STRINGSTRING
PKP2 PKP2 MYF6 MYF6 PLIN2 PLIN2 PHKG2 PHKG2 LIPE LIPE FASN FASN TNNI1 TNNI1 LOC102386394 LOC102386394 CIRBP CIRBP TSHR TSHR NCOR2 NCOR2 CACNA1C CACNA1C SLC25A20 SLC25A20 GOT2 GOT2 CACNA2D1 CACNA2D1 SHMT1 SHMT1 NCF4 NCF4 DLAT DLAT CPT2 CPT2 BTK BTK PFKFB3 PFKFB3 RYR2 RYR2 LOC102372584 LOC102372584 GFPT1 GFPT1 MYBPC3 MYBPC3 PLPP1 PLPP1 CSRP3 CSRP3 CACNB4 CACNB4 NCF2 NCF2 MYL1 MYL1 MEF2C MEF2C TRH TRH PYGB PYGB PYGL PYGL ZBED1 ZBED1 DGAT2 DGAT2 KLHL40 KLHL40 PDHA1 PDHA1 MYL3 MYL3 IL7R IL7R CD36 CD36 PKLR PKLR PDK4 PDK4 AQP2 AQP2 MYLK3 MYLK3 APOB APOB VWF VWF PNPLA2 PNPLA2 CD8A CD8A PSAT1 PSAT1 TNNC2 TNNC2 DGAT1 DGAT1 GSK3A GSK3A PDHB PDHB ABCG8 ABCG8 PKM PKM ELOVL6 ELOVL6 COMP COMP OGDH OGDH CPT1B CPT1B AGXT2 AGXT2 CD3E CD3E GLS GLS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PKP2Plakophilin-2 isoform X1. (780 aa)
MYF6Myogenic factor 6 isoform X1. (553 aa)
PLIN2Perilipin; Belongs to the perilipin family. (444 aa)
PHKG2Phosphorylase b kinase gamma catalytic chain, liver/testis isoform. (331 aa)
LIPELOW QUALITY PROTEIN: hormone-sensitive lipase. (702 aa)
FASNFatty acid synthase isoform X1. (2993 aa)
TNNI1Troponin I, slow skeletal muscle. (166 aa)
LOC102386394Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (390 aa)
CIRBPCold-inducible RNA-binding protein isoform X1. (173 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (717 aa)
NCOR2Nuclear receptor corepressor 2 isoform X1. (2608 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2175 aa)
SLC25A20Mitochondrial carnitine/acylcarnitine carrier protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (352 aa)
GOT2Aspartate aminotransferase. (460 aa)
CACNA2D1Voltage-dependent calcium channel subunit alpha-2/delta-1. (863 aa)
SHMT1Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (615 aa)
NCF4Neutrophil cytosol factor 4 isoform X1. (355 aa)
DLATAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (543 aa)
CPT2Carnitine O-palmitoyltransferase 2, mitochondrial isoform X1; Belongs to the carnitine/choline acetyltransferase family. (729 aa)
BTKTyrosine-protein kinase. (803 aa)
PFKFB36-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 3 isoform X4. (531 aa)
RYR2Ryanodine receptor 2 isoform X1. (5130 aa)
LOC102372584Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (1316 aa)
GFPT1Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 isoform X1. (621 aa)
MYBPC3Myosin-binding protein C, cardiac-type isoform X1. (1277 aa)
PLPP1Phospholipid phosphatase 1. (292 aa)
CSRP3Cysteine and glycine-rich protein 3. (194 aa)
CACNB4LOW QUALITY PROTEIN: voltage-dependent L-type calcium channel subunit beta-4. (498 aa)
NCF2Neutrophil cytosol factor 2 isoform X1. (529 aa)
MYL1Myosin light chain 1/3, skeletal muscle isoform isoform X1. (196 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform X1. (483 aa)
TRHPro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. (262 aa)
PYGBAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (839 aa)
PYGLAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (864 aa)
ZBED1Zinc finger BED domain-containing protein 1. (695 aa)
DGAT2Diacylglycerol O-acyltransferase 2. (358 aa)
KLHL40Kelch-like protein 40. (619 aa)
PDHA1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (400 aa)
MYL3Myosin light chain 3. (193 aa)
IL7RInterleukin-7 receptor subunit alpha. (464 aa)
CD36Platelet glycoprotein 4; Belongs to the CD36 family. (470 aa)
PKLRPyruvate kinase; Belongs to the pyruvate kinase family. (531 aa)
PDK4Protein-serine/threonine kinase. (436 aa)
AQP2Aquaporin-2; Belongs to the MIP/aquaporin (TC 1.A.8) family. (274 aa)
MYLK3Myosin light chain kinase 3 isoform X1. (878 aa)
APOBApolipoprotein B-100. (3654 aa)
VWFVon Willebrand factor isoform X1. (2822 aa)
PNPLA2Patatin-like phospholipase domain-containing protein 2. (483 aa)
CD8AT-cell surface glycoprotein CD8 alpha chain. (223 aa)
PSAT1Phosphoserine aminotransferase. (370 aa)
TNNC2Troponin C, skeletal muscle. (160 aa)
DGAT1O-acyltransferase. (410 aa)
GSK3AGlycogen synthase kinase-3 alpha. (298 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (249 aa)
ABCG8ATP-binding cassette sub-family G member 8. (677 aa)
PKMPyruvate kinase; Belongs to the pyruvate kinase family. (530 aa)
ELOVL6Elongation of very long chain fatty acids protein. (215 aa)
COMPCartilage oligomeric matrix protein. (774 aa)
OGDHLOW QUALITY PROTEIN: 2-oxoglutarate dehydrogenase, mitochondrial. (1032 aa)
CPT1BCarnitine O-palmitoyltransferase 1, muscle isoform isoform X1; Belongs to the carnitine/choline acetyltransferase family. (773 aa)
AGXT2Alanine--glyoxylate aminotransferase 2, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (494 aa)
CD3ET-cell surface glycoprotein CD3 epsilon chain. (187 aa)
GLSGlutaminase kidney isoform, mitochondrial isoform X1. (578 aa)
Your Current Organism:
Alligator sinensis
NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494
Server load: low (34%) [HD]