STRINGSTRING
MAPK8 MAPK8 SEC24A SEC24A HSP90AB1 HSP90AB1 SEC61B SEC61B MBTPS1 MBTPS1 LMAN1 LMAN1 LOC102388487 LOC102388487 PPP1R15A PPP1R15A LOC102372433 LOC102372433 UBXN4 UBXN4 UBE2J2 UBE2J2 SEL1L SEL1L CALR CALR XBP1 XBP1 MAN1B1 MAN1B1 SKP1 SKP1 DDOST DDOST EIF2S1 EIF2S1 SEC24C SEC24C RAD23A RAD23A SEC61A1 SEC61A1 CANX CANX SEC61G SEC61G HSP90B1 HSP90B1 ERN1 ERN1 HSP90AA1 HSP90AA1 MAN1A2 MAN1A2 SEC24D SEC24D CAPN11 CAPN11 DNAJC1 DNAJC1 AMFR AMFR BAG1 BAG1 BCAP31 BCAP31 DNAJA1 DNAJA1 LOC102385096 LOC102385096 DNAJB11 DNAJB11 DERL1 DERL1 SEC61A2 SEC61A2 DERL2 DERL2 MAN1A1 MAN1A1 DNAJC10 DNAJC10 CAPN2 CAPN2 SAR1A SAR1A STT3B STT3B BAK1 BAK1 SEC24B SEC24B NPLOC4 NPLOC4 ATF4 ATF4 SSR4 SSR4 SSR1 SSR1 UBE2D1 UBE2D1 NFE2L2 NFE2L2 ERN2 ERN2 UBE2G2 UBE2G2 CRYAB CRYAB RBX1 RBX1 CRYAA CRYAA LOC102368981 LOC102368981 SYVN1 SYVN1 SEC31A SEC31A MAP3K5 MAP3K5 SEC23B SEC23B BCL2 BCL2 LOC102370120 LOC102370120 UBQLN4 UBQLN4 SSR2 SSR2 DNAJB2 DNAJB2 DNAJB1 DNAJB1 CAPN1 CAPN1 DDIT3 DDIT3 LOC102371352 LOC102371352 P4HB P4HB DNAJC5B DNAJC5B BAX BAX HSPA2 HSPA2 RNF185 RNF185 EIF2AK2 EIF2AK2 TUSC3 TUSC3 ERLEC1 ERLEC1 PDIA6 PDIA6 DNAJC5 DNAJC5 PRKN PRKN SEC13 SEC13 CKAP4 CKAP4 UBE2J1 UBE2J1 TRAF2 TRAF2 STUB1 STUB1 LOC102368266 LOC102368266 UFD1 UFD1 NGLY1 NGLY1 LOC102383381 LOC102383381 EIF2AK1 EIF2AK1 RRBP1 RRBP1 SSR3 SSR3 UBXN2A UBXN2A MBTPS2 MBTPS2 PDIA4 PDIA4 PDIA3 PDIA3 SEC63 SEC63 LOC102379400 LOC102379400 SAR1B SAR1B RPN2 RPN2 EDEM3 EDEM3 LOC102387990 LOC102387990 MOGS MOGS OS9 OS9 MAP2K7 MAP2K7 ATF6B ATF6B HSPBP1 HSPBP1 HYOU1 HYOU1 WFS1 WFS1 ATF6 ATF6 HSPA5 HSPA5 UBXN6 UBXN6 RPN1 RPN1 LOC102374542 LOC102374542 MARCH6 MARCH6 MAN1C1 MAN1C1 EIF2AK4 EIF2AK4 SELENOS SELENOS SEC62 SEC62 ERP29 ERP29 UGGT2 UGGT2 SVIP SVIP TRAM1 TRAM1 HSPA8 HSPA8 SEC23A SEC23A DNAJC3 DNAJC3 LOC102378524 LOC102378524 STT3A STT3A RAD23B RAD23B UBQLN1 UBQLN1 HSPA4L HSPA4L YOD1 YOD1 PRKCSH PRKCSH SIL1 SIL1 BAG2 BAG2 UBE2D2 UBE2D2 ERO1A ERO1A PLAA PLAA VCP VCP SEC31B SEC31B EDEM1 EDEM1 MAPK9 MAPK9 UGGT1 UGGT1 CUL1 CUL1 TXNDC5 TXNDC5 CALR3 CALR3 DNAJB12 DNAJB12 SEL1L2 SEL1L2 UBE2G1 UBE2G1 HERPUD1 HERPUD1 UBE4B UBE4B NSFL1C NSFL1C ATXN3 ATXN3 GANAB GANAB HSPH1 HSPH1 ERO1B ERO1B PREB PREB LOC102369165 LOC102369165 DNAJA2 DNAJA2 UBXN1 UBXN1 UBE2D3 UBE2D3
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAPK8Mitogen-activated protein kinase. (427 aa)
SEC24AProtein transport protein Sec24A isoform X1. (1101 aa)
HSP90AB1Heat shock protein HSP 90-beta. (729 aa)
SEC61BProtein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (96 aa)
MBTPS1Membrane-bound transcription factor site-1 protease isoform X1. (1060 aa)
LMAN1Protein ERGIC-53. (460 aa)
LOC102388487F-box only protein 6. (186 aa)
PPP1R15AProtein phosphatase 1 regulatory subunit 15A. (532 aa)
LOC102372433F-box only protein 2 isoform X1. (257 aa)
UBXN4UBX domain-containing protein 4. (551 aa)
UBE2J2Ubiquitin-conjugating enzyme E2 J2. (259 aa)
SEL1LProtein sel-1 homolog 1. (800 aa)
CALRCalreticulin. (412 aa)
XBP1X-box-binding protein 1. (137 aa)
MAN1B1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (668 aa)
SKP1S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa)
DDOSTDolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...] (407 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit 1. (315 aa)
SEC24CProtein transport protein Sec24C isoform X1. (1186 aa)
RAD23AUV excision repair protein RAD23 homolog A isoform X1. (363 aa)
SEC61A1Protein transport protein Sec61 subunit alpha. (476 aa)
CANXLOW QUALITY PROTEIN: calnexin. (615 aa)
SEC61GProtein transport protein Sec61 subunit gamma. (68 aa)
HSP90B1Endoplasmin. (427 aa)
ERN1Serine/threonine-protein kinase/endoribonuclease IRE1 isoform X1. (1008 aa)
HSP90AA1Heat shock protein HSP 90-alpha. (728 aa)
MAN1A2alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (673 aa)
SEC24DProtein transport protein Sec24D. (1038 aa)
CAPN11Calpain-11; Belongs to the peptidase C2 family. (705 aa)
DNAJC1dnaJ homolog subfamily C member 1. (524 aa)
AMFRE3 ubiquitin-protein ligase AMFR isoform X2. (474 aa)
BAG1BAG family molecular chaperone regulator 1. (215 aa)
BCAP31B-cell receptor-associated protein 31 isoform X2. (314 aa)
DNAJA1dnaJ homolog subfamily A member 1. (397 aa)
LOC102385096Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (216 aa)
DNAJB11dnaJ homolog subfamily B member 11. (358 aa)
DERL1Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (252 aa)
SEC61A2LOW QUALITY PROTEIN: protein transport protein Sec61 subunit alpha. (474 aa)
DERL2Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (252 aa)
MAN1A1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (471 aa)
DNAJC10LOW QUALITY PROTEIN: dnaJ homolog subfamily C member 10. (808 aa)
CAPN2Calpain-2 catalytic subunit; Belongs to the peptidase C2 family. (700 aa)
SAR1AGTP-binding protein SAR1a; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
STT3BDolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B. (740 aa)
BAK1Bcl-2 homologous antagonist/killer isoform X1. (251 aa)
SEC24BProtein transport protein Sec24B. (1193 aa)
NPLOC4Nuclear protein localization protein 4 homolog isoform X1. (609 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4 isoform X1. (352 aa)
SSR4Translocon-associated protein subunit delta isoform X1. (175 aa)
SSR1Translocon-associated protein subunit alpha isoform X1. (295 aa)
UBE2D1Ubiquitin-conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (124 aa)
NFE2L2Nuclear factor erythroid 2-related factor 2. (586 aa)
ERN2Serine/threonine-protein kinase/endoribonuclease IRE2 isoform X1. (958 aa)
UBE2G2Ubiquitin-conjugating enzyme E2 G2; Belongs to the ubiquitin-conjugating enzyme family. (165 aa)
CRYABAlpha-crystallin B chain; Belongs to the small heat shock protein (HSP20) family. (119 aa)
RBX1E3 ubiquitin-protein ligase RBX1 isoform X1. (108 aa)
CRYAAAlpha-crystallin A chain; Belongs to the small heat shock protein (HSP20) family. (173 aa)
LOC102368981Heat shock 70 kDa protein II-like; Belongs to the heat shock protein 70 family. (638 aa)
SYVN1E3 ubiquitin-protein ligase synoviolin. (627 aa)
SEC31AProtein transport protein Sec31A isoform X1. (1264 aa)
MAP3K5LOW QUALITY PROTEIN: mitogen-activated protein kinase kinase kinase 5. (1200 aa)
SEC23BProtein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (770 aa)
BCL2Apoptosis regulator Bcl-2 isoform X1. (214 aa)
LOC102370120dnaJ homolog subfamily C member 5-like. (123 aa)
