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| | secD | Preprotein translocase subunit D; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (520 aa) |
| | yajC | Preprotein translocase subunit YajC; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. (91 aa) |
| | tatA | Twin-arginine translocation system protein, TatA/E family; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (78 aa) |
| | ffh | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual componen [...] (452 aa) |
| | NIS_1535 | ABC transporter, ATP-binding protein. (216 aa) |
| | NIS_1560 | Conserved hypothetical protein. (154 aa) |
| | NIS_1561 | Fimbrial protein. (159 aa) |
| | NIS_1562 | General secretory pathway protein F. (412 aa) |
| | NIS_1563 | General secretory pathway protein E. (560 aa) |
| | NIS_1566 | General secretory pathway protein D. (495 aa) |
| | NIS_1353 | Conserved hypothetical protein. (303 aa) |
| | NIS_1352 | Conserved hypothetical protein. (235 aa) |
| | NIS_1349 | Conserved hypothetical protein. (212 aa) |
| | NIS_1320 | Conserved hypothetical protein. (171 aa) |
| | NIS_1218 | Biopolymer transport protein, ExbB/TolQ family. (186 aa) |
| | NIS_1217 | Biopolymer transport protein, ExbD/TolR family. (129 aa) |
| | NIS_1215 | Tol biopolymer transport system component TolB. (407 aa) |
| | tatC | Twin-arginine translocation system component TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. (246 aa) |
| | tatB | Twin-arginine translocation system component TatB; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. (125 aa) |
| | ftsY | Signal recognition particle receptor FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. (286 aa) |
| | NIS_1011 | General secretory pathway protein F. (412 aa) |
| | NIS_1010 | General secretory pathway protein E. (576 aa) |
| | NIS_1006 | General secretory pathway protein D. (507 aa) |
| | yidC | Conserved hypothetical protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. (528 aa) |
| | NIS_0880 | Conserved hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. (105 aa) |
| | NIS_0855 | Conserved hypothetical protein. (125 aa) |
| | secA | Preprotein translocase subunit A; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. (863 aa) |
| | NIS_0829 | Conserved hypothetical protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). (170 aa) |
| | NIS_0720 | Conserved hypothetical protein. (278 aa) |
| | NIS_0654 | Conserved hypothetical protein. (229 aa) |
| | flhB | Flagellar biosynthetic protein FlhB; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family. (351 aa) |
| | fliR | Flagellar biosynthetic protein FliR; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family. (255 aa) |
| | NIS_1402 | Type I secretion system membrane fusion protein. (428 aa) |
| | fliQ | Flagellar biosynthetic protein FliQ; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family. (89 aa) |
| | fliP | Flagellar transport protein FliP; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family. (236 aa) |
| | fliI | Flagellar-specific ATP synthase FliI. (431 aa) |
| | NIS_0616 | Flagellar biosynthesis protein FlhF. (391 aa) |
| | flhA | Flagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. (695 aa) |
| | NIS_0511 | Conserved hypothetical protein. (493 aa) |
| | NIS_0335 | Conserved hypothetical protein. (117 aa) |
| | NIS_0334 | Conserved hypothetical protein. (148 aa) |
| | NIS_0333 | Conserved hypothetical protein. (152 aa) |
| | secE | Preprotein translocase subunit E; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. (59 aa) |
| | NIS_1403 | Type I secretion system ATPase. (569 aa) |
| | NIS_1423 | Biopolymer transport protein, ExbD/TolR family. (131 aa) |
| | NIS_1424 | Biopolymer transport protein, ExbB/TolQ family. (144 aa) |
| | secF | Preprotein translocase subunit F; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (324 aa) |
| | NIS_0201 | Conserved hypothetical protein. (558 aa) |
| | NIS_1571 | Hypothetical protein; Similar to general secretion pathway protein G. (300 aa) |
| | NIS_1572 | Conserved hypothetical protein. (218 aa) |
| | NIS_1674 | Antimicrobial peptide ABC transporter, permease. (397 aa) |
| | NIS_0200 | Hypothetical protein. (865 aa) |
| | tig | Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. (437 aa) |
| | NIS_0112 | ABC transporter, ATP-binding protein. (236 aa) |
| | NIS_0072 | Multiple antibiotic transporter, MarC family. (214 aa) |
| | secY | Preprotein translocase subunit Y; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (420 aa) |
| | NIS_1687 | Conserved hypothetical protein. (571 aa) |
| | NIS_1791 | Heme d1 biosynthesis protein NirF; Nitrite reductase (NO-forming). (376 aa) |
| | NIS_1841 | Preprotein translocase subunit G; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (113 aa) |
