMF1 HMOX2 HMOX2 LOC102387300 LOC102387300 SIN3A SIN3A LOC102380167 LOC102380167 GPX3 GPX3 SKP1 SKP1 LRPPRC LRPPRC LOC102378286 LOC102378286 CUL3 CUL3 PSMA6 PSMA6 LOC102387169 LOC102387169 UBC UBC PSMD9 PSMD9 FAM45A FAM45A PSMA2 PSMA2 CAT CAT KEAP1 KEAP1 FBXL17 FBXL17 PSMB3 PSMB3 RPS27A RPS27A PDIA2 PDIA2 PSMB1 PSMB1 CUNH1orf198 CUNH1orf198 LOC102383279 LOC102383279 GPX8 GPX8 PSMA8 PSMA8 PRDX1 PRDX1 PSMC5 PSMC5 BLVRB BLVRB SOD3 SOD3 PSMC6 PSMC6 ATF4 ATF4 KLHL18 KLHL18 LOC102367872 LOC102367872 NFE2L2 NFE2L2 NCF1 NCF1 PRDX5 PRDX5 TBL1X TBL1X LOC102381860 LOC102381860 LOC102372937 LOC102372937 LOC102379476 LOC102379476 KXD1 KXD1 PSMC3 PSMC3 RBX1 RBX1 PSMB6 PSMB6 GPX1 GPX1 FABP1 FABP1 GSR GSR PSME2 PSME2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102371499Cytochrome c oxidase assembly protein COX14. (51 aa)
NME8Thioredoxin domain-containing protein 3 isoform X1. (583 aa)
LOC102381244SURF1-like protein; Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 family. (308 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
MUL1Mitochondrial ubiquitin ligase activator of NFKB 1. (355 aa)
SPATA5L1Spermatogenesis-associated protein 5-like protein 1; Belongs to the AAA ATPase family. (628 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
LOC102371582Cytochrome c oxidase subunit 4 isoform 1, mitochondrial isoform X1. (289 aa)
SKP2S-phase kinase-associated protein 2. (418 aa)
P4HBProtein disulfide-isomerase. (427 aa)
LOC102374004Cytochrome c oxidase subunit 5B, mitochondrial. (130 aa)
LOC102373449Hemoglobin subunit beta; Belongs to the globin family. (147 aa)
GSK3AGlycogen synthase kinase-3 alpha. (298 aa)
PSMC426S proteasome regulatory subunit 6B; Belongs to the AAA ATPase family. (402 aa)
LOC102384426Hemoglobin subunit pi; Belongs to the globin family. (142 aa)
SESN2Sestrin-2 isoform X1. (559 aa)
LOC102381382Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (652 aa)
NFE2L1Endoplasmic reticulum membrane sensor NFE2L1. (764 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1565 aa)
TXN2Thioredoxin, mitochondrial. (235 aa)
PSMA3Proteasome subunit alpha type. (260 aa)
EP300Histone acetyltransferase p300 isoform X1. (2149 aa)
LOC102379122Translational activator of cytochrome c oxidase 1 isoform X1. (292 aa)
UFD1Ubiquitin recognition factor in ER-associated degradation protein 1. (302 aa)
DESI2Deubiquitinase DESI2 isoform X1. (183 aa)
UBA52ubiquitin-60S ribosomal protein L40. (104 aa)
LOC102378383Cytochrome c oxidase subunit 6C-2. (78 aa)
LOC102379965Cytochrome c, somatic-like; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
NFE2L3Nuclear factor erythroid 2-related factor 3. (538 aa)
DESI1Desumoylating isopeptidase 1. (144 aa)
GSTP1Glutathione S-transferase P isoform X1; Belongs to the GST superfamily. (211 aa)
CREBBPCREB-binding protein. (2468 aa)
LOC102373191LOW QUALITY PROTEIN: hemoglobin subunit beta-like; Belongs to the globin family. (150 aa)
LOC102372246LOW QUALITY PROTEIN: F-box/LRR-repeat protein 17-like. (135 aa)
PSMC226S proteasome regulatory subunit 7; Belongs to the AAA ATPase family. (428 aa)
PSMD426S proteasome non-ATPase regulatory subunit 4 isoform X1. (408 aa)
LOC102370280Mitochondrial ubiquitin ligase activator of nfkb 1-A-like. (156 aa)
LOC102375588Hemoglobin subunit rho-like; Belongs to the globin family. (106 aa)
GPX4Glutathione peroxidase; Belongs to the glutathione peroxidase family. (112 aa)
LOC106722823Proteasome subunit beta type-8-like isoform X1. (160 aa)
BLVRABiliverdin reductase A; Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor; Belongs to the Gfo/Idh/MocA family. Biliverdin reductase subfamily. (296 aa)
PSMB7Proteasome subunit beta type-7. (211 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
GPX2Glutathione peroxidase; Belongs to the glutathione peroxidase family. (190 aa)
NOX5NADPH oxidase 5. (772 aa)
GPX7Glutathione peroxidase; Belongs to the glutathione peroxidase family. (210 aa)
LOC102376346Cytochrome c oxidase subunit 6A2, mitochondrial; Belongs to the cytochrome c oxidase subunit 6A family. (107 aa)
LOC102372439Hemoglobin subunit epsilon; Belongs to the globin family. (147 aa)
