STRINGSTRING
ORC1 ORC1 IGHMBP2 IGHMBP2 ABCG8 ABCG8 ABCG5 ABCG5 BCS1L BCS1L ABCD3 ABCD3 RFC4 RFC4 HELZ2 HELZ2 ENSGAGP00000026498 ENSGAGP00000026498 SNRNP200 SNRNP200 RFC3 RFC3 ABCF1 ABCF1 ABCC8 ABCC8 ENSGAGP00000025054 ENSGAGP00000025054 ENSGAGP00000025043 ENSGAGP00000025043 DNAH5 DNAH5 PIF1 PIF1 FIGNL2 FIGNL2 DYNC2H1 DYNC2H1 ENSGAGP00000023132 ENSGAGP00000023132 NVL NVL LONP1 LONP1 GPN1 GPN1 ABCA4 ABCA4 SPG7 SPG7 ABCC1 ABCC1 ABCC6 ABCC6 MCM9 MCM9 DNAH10 DNAH10 MCM3 MCM3 PEX1 PEX1 DYNC1H1 DYNC1H1 FIGN FIGN PEX6 PEX6 ABCA5 ABCA5 ENSGAGP00000035589 ENSGAGP00000035589 ABCA10 ABCA10 CFTR CFTR RAD17 RAD17 ABCB5 ABCB5 IQCA1 IQCA1 RFC2 RFC2 SPAST SPAST NAV3 NAV3 ABCB9 ABCB9 SPATA5L1 SPATA5L1 MMAA MMAA ATAD3A ATAD3A ORC4 ORC4 TRIP13 TRIP13 TOR2A TOR2A ENSGAGP00000031720 ENSGAGP00000031720 ABCG4 ABCG4 NTPCR NTPCR DNAH1 DNAH1 WRNIP1 WRNIP1 RNF213 RNF213 ATAD1 ATAD1 KATNAL2 KATNAL2 RAD51B RAD51B NAV1 NAV1 ABCC9 ABCC9 ASCC3 ASCC3 MDN1 MDN1 ATAD2B ATAD2B DHX16 DHX16 PSMC1 PSMC1 RAD51D RAD51D DHX37 DHX37 ABCA1 ABCA1 PSMC6 PSMC6 ENSGAGP00000005019 ENSGAGP00000005019 NSF NSF DNAH6 DNAH6 ATAD5 ATAD5 ABCE1 ABCE1 ABCC5 ABCC5 ENSGAGP00000007263 ENSGAGP00000007263 KATNA1 KATNA1 PSMC3 PSMC3 DNAH3 DNAH3 ENSGAGP00000007812 ENSGAGP00000007812 ABCA3 ABCA3 CDC6 CDC6 ABCB8 ABCB8 ENSGAGP00000009506 ENSGAGP00000009506 KATNAL1 KATNAL1 LONP2 LONP2 ATP5F1B ATP5F1B CLPB CLPB ENSGAGP00000001795 ENSGAGP00000001795 RUVBL1 RUVBL1 ABCB11 ABCB11 ENSGAGP00000019709 ENSGAGP00000019709 ABCB7 ABCB7 ENSGAGP00000018281 ENSGAGP00000018281 NAV2 NAV2 ATAD2 ATAD2 ABCB6 ABCB6 RAD51 RAD51 PSMC2 PSMC2 ABCD2 ABCD2 ABCD4 ABCD4 ENSGAGP00000016013 ENSGAGP00000016013 ENSGAGP00000015915 ENSGAGP00000015915 FIGNL1 FIGNL1 ENSGAGP00000015394 ENSGAGP00000015394 VCP VCP SPATA5 SPATA5 ABCG1 ABCG1 ENSGAGP00000014058 ENSGAGP00000014058 ENSGAGP00000013458 ENSGAGP00000013458 YME1L1 YME1L1 ABCA2 ABCA2 PSMC5 PSMC5 ENSGAGP00000012781 ENSGAGP00000012781 ABCB10 ABCB10 CLPX CLPX ABCC4 ABCC4 ENSGAGP00000010898 ENSGAGP00000010898 TAP1 TAP1 ENSGAGP00000010492 ENSGAGP00000010492 MCM7 MCM7 RFC5 RFC5 ENSGAGP00000009746 ENSGAGP00000009746 CHTF18 CHTF18
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ORC1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (894 aa)
IGHMBP2Immunoglobulin mu DNA binding protein 2. (1075 aa)
ABCG8ATP binding cassette subfamily G member 8. (660 aa)
ABCG5ATP binding cassette subfamily G member 5. (654 aa)
BCS1LBCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone; Belongs to the AAA ATPase family. (419 aa)
ABCD3ATP binding cassette subfamily D member 3. (666 aa)
RFC4Replication factor C subunit 4. (364 aa)
HELZ2Helicase with zinc finger 2. (2826 aa)
ENSGAGP00000026498Uncharacterized protein. (2239 aa)
SNRNP200Small nuclear ribonucleoprotein U5 subunit 200. (2056 aa)
RFC3Replication factor C subunit 3. (295 aa)
ABCF1ATP binding cassette subfamily F member 1. (919 aa)
ABCC8ATP binding cassette subfamily C member 8. (1612 aa)
ENSGAGP00000025054ABC transporter domain-containing protein. (658 aa)
ENSGAGP00000025043ABC transporter domain-containing protein. (655 aa)
DNAH5Dynein axonemal heavy chain 5. (4634 aa)
PIF1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (649 aa)
FIGNL2Fidgetin like 2; Belongs to the AAA ATPase family. (720 aa)
DYNC2H1Dynein cytoplasmic 2 heavy chain 1. (4123 aa)
