(12 nodes) Alcohol dehydrogenase-like, C-terminal network (Gopherus agassizii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ADH5	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (374 aa)
	PTGR1	Prostaglandin reductase 1. (361 aa)
	ENSGAGP00000001002	PKS_ER domain-containing protein. (358 aa)
	SORD	Sorbitol dehydrogenase. (356 aa)
	CRYZ	Crystallin zeta. (329 aa)
	ENSGAGP00000007079	Uncharacterized protein. (344 aa)
	ENSGAGP00000008030	PKS_ER domain-containing protein. (376 aa)
	ENSGAGP00000009317	Uncharacterized protein. (296 aa)
	FASN	Fatty acid synthase. (2513 aa)
	MECR	Mitochondrial trans-2-enoyl-CoA reductase. (329 aa)
	ZADH2	Zinc binding alcohol dehydrogenase domain containing 2. (408 aa)
	TP53I3	Tumor protein p53 inducible protein 3. (314 aa)

Your Current Organism:

Gopherus agassizii

NCBI taxonomy Id: 38772
Other names: G. agassizii, Gopherus agassizi, Gopherus polyphemus agassizii, USNM 7888, desert tortoise

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADH5	CRYZ	ENSGAGP00000007067	ENSGAGP00000004205	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.	Crystallin zeta.	0.452
ADH5	ENSGAGP00000001002	ENSGAGP00000007067	ENSGAGP00000001002	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.	PKS_ER domain-containing protein.	0.486
ADH5	ENSGAGP00000008030	ENSGAGP00000007067	ENSGAGP00000008030	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.	PKS_ER domain-containing protein.	0.557
ADH5	MECR	ENSGAGP00000007067	ENSGAGP00000016522	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.	Mitochondrial trans-2-enoyl-CoA reductase.	0.460
ADH5	SORD	ENSGAGP00000007067	ENSGAGP00000003278	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.	Sorbitol dehydrogenase.	0.602
ADH5	TP53I3	ENSGAGP00000007067	ENSGAGP00000032473	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.	Tumor protein p53 inducible protein 3.	0.452
ADH5	ZADH2	ENSGAGP00000007067	ENSGAGP00000021362	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.	Zinc binding alcohol dehydrogenase domain containing 2.	0.452
CRYZ	ADH5	ENSGAGP00000004205	ENSGAGP00000007067	Crystallin zeta.	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.	0.452
CRYZ	ENSGAGP00000007079	ENSGAGP00000004205	ENSGAGP00000007079	Crystallin zeta.	Uncharacterized protein.	0.452
CRYZ	ENSGAGP00000008030	ENSGAGP00000004205	ENSGAGP00000008030	Crystallin zeta.	PKS_ER domain-containing protein.	0.452
CRYZ	FASN	ENSGAGP00000004205	ENSGAGP00000016001	Crystallin zeta.	Fatty acid synthase.	0.745
CRYZ	SORD	ENSGAGP00000004205	ENSGAGP00000003278	Crystallin zeta.	Sorbitol dehydrogenase.	0.594
ENSGAGP00000001002	ADH5	ENSGAGP00000001002	ENSGAGP00000007067	PKS_ER domain-containing protein.	S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.	0.486
ENSGAGP00000001002	ENSGAGP00000007079	ENSGAGP00000001002	ENSGAGP00000007079	PKS_ER domain-containing protein.	Uncharacterized protein.	0.486
ENSGAGP00000001002	ENSGAGP00000008030	ENSGAGP00000001002	ENSGAGP00000008030	PKS_ER domain-containing protein.	PKS_ER domain-containing protein.	0.486
ENSGAGP00000001002	FASN	ENSGAGP00000001002	ENSGAGP00000016001	PKS_ER domain-containing protein.	Fatty acid synthase.	0.745
ENSGAGP00000001002	SORD	ENSGAGP00000001002	ENSGAGP00000003278	PKS_ER domain-containing protein.	Sorbitol dehydrogenase.	0.567
ENSGAGP00000007079	CRYZ	ENSGAGP00000007079	ENSGAGP00000004205	Uncharacterized protein.	Crystallin zeta.	0.452
ENSGAGP00000007079	ENSGAGP00000001002	ENSGAGP00000007079	ENSGAGP00000001002	Uncharacterized protein.	PKS_ER domain-containing protein.	0.486
ENSGAGP00000007079	MECR	ENSGAGP00000007079	ENSGAGP00000016522	Uncharacterized protein.	Mitochondrial trans-2-enoyl-CoA reductase.	0.460