(31 nodes) Precatalytic spliceosome network (Lupinus angustifolius)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TanjilG_18843	Uncharacterized protein. (448 aa)
	TanjilG_24610	Sm domain-containing protein. (79 aa)
	LSM8-2	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (87 aa)
	TanjilG_05853	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (139 aa)
	TanjilG_02734	PRP38_assoc domain-containing protein. (384 aa)
	TanjilG_32625	PRP38_assoc domain-containing protein. (568 aa)
	TanjilG_29584	RRM domain-containing protein. (124 aa)
	TanjilG_16771	Uncharacterized protein. (514 aa)
	TanjilG_08498	Small nuclear ribonucleoprotein Sm D2. (104 aa)
	TanjilG_12325	Small nuclear ribonucleoprotein Sm D3; Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. (131 aa)
	TanjilG_09719	Small nuclear ribonucleoprotein Sm D3; Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. (131 aa)
	LSM8	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (98 aa)
	TanjilG_09467	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (88 aa)
	TanjilG_13757	Uncharacterized protein. (928 aa)
	TanjilG_02570	Small nuclear ribonucleoprotein G. (79 aa)
	TanjilG_06754	PSP domain-containing protein. (580 aa)
	TanjilG_32179	Uncharacterized protein. (390 aa)
	TanjilG_24987	PSP domain-containing protein. (581 aa)
	TanjilG_21936	Small nuclear ribonucleoprotein Sm D2. (104 aa)
	LSM3-2	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (99 aa)
	TanjilG_11482	Sm-like protein LSM2; Component of LSM protein complexes, which are involved in RNA processing. (93 aa)
	TanjilG_05411	Small nuclear ribonucleoprotein Sm D3; Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. (117 aa)
	TanjilG_32450	Splicing factor subunit; Belongs to the SF3B5 family. (87 aa)
	TanjilG_11475	Small nuclear ribonucleoprotein Sm D1; Involved in splicing regulation. Facilitates post- transcriptional gene silencing (PTGS) by limiting the degradation of transgene aberrant RNAs by the RNA quality control (RQC) machinery, thus favoring their entry into cytoplasmic siRNA bodies where they can trigger PTGS. Does not participate in the production of small RNAs. Belongs to the snRNP core protein family. (176 aa)
	TanjilG_12070	Sm domain-containing protein. (79 aa)
	TanjilG_21684	PSP domain-containing protein. (581 aa)
	TanjilG_01895	Uncharacterized protein. (110 aa)
	TanjilG_24087	PRP38_assoc domain-containing protein. (426 aa)
	LSM3	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (96 aa)
	TanjilG_31128	Small nuclear ribonucleoprotein G. (79 aa)
	TanjilG_31560	Small nuclear ribonucleoprotein Sm D2. (104 aa)

Your Current Organism:

Lupinus angustifolius

NCBI taxonomy Id: 3871
Other names: L. angustifolius, Lupinus angustifolius L., narrow-leaved blue lupine

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LSM3	LSM3-2	A0A1J7GEM2	A0A1J7I1A3	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.900
LSM3	LSM8	A0A1J7GEM2	A0A4P1QSD4	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.998
LSM3	LSM8-2	A0A1J7GEM2	A0A4P1REW9	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.990
LSM3	TanjilG_01895	A0A1J7GEM2	A0A1J7GVX2	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Uncharacterized protein.	0.969
LSM3	TanjilG_02570	A0A1J7GEM2	A0A394DEL3	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Small nuclear ribonucleoprotein G.	0.980
LSM3	TanjilG_02734	A0A1J7GEM2	A0A4P1RBD6	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	PRP38_assoc domain-containing protein.	0.671
LSM3	TanjilG_05411	A0A1J7GEM2	A0A1J7HPT1	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Small nuclear ribonucleoprotein Sm D3; Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.	0.946
LSM3	TanjilG_05853	A0A1J7GEM2	A0A4P1RE82	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.	0.911
LSM3	TanjilG_06754	A0A1J7GEM2	A0A394DEF7	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	PSP domain-containing protein.	0.841
LSM3	TanjilG_08498	A0A1J7GEM2	A0A4P1R031	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Small nuclear ribonucleoprotein Sm D2.	0.981
LSM3	TanjilG_09467	A0A1J7GEM2	A0A394DG15	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.	0.996
LSM3	TanjilG_09719	A0A1J7GEM2	A0A4P1QWV0	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Small nuclear ribonucleoprotein Sm D3; Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.	0.946
LSM3	TanjilG_11475	A0A1J7GEM2	A0A1J7H1Z4	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Small nuclear ribonucleoprotein Sm D1; Involved in splicing regulation. Facilitates post- transcriptional gene silencing (PTGS) by limiting the degradation of transgene aberrant RNAs by the RNA quality control (RQC) machinery, thus favoring their entry into cytoplasmic siRNA bodies where they can trigger PTGS. Does not participate in the production of small RNAs. Belongs to the snRNP core protein family.	0.933
LSM3	TanjilG_11482	A0A1J7GEM2	A0A1J7HY78	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Sm-like protein LSM2; Component of LSM protein complexes, which are involved in RNA processing.	0.999
LSM3	TanjilG_12070	A0A1J7GEM2	A0A1J7GY01	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Sm domain-containing protein.	0.933
LSM3	TanjilG_12325	A0A1J7GEM2	A0A4P1QY10	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Small nuclear ribonucleoprotein Sm D3; Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.	0.946
LSM3	TanjilG_16771	A0A1J7GEM2	A0A4P1R0I3	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Uncharacterized protein.	0.609
LSM3	TanjilG_21684	A0A1J7GEM2	A0A1J7GW76	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	PSP domain-containing protein.	0.841
LSM3	TanjilG_21936	A0A1J7GEM2	A0A1J7IB82	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Small nuclear ribonucleoprotein Sm D2.	0.981
LSM3	TanjilG_24610	A0A1J7GEM2	A0A4P1RK82	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Sm domain-containing protein.	0.933