STRINGSTRING
ftsH ftsH NIS_1403 NIS_1403 NIS_0008 NIS_0008 NIS_0018 NIS_0018 NIS_0066 NIS_0066 NIS_0112 NIS_0112 NIS_0287 NIS_0287 dnaB dnaB NIS_0349 NIS_0349 ruvB ruvB clpA clpA pilT pilT clpX clpX pstB pstB NIS_0588 NIS_0588 fliI fliI NIS_0736 NIS_0736 ftsE ftsE recN recN NIS_0826 NIS_0826 NIS_0851 NIS_0851 NIS_0866 NIS_0866 clpB clpB hslU hslU NIS_1010 NIS_1010 sufC sufC NIS_1034 NIS_1034 NIS_1038 NIS_1038 radA radA dnaA dnaA NIS_1070 NIS_1070 NIS_1397 NIS_1397 NIS_1080 NIS_1080 NIS_1102 NIS_1102 NIS_1175 NIS_1175 atpD atpD lon lon NIS_1782 NIS_1782 rgy rgy NIS_1725 NIS_1725 NIS_1672 NIS_1672 recA recA NIS_1593 NIS_1593 NIS_1565 NIS_1565 NIS_1563 NIS_1563 NIS_1535 NIS_1535 NIS_1522 NIS_1522 dnaX dnaX rho rho
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ftsHCell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (660 aa)
NIS_1403Type I secretion system ATPase. (569 aa)
NIS_0008Circadian clock protein KaiC. (462 aa)
NIS_0018Sulfate ABC transporter, ATP-binding protein. (330 aa)
NIS_0066ATPase, AAA family. (391 aa)
NIS_0112ABC transporter, ATP-binding protein. (236 aa)
NIS_0287ATPase, AAA family. (576 aa)
dnaBReplicative DNA helicase DnaB; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (471 aa)
NIS_0349Mn2+/Zn2+ ABC transporter, ATP-binding protein. (241 aa)
ruvBHolliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (335 aa)
clpAATP-dependent Clp protease, ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. (729 aa)
pilTTwitching motility protein PilT. (393 aa)
clpXATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (409 aa)
pstBPhosphate ABC transporter, ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (261 aa)
NIS_0588ATPase, AAA family. (304 aa)
fliIFlagellar-specific ATP synthase FliI. (431 aa)
NIS_0736Multidrug ABC transporter, ATP-binding protein. (583 aa)
ftsECell division ATP-binding protein FtsE. (224 aa)
recNDNA repair protein RecN; May be involved in recombinational repair of damaged DNA. (507 aa)
NIS_0826Cell division protein FtsK. (702 aa)
NIS_0851ABC transporter, ATP-binding protein. (240 aa)
NIS_0866Oligopeptide ABC transporter, ATP-binding protein. (199 aa)
clpBATP-dependent Clp protease, ATP-binding subunit ClpB; Belongs to the ClpA/ClpB family. (862 aa)
hslUATP-dependent protease HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. (443 aa)
NIS_1010General secretory pathway protein E. (576 aa)
sufCFe-S cluster assembly ATPase SufC. (249 aa)
NIS_1034ABC transporter, ATP-binding protein. (254 aa)
NIS_1038ABC transport system ATP-binding protein. (647 aa)
radADNA repair protein RadA/Sms; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (445 aa)
dnaAChromosome replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (443 aa)
NIS_1070Hypothetical protein. (786 aa)
NIS_1397ABC transporter, ATP-binding protein. (390 aa)
NIS_1080ATP-dependent zinc metalloproteinase; Belongs to the AAA ATPase family. (552 aa)
NIS_1102Multidrug ABC transporter, ATP-binding protein and permease. (569 aa)
NIS_1175Twitching motility protein PilT. (354 aa)
atpDF0F1-type ATP synthase, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (469 aa)
lonATP-dependent Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (805 aa)
NIS_1782ABC transporter, ATP-binding protein. (212 aa)
rgyReverse gyrase Rgy; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family. (1118 aa)
NIS_1725Multidrug ABC transporter. (539 aa)
NIS_1672Antimicrobial peptide ABC transporter, ATP-binding protein. (220 aa)
recADNA recombination protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (344 aa)
NIS_1593Sulfonate/nitrate ABC transporter, ATP-binding protein. (243 aa)
NIS_1565Conserved hypothetical protein. (263 aa)
NIS_1563General secretory pathway protein E. (560 aa)
NIS_1535ABC transporter, ATP-binding protein. (216 aa)
NIS_1522ABC transporter, ATP-binding protein. (234 aa)
dnaXDNA polymerase III, gamma/tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (512 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (454 aa)
Your Current Organism:
Nitratiruptor sp. SB1552
NCBI taxonomy Id: 387092
Other names: N. sp. SB155-2, Nitratiruptor sp. SB155-2
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.