PPARAPeroxisome proliferator-activated receptor alpha isoform X1. (468 aa)
LOC102378748Protein SCO1 homolog, mitochondrial. (270 aa)
PSMD1326S proteasome non-ATPase regulatory subunit 13. (376 aa)
PSMB5Proteasome subunit beta. (249 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X1; Belongs to the protein kinase superfamily. (409 aa)
PSMD526S proteasome non-ATPase regulatory subunit 5. (481 aa)
PSMB4LOW QUALITY PROTEIN: proteasome subunit beta type-4. (305 aa)
MTFP1Mitochondrial fission process protein 1. (109 aa)
LOC102381867F-box/WD repeat-containing protein 1A. (517 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (873 aa)
PSMD1226S proteasome non-ATPase regulatory subunit 12 isoform X2. (404 aa)
PSMA1Proteasome endopeptidase complex. (265 aa)
NCOR2Nuclear receptor corepressor 2 isoform X1. (2608 aa)
KIAA2012LOW QUALITY PROTEIN: uncharacterized protein KIAA2012 homolog. (1359 aa)
LOC102381120Cytochrome c oxidase assembly protein COX18, mitochondrial. (232 aa)
LOC102388588Cytochrome c oxidase subunit 6A, mitochondrial. (132 aa)
SPPL3Signal peptide peptidase-like 3. (462 aa)
NOX4NADPH oxidase 4 isoform X1. (614 aa)
PSME3Proteasome activator complex subunit 3. (193 aa)
TXNRD2Thioredoxin reductase 2, mitochondrial isoform X2. (427 aa)
PSME4Proteasome activator complex subunit 4 isoform X1. (1848 aa)
HELZ2Helicase with zinc finger domain 2. (2821 aa)
LOC102382623Uncharacterized protein LOC102382623 isoform X1. (195 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (491 aa)
CARM1Histone-arginine methyltransferase CARM1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (548 aa)
PSMD326S proteasome non-ATPase regulatory subunit 3. (485 aa)
LOC102386834LOW QUALITY PROTEIN: cytochrome c oxidase assembly protein COX20, mitochondrial. (136 aa)
TXNRD1LOW QUALITY PROTEIN: thioredoxin reductase 1, cytoplasmic. (554 aa)
LOC102377416Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial isoform X1. (133 aa)
LOC102373396Uncharacterized protein LOC102373396. (98 aa)
SPATA5Spermatogenesis-associated protein 5 isoform X1. (831 aa)
NCF4Neutrophil cytosol factor 4 isoform X1. (355 aa)
ERO1AERO1-like protein alpha. (459 aa)
VCPTransitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family. (761 aa)
PSMB2Proteasome subunit beta. (167 aa)
PSMD1126S proteasome non-ATPase regulatory subunit 11. (408 aa)
LOC102385608LOW QUALITY PROTEIN: cytochrome b-245 light chain. (256 aa)
SQSTM1Sequestosome-1 isoform X1. (357 aa)
PSMC126S proteasome regulatory subunit 4; Belongs to the AAA ATPase family. (367 aa)
CUL1Cullin-1 isoform X1; Belongs to the cullin family. (778 aa)
SIN3BPaired amphipathic helix protein Sin3b isoform X1. (1082 aa)
LOC102379126LOW QUALITY PROTEIN: uncharacterized protein LOC102379126. (274 aa)
MAFKTranscription factor MafK isoform X1. (247 aa)
HM13Minor histocompatibility antigen H13 isoform X1. (392 aa)
TBL1XR1F-box-like/WD repeat-containing protein TBL1XR1 isoform X1. (519 aa)
TGS1Trimethylguanosine synthase isoform X1. (885 aa)
PRDX6Peroxiredoxin-6 isoform X1. (263 aa)
LOC112551887Protein SCO2 homolog, mitochondrial. (275 aa)
UBBpolyubiquitin-B. (233 aa)
CCSSuperoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (255 aa)
NCOR1Nuclear receptor corepressor 1 isoform X1. (2560 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10. (157 aa)
NME9Thioredoxin domain-containing protein 6 isoform X1. (178 aa)
NUDT2Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] isoform X1. (202 aa)
PSMA5Proteasome endopeptidase complex. (183 aa)
UBXN7UBX domain-containing protein 7. (460 aa)
COX3Cytochrome c oxidase subunit 3; Subunits I, II and III form the functional core of the enzyme complex. (261 aa)
COX2Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. (229 aa)
SOD2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (224 aa)
NPVFpro-FMRFamide-related neuropeptide VF. (190 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
COILCoilin. (540 aa)
KLHL17Kelch-like protein 17. (588 aa)
TXNRD3Thioredoxin reductase 3. (604 aa)
PSMD626S proteasome non-ATPase regulatory subunit 6. (317 aa)
