STRINGSTRING
LVIS_1037 LVIS_1037 LVIS_1038 LVIS_1038 LVIS_1050 LVIS_1050 LVIS_1128 LVIS_1128 LVIS_1129 LVIS_1129 LVIS_1141 LVIS_1141 LVIS_1149 LVIS_1149 LVIS_1173 LVIS_1173 ackA-2 ackA-2 LVIS_1216 LVIS_1216 LVIS_1221 LVIS_1221 cshB cshB LVIS_1225 LVIS_1225 LVIS_1251 LVIS_1251 LVIS_1256 LVIS_1256 ezrA ezrA rpsD rpsD LVIS_1263 LVIS_1263 LVIS_1292 LVIS_1292 LVIS_1332 LVIS_1332 LVIS_1336 LVIS_1336 rpsB rpsB LVIS_1363 LVIS_1363 rnz rnz rpsO rpsO rpsT rpsT LVIS_1396 LVIS_1396 LVIS_1409 LVIS_1409 LVIS_1436 LVIS_1436 LVIS_1443 LVIS_1443 LVIS_1462 LVIS_1462 LVIS_1487 LVIS_1487 LVIS_1503 LVIS_1503 LVIS_1520 LVIS_1520 LVIS_1556 LVIS_1556 LVIS_1557 LVIS_1557 LVIS_1568 LVIS_1568 LVIS_1573 LVIS_1573 LVIS_1580 LVIS_1580 LVIS_1600 LVIS_1600 ackA-3 ackA-3 LVIS_1605 LVIS_1605 LVIS_1606 LVIS_1606 LVIS_1607 LVIS_1607 pduL pduL LVIS_1609 LVIS_1609 LVIS_1610 LVIS_1610 LVIS_1611 LVIS_1611 LVIS_1613 LVIS_1613 LVIS_1614 LVIS_1614 LVIS_1615 LVIS_1615 LVIS_1616 LVIS_1616 LVIS_1617 LVIS_1617 rpsI rpsI rplM rplM truA truA rplQ rplQ rpsK rpsK rpsM rpsM rpmJ rpmJ adk adk rplO rplO rpmD rpmD rpsE rpsE rplR rplR rplF rplF rpsH rpsH rpsZ rpsZ rplE rplE rplX rplX rplN rplN rpsQ rpsQ rpmC rpmC rplP rplP rpsC rpsC rplV rplV rpsS rpsS rplB rplB rplW rplW rplD rplD rplC rplC rpsJ rpsJ rpsG rpsG rpsL rpsL LVIS_1711 LVIS_1711 LVIS_1719 LVIS_1719 LVIS_1741 LVIS_1741 LVIS_1751 LVIS_1751 LVIS_1753 LVIS_1753 LVIS_1754 LVIS_1754 LVIS_1810 LVIS_1810 LVIS_1857 LVIS_1857 LVIS_1870 LVIS_1870 LVIS_1880 LVIS_1880 LVIS_1881 LVIS_1881 rpmH rpmH LVIS_2301 LVIS_2301 LVIS_2269 LVIS_2269 LVIS_2235 LVIS_2235 LVIS_2233 LVIS_2233 tyrS-2 tyrS-2 LVIS_2190 LVIS_2190 LVIS_2172 LVIS_2172 LVIS_2165 LVIS_2165 LVIS_2136 LVIS_2136 LVIS_2111 LVIS_2111 LVIS_2100 LVIS_2100 LVIS_2063 LVIS_2063 ychF ychF ubiX ubiX LVIS_1979 LVIS_1979 LVIS_1970 LVIS_1970 sbcD sbcD LVIS_1912 LVIS_1912 LVIS_1911 LVIS_1911 LVIS_1909 LVIS_1909 rtpR rtpR LVIS_1897 LVIS_1897 recF recF gyrB gyrB rpsF rpsF rpsR rpsR LVIS_0020 LVIS_0020 LVIS_0033 LVIS_0033 LVIS_0050 LVIS_0050 LVIS_0051 LVIS_0051 LVIS_0076 LVIS_0076 LVIS_0096 LVIS_0096 LVIS_0100 LVIS_0100 LVIS_0116 LVIS_0116 LVIS_0128 LVIS_0128 ackA ackA LVIS_0192 LVIS_0192 LVIS_0198 LVIS_0198 LVIS_0216 LVIS_0216 LVIS_0217 LVIS_0217 LVIS_0232 LVIS_0232 LVIS_0245 LVIS_0245 LVIS_0253 LVIS_0253 LVIS_0261 LVIS_0261 LVIS_0263 LVIS_0263 LVIS_0278 LVIS_0278 LVIS_0321 LVIS_0321 LVIS_0325 LVIS_0325 LVIS_0334 LVIS_0334 LVIS_0339 LVIS_0339 rpsN rpsN tyrS tyrS LVIS_0441 LVIS_0441 LVIS_0450 LVIS_0450 LVIS_0452 LVIS_0452 rnmV rnmV ispE ispE LVIS_0482 LVIS_0482 rpmE2 rpmE2 cshA cshA LVIS_0520 LVIS_0520 LVIS_0525 LVIS_0525 LVIS_0535 LVIS_0535 mrnC mrnC rpmG1 rpmG1 rplK rplK rplA rplA rplJ rplJ rplL rplL LVIS_0594 LVIS_0594 tadA tadA LVIS_0601 LVIS_0601 recR recR LVIS_0603 LVIS_0603 hpf hpf dtd dtd nfo nfo rpsU rpsU ybeY ybeY LVIS_0750 LVIS_0750 recO recO dnaG dnaG LVIS_0774 LVIS_0774 LVIS_0777 LVIS_0777 LVIS_0779 LVIS_0779 LVIS_0795 LVIS_0795 topA topA parE parE nth nth fhs fhs LVIS_0836 LVIS_0836 LVIS_0838 LVIS_0838 LVIS_0854 LVIS_0854 fni fni LVIS_0864 LVIS_0864 LVIS_0900 LVIS_0900 LVIS_0931 LVIS_0931 rplS rplS rpsP rpsP LVIS_0946 LVIS_0946 LVIS_0947 LVIS_0947 smc smc rpmB rpmB priA priA LVIS_0972 LVIS_0972 LVIS_0975 LVIS_0975 rpmA rpmA rplU rplU LVIS_0998 LVIS_0998 rpmG2 rpmG2 udk udk rpmF rpmF nadD nadD LVIS_1031 LVIS_1031 rplT rplT rpmI rpmI
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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LVIS_1037Replicative DNA helicase loader DnaI. (308 aa)
LVIS_1038Replicative DNA helicase loader DnaB. (456 aa)
LVIS_1050Thiol-disulfide isomerase and thioredoxin. (110 aa)
LVIS_1128Replicative DNA helicase. (414 aa)
LVIS_1129Hypothetical protein. (250 aa)
LVIS_1141Transcriptional regulator, xre family. (138 aa)