UBQLN4Ubiquilin-4. (596 aa)
SSR2Translocon-associated protein subunit beta; TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. (183 aa)
DNAJB2dnaJ homolog subfamily B member 2. (214 aa)
DNAJB1dnaJ homolog subfamily B member 1. (336 aa)
CAPN1Calpain-1 catalytic subunit; Belongs to the peptidase C2 family. (714 aa)
DDIT3DNA damage-inducible transcript 3 protein. (184 aa)
LOC102371352Ubiquilin-1-like. (465 aa)
P4HBProtein disulfide-isomerase. (427 aa)
DNAJC5BdnaJ homolog subfamily C member 5B. (196 aa)
BAXApoptosis regulator BAX isoform X1. (253 aa)
HSPA2LOW QUALITY PROTEIN: heat shock-related 70 kDa protein 2; Belongs to the heat shock protein 70 family. (645 aa)
RNF185E3 ubiquitin-protein ligase RNF185. (194 aa)
EIF2AK2Interferon-induced, double-stranded RNA-activated protein kinase. (536 aa)
TUSC3Tumor suppressor candidate 3. (291 aa)
ERLEC1Endoplasmic reticulum lectin 1. (417 aa)
PDIA6Protein disulfide-isomerase A6; Belongs to the protein disulfide isomerase family. (447 aa)
DNAJC5dnaJ homolog subfamily C member 5. (198 aa)
PRKNRBR-type E3 ubiquitin transferase. (504 aa)
SEC13Protein SEC13 homolog; Belongs to the WD repeat SEC13 family. (300 aa)
CKAP4Cytoskeleton-associated protein 4. (429 aa)
UBE2J1Ubiquitin-conjugating enzyme E2 J1. (332 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (553 aa)
STUB1E3 ubiquitin-protein ligase CHIP. (232 aa)
LOC102368266LOW QUALITY PROTEIN: heat shock 70 kDa protein 1A-like; Belongs to the heat shock protein 70 family. (616 aa)
UFD1Ubiquitin recognition factor in ER-associated degradation protein 1. (302 aa)
NGLY1peptide-N(4)-(N-acetyl-beta- glucosaminyl)asparagine amidase. (649 aa)
LOC102383381alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (795 aa)
EIF2AK1Eukaryotic translation initiation factor 2-alpha kinase 1. (663 aa)
RRBP1Ribosome-binding protein 1 isoform X1. (994 aa)
SSR3Translocon-associated protein subunit gamma. (133 aa)
UBXN2AUBX domain-containing protein 2A isoform X1. (258 aa)
MBTPS2Membrane-bound transcription factor site-2 protease isoform X1. (494 aa)
PDIA4Protein disulfide-isomerase. (653 aa)
PDIA3Protein disulfide-isomerase. (566 aa)
SEC63Translocation protein SEC63 homolog. (743 aa)
LOC102379400dnaJ homolog subfamily C member 3-like. (413 aa)
SAR1BGTP-binding protein SAR1b; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
RPN2Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (642 aa)
EDEM3alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (945 aa)
LOC102387990Translocating chain-associated membrane protein 1-like isoform X1. (288 aa)
MOGSMannosyl-oligosaccharide glucosidase. (639 aa)
OS9Protein OS-9. (575 aa)
MAP2K7Dual specificity mitogen-activated protein kinase kinase 7 isoform X1. (349 aa)
ATF6BCyclic AMP-dependent transcription factor ATF-6 beta. (603 aa)
HSPBP1Hsp70-binding protein 1. (280 aa)
HYOU1Hypoxia up-regulated protein 1. (1022 aa)
WFS1Wolframin. (879 aa)
ATF6Cyclic AMP-dependent transcription factor ATF-6 alpha. (670 aa)
HSPA5LOW QUALITY PROTEIN: endoplasmic reticulum chaperone BiP; Belongs to the heat shock protein 70 family. (655 aa)
UBXN6UBX domain-containing protein 6 isoform X1. (441 aa)
RPN1Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (662 aa)
