STRINGSTRING
MGP MGP DHX36 DHX36 SNAI2 SNAI2 CALCR CALCR ENSGAGP00000000858 ENSGAGP00000000858 INPPL1 INPPL1 JUNB JUNB ECM1 ECM1 WNT3A WNT3A TP53INP2 TP53INP2 SOX8 SOX8 NAB2 NAB2 CLEC3B CLEC3B BMP2 BMP2 ENSGAGP00000005402 ENSGAGP00000005402 SMO SMO ENSGAGP00000006046 ENSGAGP00000006046 IHH IHH FGF18 FGF18 MMP9 MMP9 GATA1 GATA1 SMAD5 SMAD5 FSTL3 FSTL3 ENSGAGP00000006994 ENSGAGP00000006994 MSX2 MSX2 ENSGAGP00000007080 ENSGAGP00000007080 AHSG AHSG ENSGAGP00000008310 ENSGAGP00000008310 ENSGAGP00000008368 ENSGAGP00000008368 IMPAD1 IMPAD1 CREB3L1 CREB3L1 ENSGAGP00000008932 ENSGAGP00000008932 CBFB CBFB LGR4 LGR4 HAND2 HAND2 ENSGAGP00000009577 ENSGAGP00000009577 MMP14 MMP14 PHOSPHO2 PHOSPHO2 PEX7 PEX7 ENSGAGP00000010858 ENSGAGP00000010858 MAPK11 MAPK11 TNFSF11 TNFSF11 NPPC NPPC MAPK14 MAPK14 IGFBP5 IGFBP5 TMEM38B TMEM38B ERCC2 ERCC2 ENSGAGP00000012687 ENSGAGP00000012687 DLX5 DLX5 ADAR ADAR ENSGAGP00000013084 ENSGAGP00000013084 DHH DHH GPLD1 GPLD1 ENSGAGP00000013860 ENSGAGP00000013860 RUNX3 RUNX3 BMPR1B BMPR1B THBS3 THBS3 TMEM119 TMEM119 ENSGAGP00000015098 ENSGAGP00000015098 PKDCC PKDCC TGFB3 TGFB3 ATF4 ATF4 MESD MESD BMP4 BMP4 NOG NOG KLF10 KLF10 PPARGC1B PPARGC1B MEF2D MEF2D SEMA4D SEMA4D RUNX1 RUNX1 ENSGAGP00000018246 ENSGAGP00000018246 ZBTB16 ZBTB16 ANKH ANKH SLC26A2 SLC26A2 MN1 MN1 EXT2 EXT2 CTNNB1 CTNNB1 ASF1A ASF1A TNN TNN BMP6 BMP6 ENSGAGP00000022008 ENSGAGP00000022008 UCMA UCMA TWSG1 TWSG1 PAM16 PAM16 ENSGAGP00000023312 ENSGAGP00000023312 MMP13 MMP13 MYF5 MYF5 PTHLH PTHLH SHH SHH JUND JUND BCL2 BCL2 TBC1D31 TBC1D31 IBSP IBSP ENSGAGP00000024986 ENSGAGP00000024986 BMPR1A BMPR1A IGF2 IGF2 PDLIM7 PDLIM7 TGFB1 TGFB1 CCN1 CCN1 ENSGAGP00000026454 ENSGAGP00000026454 ENSGAGP00000026458 ENSGAGP00000026458 GDF10 GDF10 BMP3 BMP3 ENSGAGP00000027216 ENSGAGP00000027216 ENSGAGP00000027874 ENSGAGP00000027874 GLI3 GLI3 FBXL15 FBXL15 EPHA2 EPHA2 SP3 SP3 CCN2 CCN2 WWOX WWOX PHOSPHO1 PHOSPHO1 ENSGAGP00000030020 ENSGAGP00000030020 MEN1 MEN1 ENSGAGP00000030884 ENSGAGP00000030884 SORT1 SORT1 SNAI1 SNAI1 SUCO SUCO EIF2AK3 EIF2AK3 ZMPSTE24 ZMPSTE24 NF1 NF1 GLIS1 GLIS1 SMAD1 SMAD1 TNFRSF11A TNFRSF11A MYOC MYOC KAZALD1 KAZALD1 BMPR2 BMPR2 PTN PTN CLEC3A CLEC3A ENSGAGP00000034060 ENSGAGP00000034060 ENSGAGP00000034063 ENSGAGP00000034063 SOST SOST PTH PTH RUNX2 RUNX2 ADAMTS7 ADAMTS7 IFT80 IFT80 CTHRC1 CTHRC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MGPMatrix Gla protein; Associates with the organic matrix of bone and cartilage. (92 aa)
DHX36DEAH-box helicase 36. (936 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
CALCRCalcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (455 aa)
ENSGAGP00000000858Uncharacterized protein. (130 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1285 aa)
JUNBJunB proto-oncogene, AP-1 transcription factor subunit. (319 aa)
ECM1Extracellular matrix protein 1. (450 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
TP53INP2Tumor protein p53 inducible nuclear protein 2. (239 aa)
SOX8SRY-box transcription factor 8. (461 aa)
NAB2NGFI-A binding protein 2. (469 aa)
CLEC3BC-type lectin domain family 3 member B. (201 aa)
BMP2Bone morphogenetic protein 2. (392 aa)
ENSGAGP00000005402Uncharacterized protein. (439 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (810 aa)
ENSGAGP00000006046HH_signal domain-containing protein. (197 aa)
