node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGMO | FA2H | ENSGAGP00000031769 | ENSGAGP00000002743 | Alkylglycerol monooxygenase; Belongs to the sterol desaturase family. | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] | 0.567 |
CH25H | FA2H | ENSGAGP00000029107 | ENSGAGP00000002743 | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] | 0.863 |
CH25H | SC5D | ENSGAGP00000029107 | ENSGAGP00000002650 | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. | Sterol-C5-desaturase; Belongs to the sterol desaturase family. | 0.997 |
FA2H | AGMO | ENSGAGP00000002743 | ENSGAGP00000031769 | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] | Alkylglycerol monooxygenase; Belongs to the sterol desaturase family. | 0.567 |
FA2H | CH25H | ENSGAGP00000002743 | ENSGAGP00000029107 | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. | 0.863 |
FA2H | FAXDC2 | ENSGAGP00000002743 | ENSGAGP00000035312 | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] | Fatty acid hydroxylase domain containing 2; Belongs to the sterol desaturase family. | 0.863 |
FA2H | MSMO1 | ENSGAGP00000002743 | ENSGAGP00000026982 | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] | Methylsterol monooxygenase 1; Belongs to the sterol desaturase family. | 0.863 |
FA2H | SC5D | ENSGAGP00000002743 | ENSGAGP00000002650 | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] | Sterol-C5-desaturase; Belongs to the sterol desaturase family. | 0.778 |
FAXDC2 | FA2H | ENSGAGP00000035312 | ENSGAGP00000002743 | Fatty acid hydroxylase domain containing 2; Belongs to the sterol desaturase family. | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] | 0.863 |
FAXDC2 | SC5D | ENSGAGP00000035312 | ENSGAGP00000002650 | Fatty acid hydroxylase domain containing 2; Belongs to the sterol desaturase family. | Sterol-C5-desaturase; Belongs to the sterol desaturase family. | 0.997 |
MSMO1 | FA2H | ENSGAGP00000026982 | ENSGAGP00000002743 | Methylsterol monooxygenase 1; Belongs to the sterol desaturase family. | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] | 0.863 |
MSMO1 | SC5D | ENSGAGP00000026982 | ENSGAGP00000002650 | Methylsterol monooxygenase 1; Belongs to the sterol desaturase family. | Sterol-C5-desaturase; Belongs to the sterol desaturase family. | 0.997 |
SC5D | CH25H | ENSGAGP00000002650 | ENSGAGP00000029107 | Sterol-C5-desaturase; Belongs to the sterol desaturase family. | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. | 0.997 |
SC5D | FA2H | ENSGAGP00000002650 | ENSGAGP00000002743 | Sterol-C5-desaturase; Belongs to the sterol desaturase family. | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] | 0.778 |
SC5D | FAXDC2 | ENSGAGP00000002650 | ENSGAGP00000035312 | Sterol-C5-desaturase; Belongs to the sterol desaturase family. | Fatty acid hydroxylase domain containing 2; Belongs to the sterol desaturase family. | 0.997 |
SC5D | MSMO1 | ENSGAGP00000002650 | ENSGAGP00000026982 | Sterol-C5-desaturase; Belongs to the sterol desaturase family. | Methylsterol monooxygenase 1; Belongs to the sterol desaturase family. | 0.997 |