LVIS_1149Metal-dependent hydrolase of the beta-lactamase superfamily III. (246 aa)
LVIS_1173RNA binding protein (S1 domain). (129 aa)
ackA-2Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (396 aa)
LVIS_1216Thiol-disulfide isomerase and thioredoxin; Belongs to the thioredoxin family. (105 aa)
LVIS_1221RNase H-like ribonuclease; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. (145 aa)
cshBSuperfamily II DNA and RNA helicase; Probable DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures. (452 aa)
LVIS_1225Phosphoesterase, DHH family protein. (321 aa)
LVIS_1251DNA repair protein. (220 aa)
LVIS_1256Cysteine sulfinate desulfinase/cysteine desulfurase related enzyme. (381 aa)
ezrANegative regulator of septation ring formation; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. (576 aa)
rpsDSSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (201 aa)
LVIS_1263Recombination protein MgsA. (425 aa)
LVIS_1292UDP-N-acetylmuramyl tripeptide synthase. (449 aa)
LVIS_1332FMN adenylyltransferase / riboflavin kinase; Belongs to the ribF family. (315 aa)
LVIS_1336LSU ribosomal protein L7AE. (100 aa)
rpsBSSU ribosomal protein S2P; Belongs to the universal ribosomal protein uS2 family. (267 aa)
LVIS_1363hydroxymethylglutaryl-CoA synthase. (389 aa)
rnzMetal-dependent hydrolase of the beta-lactamase superfamily III; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (317 aa)
rpsOSSU ribosomal protein S15P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. (89 aa)
rpsTSSU ribosomal protein S20P; Binds directly to 16S ribosomal RNA. (84 aa)
LVIS_1396Deoxycytidylate deaminase. (159 aa)
LVIS_1409Acetoin dehydrogenase complex, E1 component, beta subunit. (325 aa)
LVIS_1436Cysteine sulfinate desulfinase/cysteine desulfurase related enzyme. (398 aa)
LVIS_1443Cell division protein, S4-like domain. (259 aa)
LVIS_1462Copper resistance protein; Belongs to the CutC family. (207 aa)
LVIS_1487DNA repair exonuclease. (404 aa)
LVIS_1503Dipeptidase A. Cysteine peptidase. MEROPS family C69. (469 aa)
LVIS_1520Deoxynucleoside kinase. (215 aa)
LVIS_1556Cation transport ATPase. (868 aa)
LVIS_1557Dipeptidase A. Cysteine peptidase. MEROPS family C69. (477 aa)
LVIS_1568Hypothetical protein. (81 aa)
LVIS_1573Hypothetical protein. (283 aa)
LVIS_1580Superfamily II DNA and RNA helicase. (441 aa)
LVIS_1600Propanediol utilization protein. (114 aa)
ackA-3Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (395 aa)
LVIS_1605Adenosylcobalamin-dependent diol dehydratase gamma subunit; Belongs to the Cob(I)alamin adenosyltransferase family. (191 aa)
LVIS_1606Propanediol utilization protein; Similar to carboxysome shell protein CcmL. (90 aa)
LVIS_1607Propanediol utilization protein. (173 aa)
pduLPropanediol utilization protein; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. (208 aa)
LVIS_1609Propanediol utilization protein; Similar to carboxysome shell protein CcmK. (96 aa)
LVIS_1610Propanediol utilization protein; Similar to carboxysome shell protein CcmK. (162 aa)
LVIS_1611Diol Dehydratase medium subunit. (117 aa)
LVIS_1613Propanediol dehydratase, small subunit. (175 aa)
LVIS_1614Diol Dehydratase medium subunit. (239 aa)
LVIS_1615Propanediol dehydratase, large subunit. (558 aa)
LVIS_1616Propanediol utilization protein. (238 aa)
LVIS_1617Propanediol utilization protein; Similar to carboxysome shell protein CcmK. (92 aa)
rpsISSU ribosomal protein S9P; Belongs to the universal ribosomal protein uS9 family. (130 aa)
rplMLSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (147 aa)
truAPseudouridylate synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (265 aa)
rplQLSU ribosomal protein L17P. (127 aa)
rpsKSSU ribosomal protein S11P; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (129 aa)