IHHIndian hedgehog signaling molecule. (224 aa)
FGF18Fibroblast growth factor 18; Belongs to the heparin-binding growth factors family. (153 aa)
MMP9Matrix metallopeptidase 9. (710 aa)
GATA1GATA binding protein 1. (359 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
FSTL3Follistatin like 3. (252 aa)
ENSGAGP00000006994Uncharacterized protein. (110 aa)
MSX2Msh homeobox 2. (126 aa)
ENSGAGP00000007080MATH domain-containing protein. (140 aa)
AHSGAlpha 2-HS glycoprotein. (327 aa)
ENSGAGP00000008310Uncharacterized protein. (155 aa)
ENSGAGP00000008368PIP49_C domain-containing protein. (300 aa)
IMPAD1Inositol monophosphatase domain containing 1. (356 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (482 aa)
ENSGAGP00000008932Pep_M12B_propep domain-containing protein. (211 aa)
CBFBUncharacterized protein. (71 aa)
LGR4Leucine rich repeat containing G protein-coupled receptor 4. (952 aa)
HAND2Heart and neural crest derivatives expressed 2. (212 aa)
ENSGAGP00000009577RING-type domain-containing protein. (38 aa)
MMP14Matrix metallopeptidase 14. (510 aa)
PHOSPHO2Phosphatase, orphan 2. (270 aa)
PEX7Peroxisomal biogenesis factor 7. (306 aa)
ENSGAGP00000010858TGF_BETA_2 domain-containing protein. (426 aa)
MAPK11Mitogen-activated protein kinase. (361 aa)
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (321 aa)
NPPCNatriuretic peptide C. (115 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
IGFBP5Insulin like growth factor binding protein 5. (276 aa)
TMEM38BTransmembrane protein 38B. (255 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa)
ENSGAGP00000012687EXPERA domain-containing protein. (231 aa)
DLX5Distal-less homeobox 5. (335 aa)
ADARAdenosine deaminase RNA specific. (1175 aa)
ENSGAGP00000013084Noggin; Belongs to the noggin family. (212 aa)
DHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (414 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (805 aa)
ENSGAGP00000013860Endo/exonuclease/phosphatase domain-containing protein. (480 aa)
RUNX3Runt-related transcription factor. (379 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
THBS3Thrombospondin 3. (918 aa)
TMEM119Transmembrane protein 119. (248 aa)
ENSGAGP00000015098Uncharacterized protein; Belongs to the heparin-binding growth factors family. (171 aa)
PKDCCProtein kinase domain containing, cytoplasmic. (512 aa)
TGFB3Transforming growth factor beta 3. (456 aa)
ATF4Activating transcription factor 4. (354 aa)
MESDMesoderm development LRP chaperone. (222 aa)
BMP4Bone morphogenetic protein 4. (403 aa)
NOGNoggin; Belongs to the noggin family. (223 aa)
KLF10Kruppel like factor 10. (438 aa)
PPARGC1BPPARG coactivator 1 beta. (1026 aa)
MEF2DMyocyte enhancer factor 2D. (512 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (860 aa)
RUNX1Runt-related transcription factor. (473 aa)
ENSGAGP00000018246SH2 domain-containing protein. (836 aa)
ZBTB16Zinc finger and BTB domain containing 16. (665 aa)
ANKHANKH inorganic pyrophosphate transport regulator. (446 aa)
SLC26A2Sulfate transporter; Sulfate transporter. May play a role in endochondral bone formation; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (707 aa)
MN1MN1 proto-oncogene, transcriptional regulator. (1059 aa)
EXT2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (718 aa)
CTNNB1Catenin beta 1. (781 aa)
