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glmM glmM lspA lspA murE murE murD murD mraY mraY NIS_0354 NIS_0354 alr alr NIS_0751 NIS_0751 NIS_0784 NIS_0784 mltG mltG murA murA NIS_1022 NIS_1022 NIS_1026 NIS_1026 NIS_1027 NIS_1027 NIS_1028 NIS_1028 rsmH rsmH NIS_1031 NIS_1031 ftsA ftsA ftsZ ftsZ NIS_1093 NIS_1093 ddlA ddlA glmU glmU murC murC murI murI NIS_1529 NIS_1529 ftsW ftsW murG murG murB murB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (445 aa)
lspALipoprotein signal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. (143 aa)
murEUDP-N-acetylmuramoylananine-D-glutamate-2, 6-diaminopimelate ligase; Belongs to the MurCDEF family. MurE subfamily. (430 aa)
murDUDP-N-acetylmuramoylalanine--D-glutamate ligase. (394 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (354 aa)
NIS_0354Conserved hypothetical protein. (310 aa)
alrAlanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (332 aa)
NIS_0751Cell shape-determining protein RodA; Belongs to the SEDS family. (367 aa)
NIS_0784Peptidoglycan glycosyltransferase. (595 aa)
mltGConserved hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (319 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (420 aa)
NIS_1022Conserved hypothetical protein. (127 aa)
NIS_1026Conserved hypothetical protein. (92 aa)
NIS_1027Cation:multidrug efflux pump; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1027 aa)
NIS_1028Conserved hypothetical protein. (94 aa)
rsmHS-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (302 aa)
NIS_1031Conserved hypothetical protein. (490 aa)
ftsACell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. (450 aa)
ftsZCell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (371 aa)
NIS_1093UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanine ligase. (474 aa)
ddlAD-alanine-D-alanine ligase; Cell wall formation. (342 aa)
glmUGlucosamine-1-phosphate N-acetyltransferase/UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the tra [...] (430 aa)
murCUDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (436 aa)
murIGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (253 aa)
NIS_1529Cell division protein FtsI. (581 aa)
ftsWCell division protein FtsW; Belongs to the SEDS family. (391 aa)
murGUndecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (333 aa)
murBUDP-N-acetylmuramate dehydrogenase; Cell wall formation. (257 aa)
Your Current Organism:
Nitratiruptor sp. SB1552
NCBI taxonomy Id: 387092
Other names: N. sp. SB155-2, Nitratiruptor sp. SB155-2
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