rpsMSSU ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (121 aa)
rpmJLSU ribosomal protein L36P; Belongs to the bacterial ribosomal protein bL36 family. (39 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (219 aa)
rplOLSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (144 aa)
rpmDLSU ribosomal protein L30P. (60 aa)
rpsESSU ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family. (167 aa)
rplRLSU ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (118 aa)
rplFLSU ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (178 aa)
rpsHSSU ribosomal protein S8P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (132 aa)
rpsZSSU ribosomal protein S14P; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site. (61 aa)
rplELSU ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (180 aa)
rplXLSU ribosomal protein L24P; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (103 aa)
rplNLSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (122 aa)
rpsQSSU ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (88 aa)
rpmCLSU ribosomal protein L29P; Belongs to the universal ribosomal protein uL29 family. (64 aa)
rplPLSU ribosomal protein L16P; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (144 aa)
rpsCSSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (219 aa)
rplVLSU ribosomal protein L22P; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). (118 aa)
rpsSSSU ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (91 aa)
rplBLSU ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (282 aa)
rplWLSU ribosomal protein L23P; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (95 aa)
rplDLSU ribosomal protein L4P; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (207 aa)
rplCLSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (216 aa)
rpsJSSU ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa)
rpsGSSU ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa)
rpsLSSU ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy. (137 aa)
LVIS_1711Deoxynucleoside kinase. (210 aa)
LVIS_1719Co/Zn/Cd efflux system component. (298 aa)
LVIS_1741Ribulose-5-phosphate 4-epimerase related epimerase and aldolase. (242 aa)
LVIS_1751ATP-dependent DNA helicase RecQ. (591 aa)
LVIS_1753Predicted dinucleotide-binding enzyme. (191 aa)
LVIS_1754Dipeptidase A. Cysteine peptidase. MEROPS family C69. (467 aa)
LVIS_1810Acetyltransferase, GNAT family. (143 aa)
LVIS_1857Acetyltransferase, GNAT family. (82 aa)
LVIS_1870Rad3-related DNA helicase. (788 aa)
LVIS_1880Uncharacterized membrane protein. (235 aa)
LVIS_1881Uncharacterized membrane protein. (229 aa)
rpmHLSU ribosomal protein L34P; Belongs to the bacterial ribosomal protein bL34 family. (44 aa)
LVIS_2301Acyl-CoA hydrolase. (174 aa)
LVIS_2269Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase related deacylase. (380 aa)
LVIS_2235ADP-ribosylglycohydrolase. (334 aa)
LVIS_2233Sugar kinase, ribokinase family; Belongs to the carbohydrate kinase PfkB family. (292 aa)
tyrS-2tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (418 aa)
LVIS_2190Predicted Co/Zn/Cd cation transporter; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. (325 aa)
LVIS_2172Esterase/lipase. (350 aa)
LVIS_2165Glycerol dehydrogenase. (369 aa)
LVIS_2136Transcriptional regulator, xre family. (120 aa)
LVIS_2111Recombination protein MgsA. (439 aa)
LVIS_2100Short-chain dehydrogenase of various substrate specificities; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (278 aa)
LVIS_2063Chromosome segregation DNA-binding protein; Belongs to the ParB family. (294 aa)
ychFPredicted GTPase, probable translation factor; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (366 aa)
ubiX3-polyprenyl-4-hydroxybenzoate decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (187 aa)
