(25 nodes) ATPase, AAA-type, conserved site network (Gopherus agassizii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSGAGP00000012781	Uncharacterized protein; Belongs to the AAA ATPase family. (437 aa)
	ATAD2	ATPase family AAA domain containing 2. (1369 aa)
	SPAST	Spastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Required for membrane traffic from the endoplasmic reticulum (ER) to the Go [...] (616 aa)
	PEX1	Peroxisomal biogenesis factor 1. (1334 aa)
	PSMC2	Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
	PEX6	Peroxisomal biogenesis factor 6. (715 aa)
	TRIP13	Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family. (436 aa)
	PSMC3	Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (422 aa)
	KATNA1	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. (495 aa)
	NSF	N-ethylmaleimide sensitive factor, vesicle fusing ATPase. (742 aa)
	SPATA5	Spermatogenesis associated 5. (879 aa)
	VCP	Valosin containing protein; Belongs to the AAA ATPase family. (761 aa)
	PSMC6	Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa)
	NVL	Nuclear VCP like. (858 aa)
	ATAD1	ATPase family AAA domain containing 1; Belongs to the AAA ATPase family. (361 aa)
	ENSGAGP00000015915	Uncharacterized protein; Belongs to the AAA ATPase family. (766 aa)
	PSMC1	Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
	KATNAL1	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. (413 aa)
	FIGNL1	Fidgetin like 1; Belongs to the AAA ATPase family. (689 aa)
	ENSGAGP00000009506	AAA domain-containing protein; Belongs to the AAA ATPase family. (620 aa)
	YME1L1	YME1 like 1 ATPase. (715 aa)
	PSMC5	Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (460 aa)
	BCS1L	BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone; Belongs to the AAA ATPase family. (419 aa)
	ATAD2B	ATPase family AAA domain containing 2B. (1436 aa)
	SPATA5L1	Spermatogenesis associated 5 like 1. (715 aa)

Your Current Organism:

Gopherus agassizii

NCBI taxonomy Id: 38772
Other names: G. agassizii, Gopherus agassizi, Gopherus polyphemus agassizii, USNM 7888, desert tortoise

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATAD1	ATAD2	ENSGAGP00000030599	ENSGAGP00000017959	ATPase family AAA domain containing 1; Belongs to the AAA ATPase family.	ATPase family AAA domain containing 2.	0.473
ATAD1	ATAD2B	ENSGAGP00000030599	ENSGAGP00000028416	ATPase family AAA domain containing 1; Belongs to the AAA ATPase family.	ATPase family AAA domain containing 2B.	0.473
ATAD1	ENSGAGP00000012781	ENSGAGP00000030599	ENSGAGP00000012781	ATPase family AAA domain containing 1; Belongs to the AAA ATPase family.	Uncharacterized protein; Belongs to the AAA ATPase family.	0.432
ATAD1	KATNA1	ENSGAGP00000030599	ENSGAGP00000007390	ATPase family AAA domain containing 1; Belongs to the AAA ATPase family.	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.	0.496
ATAD1	KATNAL1	ENSGAGP00000030599	ENSGAGP00000000541	ATPase family AAA domain containing 1; Belongs to the AAA ATPase family.	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.	0.501
ATAD1	PSMC1	ENSGAGP00000030599	ENSGAGP00000003960	ATPase family AAA domain containing 1; Belongs to the AAA ATPase family.	Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family.	0.509
ATAD1	PSMC2	ENSGAGP00000030599	ENSGAGP00000017539	ATPase family AAA domain containing 1; Belongs to the AAA ATPase family.	Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family.	0.503
ATAD1	PSMC3	ENSGAGP00000030599	ENSGAGP00000007417	ATPase family AAA domain containing 1; Belongs to the AAA ATPase family.	Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family.	0.554
ATAD1	PSMC5	ENSGAGP00000030599	ENSGAGP00000013012	ATPase family AAA domain containing 1; Belongs to the AAA ATPase family.	Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family.	0.516
ATAD1	PSMC6	ENSGAGP00000030599	ENSGAGP00000004914	ATPase family AAA domain containing 1; Belongs to the AAA ATPase family.	Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family.	0.619
ATAD2	ATAD1	ENSGAGP00000017959	ENSGAGP00000030599	ATPase family AAA domain containing 2.	ATPase family AAA domain containing 1; Belongs to the AAA ATPase family.	0.473
ATAD2	ENSGAGP00000012781	ENSGAGP00000017959	ENSGAGP00000012781	ATPase family AAA domain containing 2.	Uncharacterized protein; Belongs to the AAA ATPase family.	0.421
ATAD2	ENSGAGP00000015915	ENSGAGP00000017959	ENSGAGP00000015915	ATPase family AAA domain containing 2.	Uncharacterized protein; Belongs to the AAA ATPase family.	0.628
ATAD2	FIGNL1	ENSGAGP00000017959	ENSGAGP00000015466	ATPase family AAA domain containing 2.	Fidgetin like 1; Belongs to the AAA ATPase family.	0.473
ATAD2	NSF	ENSGAGP00000017959	ENSGAGP00000005428	ATPase family AAA domain containing 2.	N-ethylmaleimide sensitive factor, vesicle fusing ATPase.	0.473
ATAD2	NVL	ENSGAGP00000017959	ENSGAGP00000022913	ATPase family AAA domain containing 2.	Nuclear VCP like.	0.500
ATAD2	PEX1	ENSGAGP00000017959	ENSGAGP00000020458	ATPase family AAA domain containing 2.	Peroxisomal biogenesis factor 1.	0.473
ATAD2	PEX6	ENSGAGP00000017959	ENSGAGP00000036248	ATPase family AAA domain containing 2.	Peroxisomal biogenesis factor 6.	0.473
ATAD2	PSMC3	ENSGAGP00000017959	ENSGAGP00000007417	ATPase family AAA domain containing 2.	Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family.	0.814
ATAD2	PSMC6	ENSGAGP00000017959	ENSGAGP00000004914	ATPase family AAA domain containing 2.	Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family.	0.814