LOC102374986Histone-arginine methyltransferase CARM1-like isoform X1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (532 aa)
BACH2Transcription regulator protein BACH2 isoform X1. (832 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
PSMD1426S proteasome non-ATPase regulatory subunit 14 isoform X1. (310 aa)
PRDX3Thioredoxin-dependent peroxide reductase, mitochondrial. (227 aa)
LOC102384186Hemoglobin subunit alpha; Belongs to the globin family. (142 aa)
BACH1Transcription regulator protein BACH1 isoform X1. (763 aa)
LOC102383053Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
HMOX1Heme oxygenase 1. (299 aa)
LOC102374307Cytochrome c oxidase subunit 7C, mitochondrial. (63 aa)
PRDX2Peroxiredoxin-2. (273 aa)
LOC102380429Cytochrome c oxidase subunit 7B, mitochondrial. (79 aa)
TXNThioredoxin; Belongs to the thioredoxin family. (105 aa)
COX1Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (525 aa)
PSMD726S proteasome non-ATPase regulatory subunit 7. (297 aa)
NCOA6LOW QUALITY PROTEIN: nuclear receptor coactivator 6. (2007 aa)
SRXN1Sulfiredoxin. (118 aa)
PSMF1Proteasome inhibitor PI31 subunit. (190 aa)
HMOX2Heme oxygenase 2. (314 aa)
LOC102387300Butyrophilin subfamily 2 member A2-like isoform X1. (217 aa)
SIN3APaired amphipathic helix protein Sin3a isoform X1. (1279 aa)
LOC102380167Sestrin-3-like isoform X1. (457 aa)
GPX3Glutathione peroxidase; Belongs to the glutathione peroxidase family. (221 aa)
SKP1S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa)
LRPPRCLeucine-rich PPR motif-containing protein, mitochondrial. (1356 aa)
LOC102378286Cytochrome c oxidase subunit 4 isoform 1, mitochondrial. (170 aa)
CUL3Cullin-3 isoform X1; Belongs to the cullin family. (746 aa)
PSMA6Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (382 aa)
LOC102387169Cytochrome c oxidase subunit 7A2, mitochondrial. (89 aa)
UBCpolyubiquitin-C. (381 aa)
PSMD926S proteasome non-ATPase regulatory subunit 9 isoform X1. (205 aa)
FAM45AProtein FAM45A isoform X1. (354 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (528 aa)
KEAP1Kelch-like ECH-associated protein 1 isoform X1. (589 aa)
FBXL17F-box/LRR-repeat protein 17. (237 aa)
PSMB3Proteasome subunit beta. (290 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
PDIA2Protein disulfide-isomerase A2. (533 aa)
PSMB1Proteasome subunit beta. (240 aa)
CUNH1orf198Uncharacterized protein C1orf198 homolog. (197 aa)
LOC102383279Cytochrome c oxidase assembly protein COX11, mitochondrial. (171 aa)
GPX8Glutathione peroxidase; Belongs to the glutathione peroxidase family. (209 aa)
PSMA8Proteasome subunit alpha type. (249 aa)
PRDX1Peroxiredoxin-1. (199 aa)
PSMC526S proteasome regulatory subunit 8; Belongs to the AAA ATPase family. (411 aa)
BLVRBFlavin reductase (NADPH). (209 aa)
SOD3Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (244 aa)
PSMC626S proteasome regulatory subunit 10B; Belongs to the AAA ATPase family. (373 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4 isoform X1. (352 aa)
KLHL18Kelch-like protein 18. (602 aa)
LOC102367872Cytochrome c oxidase subunit 7A-related protein, mitochondrial isoform X1. (142 aa)
NFE2L2Nuclear factor erythroid 2-related factor 2. (586 aa)
NCF1Neutrophil cytosol factor 1. (389 aa)
PRDX5Peroxiredoxin-5, mitochondrial. (123 aa)
TBL1XF-box-like/WD repeat-containing protein TBL1X isoform X1. (523 aa)
LOC102381860Proteasome subunit beta. (277 aa)
LOC102372937Hemoglobin subunit beta-like; Belongs to the globin family. (147 aa)
LOC102379476Proteasome subunit beta type-9-like. (280 aa)
KXD1kxDL motif-containing protein 1. (176 aa)
PSMC326S proteasome regulatory subunit 6A; Belongs to the AAA ATPase family. (422 aa)
RBX1E3 ubiquitin-protein ligase RBX1 isoform X1. (108 aa)
PSMB6Proteasome subunit beta. (227 aa)
GPX1Glutathione peroxidase; Belongs to the glutathione peroxidase family. (183 aa)
FABP1Fatty acid-binding protein, liver. (127 aa)
GSRGlutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (440 aa)
PSME2Proteasome activator complex subunit 2. (242 aa)
Your Current Organism:
Alligator sinensis
NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494
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