LVIS_1979Ethanolamine utilisation protein EutN. (88 aa)
LVIS_1970Double-stranded beta-helix related protein. (140 aa)
sbcDDNA repair exonuclease; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. (377 aa)
LVIS_1912NADPH:quinone reductase related Zn-dependent oxidoreductase. (337 aa)
LVIS_1911Electron transfer flavoprotein, alpha subunit. (321 aa)
LVIS_1909butyryl-CoA dehydrogenase. (372 aa)
rtpRRibonucleotide reductase, alpha subunit; Belongs to the class II ribonucleoside-triphosphate reductase family. (749 aa)
LVIS_1897ATP:cob(I)alamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. (177 aa)
recFDNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. (384 aa)
gyrBDNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (647 aa)
rpsFSSU ribosomal protein S6P; Binds together with S18 to 16S ribosomal RNA. (98 aa)
rpsRSSU ribosomal protein S18P; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (78 aa)
LVIS_0020Primary replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (462 aa)
LVIS_0033Metal-dependent hydrolase of the beta-lactamase superfamily I. (275 aa)
LVIS_0050Esterase/lipase. (240 aa)
LVIS_0051ADP-ribosylglycohydrolase. (314 aa)
LVIS_0076NADPH:quinone reductase related Zn-dependent oxidoreductase. (335 aa)
LVIS_0096Acetyltransferase, GNAT family. (146 aa)
LVIS_0100Hypothetical protein. (271 aa)
LVIS_0116Cation transport ATPase. (778 aa)
LVIS_01282-dehydro-3-deoxygluconokinase. (326 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (395 aa)
LVIS_0192Acetylornithine deacetylase. (390 aa)
LVIS_0198Predicted acetyltransferase. (177 aa)
LVIS_0216Nucleoside-diphosphate-sugar epimerase. (345 aa)
LVIS_0217Acetyltransferase, GNAT family. (147 aa)
LVIS_0232Esterase/lipase. (294 aa)
LVIS_0245tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (331 aa)
LVIS_0253Acetylornithine deacetylase. (411 aa)
LVIS_0261Cation transport ATPase. (915 aa)
LVIS_0263Dipeptidase A. Cysteine peptidase. MEROPS family C69. (473 aa)
LVIS_0278Adenosine deaminase. (347 aa)
LVIS_0321Methylated DNA-protein cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (172 aa)
LVIS_03252-dehydro-3-deoxygluconokinase. (322 aa)
LVIS_0334Thiol-disulfide isomerase and thioredoxin; Belongs to the thioredoxin family. (108 aa)
LVIS_0339Esterase/lipase. (284 aa)
rpsNSSU ribosomal protein S14P; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (89 aa)
tyrStyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (419 aa)
LVIS_04412-dehydro-3-deoxygluconokinase. (320 aa)
LVIS_0450Hydroxymethylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family. (420 aa)
LVIS_0452NAD-dependent protein deacetylase, SIR2 family. (232 aa)
rnmVRibonuclease M5; Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step. (190 aa)
ispE4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (284 aa)
LVIS_0482HD superfamily phosphohydrolase. (452 aa)
rpmE2LSU ribosomal protein L31P. (83 aa)
cshASuperfamily II DNA and RNA helicase; DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA-dependent ATPase activity; Belongs to the DEAD box helicase family. CshA subfamily. (523 aa)
LVIS_0520RNA binding protein (S1 domain). (181 aa)
LVIS_0525tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (340 aa)
LVIS_0535Predicted phosphohydrolase. (258 aa)
mrnCRibonuclease III family protein; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family. (135 aa)
rpmG1Ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. (49 aa)
rplKLSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (141 aa)
rplALSU ribosomal protein L1P; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (232 aa)
rplJLSU ribosomal protein L10P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (168 aa)
rplLLSU ribosomal protein L12P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (122 aa)
