node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NIS_0006 | NIS_0010 | NIS_0006 | NIS_0010 | Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | Succinate dehydrogenase/fumarate reductase, iron-sulfur protein. | 0.990 |
NIS_0006 | NIS_0688 | NIS_0006 | NIS_0688 | Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | Succinate dehydrogenase/fumarate reductase, subunit C. | 0.653 |
NIS_0006 | NIS_0689 | NIS_0006 | NIS_0689 | Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | Succinate dehydrogenase/fumarate reductase, iron-sulfur protein. | 0.990 |
NIS_0006 | NIS_0836 | NIS_0006 | NIS_0836 | Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | Fumarate/tartrate hydratase, alpha subunit; EC 4.2.1.32/EC 4.2.1.2, FumA/TtdA. | 0.733 |
NIS_0006 | NIS_0837 | NIS_0006 | NIS_0837 | Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | Fumarate/tartrate hydratase, beta subunit; EC 4.2.1.32/EC 4.2.1.2, FumB/TtdB. | 0.733 |
NIS_0006 | mdh | NIS_0006 | NIS_0835 | Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.604 |
NIS_0006 | sucC | NIS_0006 | NIS_0838 | Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | succinyl-CoA synthase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.784 |
NIS_0006 | sucD | NIS_0006 | NIS_0839 | Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | succinyl-CoA synthase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.822 |
NIS_0010 | NIS_0006 | NIS_0010 | NIS_0006 | Succinate dehydrogenase/fumarate reductase, iron-sulfur protein. | Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | 0.990 |
NIS_0010 | NIS_0688 | NIS_0010 | NIS_0688 | Succinate dehydrogenase/fumarate reductase, iron-sulfur protein. | Succinate dehydrogenase/fumarate reductase, subunit C. | 0.556 |
NIS_0010 | NIS_0690 | NIS_0010 | NIS_0690 | Succinate dehydrogenase/fumarate reductase, iron-sulfur protein. | Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.991 |
NIS_0010 | NIS_0836 | NIS_0010 | NIS_0836 | Succinate dehydrogenase/fumarate reductase, iron-sulfur protein. | Fumarate/tartrate hydratase, alpha subunit; EC 4.2.1.32/EC 4.2.1.2, FumA/TtdA. | 0.699 |
NIS_0010 | NIS_0837 | NIS_0010 | NIS_0837 | Succinate dehydrogenase/fumarate reductase, iron-sulfur protein. | Fumarate/tartrate hydratase, beta subunit; EC 4.2.1.32/EC 4.2.1.2, FumB/TtdB. | 0.699 |
NIS_0010 | mdh | NIS_0010 | NIS_0835 | Succinate dehydrogenase/fumarate reductase, iron-sulfur protein. | Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.618 |
NIS_0010 | sucC | NIS_0010 | NIS_0838 | Succinate dehydrogenase/fumarate reductase, iron-sulfur protein. | succinyl-CoA synthase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.815 |
NIS_0010 | sucD | NIS_0010 | NIS_0839 | Succinate dehydrogenase/fumarate reductase, iron-sulfur protein. | succinyl-CoA synthase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.863 |
NIS_0688 | NIS_0006 | NIS_0688 | NIS_0006 | Succinate dehydrogenase/fumarate reductase, subunit C. | Succinate dehydrogenase/fumarate reductase, flavoprotein subunit. | 0.653 |
NIS_0688 | NIS_0010 | NIS_0688 | NIS_0010 | Succinate dehydrogenase/fumarate reductase, subunit C. | Succinate dehydrogenase/fumarate reductase, iron-sulfur protein. | 0.556 |
NIS_0688 | NIS_0689 | NIS_0688 | NIS_0689 | Succinate dehydrogenase/fumarate reductase, subunit C. | Succinate dehydrogenase/fumarate reductase, iron-sulfur protein. | 0.993 |
NIS_0688 | NIS_0690 | NIS_0688 | NIS_0690 | Succinate dehydrogenase/fumarate reductase, subunit C. | Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.991 |