ASF1AAnti-silencing function 1A histone chaperone. (204 aa)
TNNTenascin N. (959 aa)
BMP6Bone morphogenetic protein 6. (477 aa)
ENSGAGP00000022008Osteocalcin; Binds strongly to apatite and calcium. (93 aa)
UCMAUpper zone of growth plate and cartilage matrix associated. (102 aa)
TWSG1Twisted gastrulation BMP signaling modulator 1. (223 aa)
PAM16Presequence translocase associated motor 16. (127 aa)
ENSGAGP00000023312ZnMc domain-containing protein. (341 aa)
MMP13Matrix metallopeptidase 13. (387 aa)
MYF5Myogenic factor. (254 aa)
PTHLHParathyroid hormone like hormone. (177 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (426 aa)
JUNDJunD proto-oncogene, AP-1 transcription factor subunit. (289 aa)
BCL2BCL2 apoptosis regulator. (220 aa)
TBC1D31TBC1 domain family member 31. (1087 aa)
IBSPIntegrin binding sialoprotein. (307 aa)
ENSGAGP00000024986Uncharacterized protein. (316 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (521 aa)
IGF2Insulin like growth factor 2. (186 aa)
PDLIM7PDZ and LIM domain 7. (462 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (387 aa)
CCN1Cellular communication network factor 1. (375 aa)
ENSGAGP00000026454C-type lectin domain-containing protein. (198 aa)
ENSGAGP00000026458C-type lectin domain-containing protein. (169 aa)
GDF10Bone morphogenetic protein 3; Belongs to the TGF-beta family. (457 aa)
BMP3Bone morphogenetic protein 3; Belongs to the TGF-beta family. (475 aa)
ENSGAGP00000027216Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1609 aa)
ENSGAGP00000027874Uncharacterized protein. (136 aa)
GLI3GLI family zinc finger 3. (1575 aa)
FBXL15F-box and leucine rich repeat protein 15. (295 aa)
EPHA2EPH receptor A2. (976 aa)
SP3Sp3 transcription factor. (770 aa)
CCN2Cellular communication network factor 2. (485 aa)
WWOXWW domain containing oxidoreductase. (200 aa)
PHOSPHO1Phosphoethanolamine/phosphocholine phosphatase. (268 aa)
ENSGAGP00000030020Uncharacterized protein. (719 aa)
MEN1Menin 1. (501 aa)
ENSGAGP00000030884Uncharacterized protein; Belongs to the semaphorin family. (784 aa)
SORT1Sortilin. (838 aa)
SNAI1Snail family transcriptional repressor 1. (250 aa)
SUCOSUN domain containing ossification factor. (1160 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1010 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (467 aa)
NF1Neurofibromin 1. (2838 aa)
GLIS1GLIS family zinc finger 1. (766 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
TNFRSF11ATNF receptor superfamily member 11a. (672 aa)
MYOCMyocilin. (501 aa)
KAZALD1Kazal type serine peptidase inhibitor domain 1. (300 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1042 aa)
PTNPleiotrophin. (230 aa)
CLEC3AC-type lectin domain family 3 member A. (196 aa)
ENSGAGP00000034060Uncharacterized protein. (140 aa)
ENSGAGP00000034063Uncharacterized protein. (60 aa)
SOSTSclerostin. (213 aa)
PTHParathyroid hormone. (124 aa)
RUNX2Runt-related transcription factor. (456 aa)
ADAMTS7ADAM metallopeptidase with thrombospondin type 1 motif 7. (1548 aa)
IFT80Intraflagellar transport 80. (786 aa)
CTHRC1Collagen triple helix repeat containing 1. (240 aa)
Your Current Organism:
Gopherus agassizii
NCBI taxonomy Id: 38772
Other names: G. agassizii, Gopherus agassizi, Gopherus polyphemus agassizii, USNM 7888, desert tortoise
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