LVIS_05943-hydroxyacyl-CoA dehydrogenase. (304 aa)
tadAtRNA-adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (183 aa)
LVIS_0601Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection. (105 aa)
recRDNA replication and repair protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (199 aa)
LVIS_0603Hypothetical protein. (83 aa)
hpfSSU ribosomal protein S30P / sigma 54 modulation protein; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. (186 aa)
dtdD-Tyr-tRNAtyr deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (147 aa)
nfoEndonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (309 aa)
rpsUSSU ribosomal protein S21P; Belongs to the bacterial ribosomal protein bS21 family. (62 aa)
ybeYPredicted metal-dependent hydrolase; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (162 aa)
LVIS_0750Diacylglycerol kinase. (133 aa)
recODNA replication and repair protein RecO; Involved in DNA repair and RecF pathway recombination. (260 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (612 aa)
LVIS_0774ATP-dependent DNA helicase RecQ. (473 aa)
LVIS_0777SSU ribosomal protein S1P. (434 aa)
LVIS_0779Bacterial nucleoid protein Hbs; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (91 aa)
LVIS_0795Ras superfamily GTP-binding protein YlqF; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. (286 aa)
topADNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (703 aa)
parEDNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 2 subfamily. (655 aa)
nthEndonuclease III / DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (216 aa)
fhsFormate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. (551 aa)
LVIS_0836Ribonuclease HI. (134 aa)
LVIS_0838Predicted oxidoreductase. (200 aa)
LVIS_0854DNA replication protein DnaD. (231 aa)
fniIsopentenyl diphosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (345 aa)
LVIS_0864Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase related deacylase. (386 aa)
LVIS_0900Dipeptidase A. Cysteine peptidase. MEROPS family C69. (471 aa)
LVIS_09313-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (408 aa)
rplSLSU ribosomal protein L19P; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (118 aa)
rpsPSSU ribosomal protein S16P; Belongs to the bacterial ribosomal protein bS16 family. (91 aa)
LVIS_0946Predicted ATPase. (390 aa)
LVIS_0947Cation transport ATPase. (882 aa)
smcCondensin subunit Smc; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1183 aa)
rpmBLSU ribosomal protein L28P; Belongs to the bacterial ribosomal protein bL28 family. (61 aa)
priAReplication restart DNA helicase PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (805 aa)
LVIS_0972DNA repair ATPase; May be involved in recombinational repair of damaged DNA. (564 aa)
LVIS_0975Farnesyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. (300 aa)
rpmALSU ribosomal protein L27P; Belongs to the bacterial ribosomal protein bL27 family. (99 aa)
rplULSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (102 aa)
LVIS_0998Membrane-associated serine protease. (226 aa)
rpmG2Ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. (49 aa)
udkUridine kinase. (223 aa)
rpmFLSU ribosomal protein L32P; Belongs to the bacterial ribosomal protein bL32 family. (62 aa)
nadDNicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (210 aa)
LVIS_1031Predicted GTPase. (380 aa)
rplTLSU ribosomal protein L20P; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (119 aa)
rpmILSU ribosomal protein L35P; Belongs to the bacterial ribosomal protein bL35 family. (64 aa)
Your Current Organism:
Lactobacillus brevis
NCBI taxonomy Id: 387344
Other names: L. brevis ATCC 367, Lactobacillus brevis ATCC 367, Lactobacillus brevis str. ATCC 367, Lactobacillus brevis strain ATCC 367
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