STRINGSTRING
PNPLA2 PNPLA2 MYBPC3 MYBPC3 GFPT1 GFPT1 LOC102372584 LOC102372584 RYR2 RYR2 PFKFB3 PFKFB3 BTK BTK CPT2 CPT2 DLAT DLAT NCF4 NCF4 SHMT1 SHMT1 CACNA2D1 CACNA2D1 GOT2 GOT2 SLC25A20 SLC25A20 CACNA1C CACNA1C NCOR2 NCOR2 TSHR TSHR CIRBP CIRBP LOC102386394 LOC102386394 TNNI1 TNNI1 FASN FASN LIPE LIPE PHKG2 PHKG2 PLIN2 PLIN2 MYF6 MYF6 GLS GLS CD3E CD3E AGXT2 AGXT2 CPT1B CPT1B OGDH OGDH COMP COMP ELOVL6 ELOVL6 PKM PKM ABCG8 ABCG8 PDHB PDHB PKP2 PKP2 GSK3A GSK3A DGAT1 DGAT1 TNNC2 TNNC2 PSAT1 PSAT1 CD8A CD8A VWF VWF APOB APOB MYLK3 MYLK3 AQP2 AQP2 PDK4 PDK4 PKLR PKLR CD36 CD36 IL7R IL7R MYL3 MYL3 PDHA1 PDHA1 KLHL40 KLHL40 DGAT2 DGAT2 ZBED1 ZBED1 PYGL PYGL PYGB PYGB TRH TRH MEF2C MEF2C MYL1 MYL1 NCF2 NCF2 CACNB4 CACNB4 CSRP3 CSRP3 PLPP1 PLPP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PNPLA2Patatin-like phospholipase domain-containing protein 2. (483 aa)
MYBPC3Myosin-binding protein C, cardiac-type isoform X1. (1277 aa)
GFPT1Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 isoform X1. (621 aa)
LOC102372584Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (1316 aa)
RYR2Ryanodine receptor 2 isoform X1. (5130 aa)
PFKFB36-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 3 isoform X4. (531 aa)
BTKTyrosine-protein kinase. (803 aa)
CPT2Carnitine O-palmitoyltransferase 2, mitochondrial isoform X1; Belongs to the carnitine/choline acetyltransferase family. (729 aa)
DLATAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (543 aa)
NCF4Neutrophil cytosol factor 4 isoform X1. (355 aa)
SHMT1Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (615 aa)
CACNA2D1Voltage-dependent calcium channel subunit alpha-2/delta-1. (863 aa)
GOT2Aspartate aminotransferase. (460 aa)
SLC25A20Mitochondrial carnitine/acylcarnitine carrier protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (352 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2175 aa)
NCOR2Nuclear receptor corepressor 2 isoform X1. (2608 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (717 aa)
CIRBPCold-inducible RNA-binding protein isoform X1. (173 aa)
LOC102386394Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (390 aa)
TNNI1Troponin I, slow skeletal muscle. (166 aa)
FASNFatty acid synthase isoform X1. (2993 aa)
LIPELOW QUALITY PROTEIN: hormone-sensitive lipase. (702 aa)
PHKG2Phosphorylase b kinase gamma catalytic chain, liver/testis isoform. (331 aa)
PLIN2Perilipin; Belongs to the perilipin family. (444 aa)
MYF6Myogenic factor 6 isoform X1. (553 aa)
GLSGlutaminase kidney isoform, mitochondrial isoform X1. (578 aa)
CD3ET-cell surface glycoprotein CD3 epsilon chain. (187 aa)
AGXT2Alanine--glyoxylate aminotransferase 2, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (494 aa)
CPT1BCarnitine O-palmitoyltransferase 1, muscle isoform isoform X1; Belongs to the carnitine/choline acetyltransferase family. (773 aa)
OGDHLOW QUALITY PROTEIN: 2-oxoglutarate dehydrogenase, mitochondrial. (1032 aa)
COMPCartilage oligomeric matrix protein. (774 aa)
ELOVL6Elongation of very long chain fatty acids protein. (215 aa)
PKMPyruvate kinase; Belongs to the pyruvate kinase family. (530 aa)
ABCG8ATP-binding cassette sub-family G member 8. (677 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (249 aa)
PKP2Plakophilin-2 isoform X1. (780 aa)
GSK3AGlycogen synthase kinase-3 alpha. (298 aa)
DGAT1O-acyltransferase. (410 aa)
TNNC2Troponin C, skeletal muscle. (160 aa)
PSAT1Phosphoserine aminotransferase. (370 aa)
CD8AT-cell surface glycoprotein CD8 alpha chain. (223 aa)
VWFVon Willebrand factor isoform X1. (2822 aa)
APOBApolipoprotein B-100. (3654 aa)
MYLK3Myosin light chain kinase 3 isoform X1. (878 aa)
AQP2Aquaporin-2; Belongs to the MIP/aquaporin (TC 1.A.8) family. (274 aa)
PDK4Protein-serine/threonine kinase. (436 aa)
PKLRPyruvate kinase; Belongs to the pyruvate kinase family. (531 aa)
CD36Platelet glycoprotein 4; Belongs to the CD36 family. (470 aa)
IL7RInterleukin-7 receptor subunit alpha. (464 aa)
MYL3Myosin light chain 3. (193 aa)
PDHA1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (400 aa)
KLHL40Kelch-like protein 40. (619 aa)
DGAT2Diacylglycerol O-acyltransferase 2. (358 aa)
ZBED1Zinc finger BED domain-containing protein 1. (695 aa)
PYGLAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (864 aa)
PYGBAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (839 aa)
TRHPro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. (262 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform X1. (483 aa)
MYL1Myosin light chain 1/3, skeletal muscle isoform isoform X1. (196 aa)
NCF2Neutrophil cytosol factor 2 isoform X1. (529 aa)
CACNB4LOW QUALITY PROTEIN: voltage-dependent L-type calcium channel subunit beta-4. (498 aa)
CSRP3Cysteine and glycine-rich protein 3. (194 aa)
PLPP1Phospholipid phosphatase 1. (292 aa)
Your Current Organism:
Alligator sinensis
NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.