ENSGAGP00000023132ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (524 aa)
NVLNuclear VCP like. (858 aa)
LONP1Lon protease homolog; Belongs to the peptidase S16 family. (897 aa)
GPN1GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import. (376 aa)
ABCA4ATP binding cassette subfamily A member 4. (2274 aa)
SPG7SPG7 matrix AAA peptidase subunit, paraplegin. (543 aa)
ABCC1ATP binding cassette subfamily C member 1. (1533 aa)
ABCC6ATP binding cassette subfamily C member 6. (1508 aa)
MCM9Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1177 aa)
DNAH10Dynein axonemal heavy chain 10. (4498 aa)
MCM3DNA helicase; Belongs to the MCM family. (812 aa)
PEX1Peroxisomal biogenesis factor 1. (1334 aa)
DYNC1H1Dynein cytoplasmic 1 heavy chain 1. (4549 aa)
FIGNFidgetin, microtubule severing factor; Belongs to the AAA ATPase family. (748 aa)
PEX6Peroxisomal biogenesis factor 6. (715 aa)
ABCA5ATP binding cassette subfamily A member 5. (1646 aa)
ENSGAGP00000035589Uncharacterized protein. (1446 aa)
ABCA10ATP binding cassette subfamily A member 10. (1641 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1405 aa)
RAD17RAD17 checkpoint clamp loader component. (691 aa)
ABCB5ATP binding cassette subfamily B member 5. (1270 aa)
IQCA1IQ motif containing with AAA domain 1. (797 aa)
RFC2Replication factor C subunit 2. (353 aa)
SPASTSpastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Required for membrane traffic from the endoplasmic reticulum (ER) to the Go [...] (616 aa)
NAV3Neuron navigator 3. (2206 aa)
ABCB9ATP binding cassette subfamily B member 9. (787 aa)
SPATA5L1Spermatogenesis associated 5 like 1. (715 aa)
MMAAMetabolism of cobalamin associated A. (414 aa)
ATAD3AATPase family AAA domain containing 3A. (602 aa)
ORC4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (425 aa)
TRIP13Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family. (436 aa)
TOR2ATorsin. (316 aa)
ENSGAGP00000031720Uncharacterized protein. (593 aa)
ABCG4ATP binding cassette subfamily G member 4. (657 aa)
NTPCRNucleoside-triphosphatase, cancer-related. (190 aa)
DNAH1Dynein axonemal heavy chain 1. (4233 aa)
WRNIP1WRN helicase interacting protein 1. (510 aa)
RNF213Ring finger protein 213. (4842 aa)
ATAD1ATPase family AAA domain containing 1; Belongs to the AAA ATPase family. (361 aa)
KATNAL2Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. (368 aa)
RAD51BRAD51 paralog B. (359 aa)
NAV1Neuron navigator 1. (1372 aa)
ABCC9ATP binding cassette subfamily C member 9. (1560 aa)
ASCC3Activating signal cointegrator 1 complex subunit 3. (1983 aa)
MDN1Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family. (5532 aa)
ATAD2BATPase family AAA domain containing 2B. (1436 aa)
DHX16DEAH-box helicase 16. (957 aa)
PSMC1Proteasome 26S subunit, ATPase 1; Belongs to the AAA ATPase family. (440 aa)
RAD51DDNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents; Belongs to the RecA family. RAD51 subfamily. (329 aa)
DHX37DEAH-box helicase 37. (1145 aa)
ABCA1ATP binding cassette subfamily A member 1. (2270 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa)
ENSGAGP00000005019Uncharacterized protein. (3004 aa)
NSFN-ethylmaleimide sensitive factor, vesicle fusing ATPase. (742 aa)
DNAH6Dynein axonemal heavy chain 6. (4113 aa)
ATAD5ATPase family AAA domain containing 5. (1842 aa)