LOC102374542Mitogen-activated protein kinase. (464 aa)
MARCH6E3 ubiquitin-protein ligase MARCH6. (983 aa)
MAN1C1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (458 aa)
EIF2AK4eIF-2-alpha kinase GCN2. (1676 aa)
SELENOSSelenoprotein S. (188 aa)
SEC62Translocation protein SEC62. (365 aa)
ERP29Endoplasmic reticulum resident protein 29. (217 aa)
UGGT2UDP-glucose:glycoprotein glucosyltransferase 2 isoform X1. (1559 aa)
SVIPSmall VCP/p97-interacting protein. (69 aa)
TRAM1Translocating chain-associated membrane protein 1. (288 aa)
HSPA8Heat shock cognate 71 kDa protein isoform X1; Belongs to the heat shock protein 70 family. (658 aa)
SEC23AProtein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (765 aa)
DNAJC3dnaJ homolog subfamily C member 3. (623 aa)
LOC102378524alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (594 aa)
STT3ADolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A isoform X1. (705 aa)
RAD23BUV excision repair protein RAD23 homolog B isoform X1. (468 aa)
UBQLN1Ubiquilin-1. (534 aa)
HSPA4LLOW QUALITY PROTEIN: heat shock 70 kDa protein 4L. (813 aa)
YOD1Ubiquitin thioesterase OTU1. (265 aa)
PRKCSHLOW QUALITY PROTEIN: glucosidase 2 subunit beta. (595 aa)
SIL1Nucleotide exchange factor SIL1 isoform X1. (510 aa)
BAG2LOW QUALITY PROTEIN: BAG family molecular chaperone regulator 2. (221 aa)
UBE2D2Ubiquitin-conjugating enzyme E2 D2; Belongs to the ubiquitin-conjugating enzyme family. (221 aa)
ERO1AERO1-like protein alpha. (459 aa)
PLAAPhospholipase A-2-activating protein isoform X1. (782 aa)
VCPTransitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family. (761 aa)
SEC31BProtein transport protein Sec31B. (1228 aa)
EDEM1alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (457 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
UGGT1UDP-glucose:glycoprotein glucosyltransferase 1 isoform X1. (1595 aa)
CUL1Cullin-1 isoform X1; Belongs to the cullin family. (778 aa)
TXNDC5Thioredoxin domain-containing protein 5 isoform X2; Belongs to the protein disulfide isomerase family. (337 aa)
CALR3Calreticulin. (442 aa)
DNAJB12LOW QUALITY PROTEIN: dnaJ homolog subfamily B member 12. (392 aa)
SEL1L2Protein sel-1 homolog 2. (606 aa)
UBE2G1Ubiquitin-conjugating enzyme E2 G1; Belongs to the ubiquitin-conjugating enzyme family. (188 aa)
HERPUD1Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein. (297 aa)
UBE4BUbiquitin conjugation factor E4 B isoform X1. (1347 aa)
NSFL1CNSFL1 cofactor p47. (396 aa)
ATXN3Ataxin-3 isoform X1. (381 aa)
GANABNeutral alpha-glucosidase AB; Belongs to the glycosyl hydrolase 31 family. (859 aa)
HSPH1Heat shock protein 105 kDa isoform X1. (760 aa)
ERO1BERO1-like protein beta. (454 aa)
PREBProlactin regulatory element-binding protein. (429 aa)
LOC102369165dnaJ homolog subfamily A member 1-like. (332 aa)
DNAJA2dnaJ homolog subfamily A member 2. (420 aa)
UBXN1UBX domain-containing protein 1. (208 aa)
UBE2D3Ubiquitin-conjugating enzyme E2 D3 isoform X1; Belongs to the ubiquitin-conjugating enzyme family. (119 aa)
Your Current Organism:
Alligator sinensis
NCBI taxonomy Id: 38654
Other names: A. sinensis, Chinese alligator, MNHN 6494
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