STRINGSTRING
PLCB2 PLCB2 PIP4K2A PIP4K2A INPP5E INPP5E IMPA1 IMPA1 PI4KA PI4KA MTMR7 MTMR7 SYNJ2 SYNJ2 PIP4K2B PIP4K2B PIK3CG PIK3CG PIK3CD PIK3CD FIG4 FIG4 PLCZ1 PLCZ1 PLCD3 PLCD3 ITPKA ITPKA PLCG2 PLCG2 LOC102378320 LOC102378320 PLCD1 PLCD1 MTMR8 MTMR8 ISYNA1 ISYNA1 PIK3C2G PIK3C2G MIOX MIOX INPP1 INPP1 IMPA2 IMPA2 PIP4K2C PIP4K2C ITPK1 ITPK1 LOC102368100 LOC102368100 TPI1 TPI1 PIK3C2B PIK3C2B PIK3CB PIK3CB PIP5KL1 PIP5KL1 PLCB4 PLCB4 PTEN PTEN LOC102368895 LOC102368895 LOC102384994 LOC102384994 INPP4A INPP4A INPP5D INPP5D INPP5K INPP5K PLCG1 PLCG1 LOC102369174 LOC102369174 MTMR14 MTMR14 MTMR3 MTMR3 PLCE1 PLCE1 PLCB3 PLCB3 INPPL1 INPPL1 LOC112548809 LOC112548809 PIK3CA PIK3CA MTMR6 MTMR6 MTMR2 MTMR2 LOC102375443 LOC102375443 INPP5F INPP5F ALDH6A1 ALDH6A1 SACM1L SACM1L PIK3C3 PIK3C3 PLCB1 PLCB1 PIP5K1B PIP5K1B PI4K2B PI4K2B PIK3C2A PIK3C2A IPPK IPPK MTMR1 MTMR1 MTM1 MTM1 PIP5K1C PIP5K1C OCRL OCRL PIKFYVE PIKFYVE INPP4B INPP4B PLCH2 PLCH2 SYNJ1 SYNJ1 PIP5K1A PIP5K1A INPP5B INPP5B IPMK IPMK PI4K2A PI4K2A ITPKB ITPKB PLCH1 PLCH1 MTMR4 MTMR4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1207 aa)
PIP4K2APhosphatidylinositol 5-phosphate 4-kinase type-2 alpha isoform X1. (347 aa)
INPP5E72 kDa inositol polyphosphate 5-phosphatase. (618 aa)
IMPA1Inositol-1-monophosphatase. (278 aa)
PI4KAPhosphatidylinositol 4-kinase alpha isoform X1; Belongs to the PI3/PI4-kinase family. (2044 aa)
MTMR7Myotubularin-related protein 7. (660 aa)
SYNJ2Synaptojanin-2 isoform X1. (1459 aa)
PIP4K2BPhosphatidylinositol 5-phosphate 4-kinase type-2 beta. (370 aa)
PIK3CGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1117 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1046 aa)
FIG4Polyphosphoinositide phosphatase isoform X1. (908 aa)
PLCZ1Phosphoinositide phospholipase C. (634 aa)
PLCD3Phosphoinositide phospholipase C. (754 aa)
ITPKAKinase; Belongs to the inositol phosphokinase (IPK) family. (333 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
LOC102378320Phosphatidylinositol 4-kinase beta; Belongs to the PI3/PI4-kinase family. (343 aa)
PLCD1Phosphoinositide phospholipase C. (771 aa)
MTMR8Myotubularin-related protein 8. (632 aa)
ISYNA1Inositol-3-phosphate synthase 1. (432 aa)
PIK3C2GPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma; Belongs to the PI3/PI4-kinase family. (1010 aa)
MIOXInositol oxygenase. (286 aa)
INPP1Inositol polyphosphate 1-phosphatase. (376 aa)
IMPA2Inositol-1-monophosphatase. (274 aa)
PIP4K2CPhosphatidylinositol 5-phosphate 4-kinase type-2 gamma. (342 aa)
ITPK1Inositol-tetrakisphosphate 1-kinase. (407 aa)
LOC102368100Type I inositol 1,4,5-trisphosphate 5-phosphatase-like. (157 aa)
TPI1Triosephosphate isomerase. (248 aa)
PIK3C2BPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta isoform X1; Belongs to the PI3/PI4-kinase family. (1637 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
PIP5KL1Phosphatidylinositol 4-phosphate 5-kinase-like protein 1 isoform X1. (440 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
PTENannotation not available (206 aa)
LOC1023688951-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1295 aa)
LOC102384994Uncharacterized protein LOC102384994. (469 aa)
INPP4AType I inositol 3,4-bisphosphate 4-phosphatase isoform X1. (976 aa)
INPP5DPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform X1. (1209 aa)
INPP5KInositol polyphosphate 5-phosphatase K. (457 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1282 aa)
LOC102369174LOW QUALITY PROTEIN: phosphatidylinositol 4-kinase beta-like. (511 aa)
MTMR14Myotubularin-related protein 14. (513 aa)
MTMR3Myotubularin-related protein 3 isoform X1. (1224 aa)
PLCE11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1. (2319 aa)
PLCB3Phosphoinositide phospholipase C. (795 aa)
INPPL1Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2. (1267 aa)
LOC112548809Inositol-tetrakisphosphate 1-kinase-like. (195 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
MTMR6LOW QUALITY PROTEIN: myotubularin-related protein 6. (629 aa)
MTMR2Myotubularin-related protein 2 isoform X1. (574 aa)
LOC102375443Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2-like isoform X1. (1114 aa)
INPP5FPhosphatidylinositide phosphatase SAC2 isoform X1. (1135 aa)
ALDH6A1Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial. (559 aa)
SACM1LPhosphatidylinositide phosphatase SAC1 isoform X3. (484 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (895 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1183 aa)
PIP5K1BPhosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1. (710 aa)
PI4K2BPhosphatidylinositol 4-kinase type 2-beta. (462 aa)
PIK3C2ALOW QUALITY PROTEIN: phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha; Belongs to the PI3/PI4-kinase family. (1712 aa)
IPPKInositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). (498 aa)
MTMR1Myotubularin-related protein 1 isoform X1. (571 aa)
MTM1Myotubularin isoform X2. (612 aa)
PIP5K1CPhosphatidylinositol 4-phosphate 5-kinase type-1 gamma. (675 aa)
OCRLInositol polyphosphate 5-phosphatase OCRL-1 isoform X1. (836 aa)
PIKFYVE1-phosphatidylinositol 3-phosphate 5-kinase. (2126 aa)
INPP4BType II inositol 3,4-bisphosphate 4-phosphatase. (1055 aa)
PLCH2Phosphoinositide phospholipase C. (1601 aa)
SYNJ1Synaptojanin-1. (1589 aa)
PIP5K1APhosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X1. (648 aa)
INPP5BType II inositol 1,4,5-trisphosphate 5-phosphatase isoform X3. (921 aa)
IPMKKinase; Belongs to the inositol phosphokinase (IPK) family. (366 aa)
PI4K2ALOW QUALITY PROTEIN: phosphatidylinositol 4-kinase type 2-alpha. (391 aa)
ITPKBKinase; Belongs to the inositol phosphokinase (IPK) family. (396 aa)
PLCH1Phosphoinositide phospholipase C. (1667 aa)
MTMR4Myotubularin-related protein 4 isoform X3. (1171 aa)
Your Current Organism:
Alligator sinensis
NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.