ABCE1ATP binding cassette subfamily E member 1. (449 aa)
ABCC5ATP binding cassette subfamily C member 5. (1410 aa)
ENSGAGP00000007263Uncharacterized protein. (1308 aa)
KATNA1Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. (495 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (422 aa)
DNAH3Dynein axonemal heavy chain 3. (3978 aa)
ENSGAGP00000007812Uncharacterized protein. (1493 aa)
ABCA3ATP binding cassette subfamily A member 3. (1707 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (557 aa)
ABCB8ATP binding cassette subfamily B member 8. (619 aa)
ENSGAGP00000009506AAA domain-containing protein; Belongs to the AAA ATPase family. (620 aa)
KATNAL1Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. (413 aa)
LONP2Lon N-terminal domain-containing protein. (682 aa)
ATP5F1BATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (433 aa)
CLPBClpB homolog, mitochondrial AAA ATPase chaperonin. (665 aa)
ENSGAGP00000001795Uncharacterized protein. (1543 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
ABCB11ATP binding cassette subfamily B member 11. (1294 aa)
ENSGAGP00000019709ABC transporter domain-containing protein. (659 aa)
ABCB7ATP binding cassette subfamily B member 7. (683 aa)
ENSGAGP00000018281Uncharacterized protein. (1198 aa)
NAV2Neuron navigator 2. (2430 aa)
ATAD2ATPase family AAA domain containing 2. (1369 aa)
ABCB6ATP binding cassette subfamily B member 6 (Langereis blood group). (385 aa)
RAD51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (365 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
ABCD2ATP binding cassette subfamily D member 2. (756 aa)
ABCD4ATP binding cassette subfamily D member 4. (602 aa)
ENSGAGP00000016013Uncharacterized protein. (623 aa)
ENSGAGP00000015915Uncharacterized protein; Belongs to the AAA ATPase family. (766 aa)
FIGNL1Fidgetin like 1; Belongs to the AAA ATPase family. (689 aa)
ENSGAGP00000015394Uncharacterized protein. (1247 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (761 aa)
SPATA5Spermatogenesis associated 5. (879 aa)
ABCG1ATP binding cassette subfamily G member 1. (637 aa)
ENSGAGP00000014058Uncharacterized protein. (1302 aa)
ENSGAGP00000013458Uncharacterized protein. (3966 aa)
YME1L1YME1 like 1 ATPase. (715 aa)
ABCA2ATP binding cassette subfamily A member 2. (2438 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (460 aa)
ENSGAGP00000012781Uncharacterized protein; Belongs to the AAA ATPase family. (437 aa)
ABCB10ATP binding cassette subfamily B member 10. (604 aa)
CLPXCaseinolytic mitochondrial matrix peptidase chaperone subunit. (630 aa)
ABCC4ATP binding cassette subfamily C member 4. (1331 aa)
ENSGAGP00000010898MCM domain-containing protein; Belongs to the MCM family. (825 aa)
TAP1Transporter 1, ATP binding cassette subfamily B member. (721 aa)
ENSGAGP00000010492Uncharacterized protein. (712 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (577 aa)
RFC5Replication factor C subunit 5. (338 aa)
ENSGAGP00000009746ABC transporter domain-containing protein. (335 aa)
CHTF18Chromosome transmission fidelity factor 18. (836 aa)
Your Current Organism:
Gopherus agassizii
NCBI taxonomy Id: 38772
Other names: G. agassizii, Gopherus agassizi, Gopherus polyphemus agassizii, USNM 7888, desert tortoise
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