STRINGSTRING
LY96 LY96 ENSGAGP00000036468 ENSGAGP00000036468 ENSGAGP00000036322 ENSGAGP00000036322 MAP2K6 MAP2K6 PIK3R1 PIK3R1 CASP8 CASP8 TAB2 TAB2 ENSGAGP00000033759 ENSGAGP00000033759 MAPK8 MAPK8 ENSGAGP00000009221 ENSGAGP00000009221 TBK1 TBK1 MAP2K4 MAP2K4 JUN JUN ENSGAGP00000031386 ENSGAGP00000031386 AKT2 AKT2 ENSGAGP00000029623 ENSGAGP00000029623 MAP3K7 MAP3K7 MAP2K7 MAP2K7 AKT3 AKT3 ENSGAGP00000028746 ENSGAGP00000028746 MAPK1 MAPK1 ENSGAGP00000028590 ENSGAGP00000028590 FADD FADD ENSGAGP00000026930 ENSGAGP00000026930 ENSGAGP00000026688 ENSGAGP00000026688 ENSGAGP00000026680 ENSGAGP00000026680 ENSGAGP00000026676 ENSGAGP00000026676 TLR7 TLR7 CHUK CHUK CXCL8 CXCL8 ENSGAGP00000025784 ENSGAGP00000025784 ENSGAGP00000025430 ENSGAGP00000025430 ENSGAGP00000025426 ENSGAGP00000025426 IFNAR1 IFNAR1 ENSGAGP00000025067 ENSGAGP00000025067 ENSGAGP00000024986 ENSGAGP00000024986 TLR3 TLR3 ENSGAGP00000022225 ENSGAGP00000022225 IRAK4 IRAK4 TAB1 TAB1 ENSGAGP00000021019 ENSGAGP00000021019 IRF7 IRF7 ENSGAGP00000017572 ENSGAGP00000017572 ENSGAGP00000016699 ENSGAGP00000016699 PIK3CD PIK3CD MAPK9 MAPK9 ENSGAGP00000016239 ENSGAGP00000016239 ENSGAGP00000016238 ENSGAGP00000016238 ENSGAGP00000016236 ENSGAGP00000016236 CCL16 CCL16 ENSGAGP00000015634 ENSGAGP00000015634 CCL5 CCL5 ENSGAGP00000015630 ENSGAGP00000015630 ENSGAGP00000015040 ENSGAGP00000015040 ENSGAGP00000014753 ENSGAGP00000014753 ENSGAGP00000014676 ENSGAGP00000014676 ENSGAGP00000014455 ENSGAGP00000014455 ENSGAGP00000014454 ENSGAGP00000014454 IL6 IL6 RIPK1 RIPK1 IRF5 IRF5 ENSGAGP00000008157 ENSGAGP00000008157 TMED3 TMED3 ENSGAGP00000007913 ENSGAGP00000007913 TLR4 TLR4 TIRAP TIRAP MAPK13 MAPK13 TNF TNF ENSGAGP00000007080 ENSGAGP00000007080 ENSGAGP00000006929 ENSGAGP00000006929 ENSGAGP00000006608 ENSGAGP00000006608 ENSGAGP00000006339 ENSGAGP00000006339 ENSGAGP00000006113 ENSGAGP00000006113 MAPK10 MAPK10 MAP2K1 MAP2K1 ENSGAGP00000004868 ENSGAGP00000004868 IRF6 IRF6 ENSGAGP00000003436 ENSGAGP00000003436 ENSGAGP00000003429 ENSGAGP00000003429 ENSGAGP00000002241 ENSGAGP00000002241 MAPK3 MAPK3 ENSGAGP00000001654 ENSGAGP00000001654 ENSGAGP00000001395 ENSGAGP00000001395 ENSGAGP00000001392 ENSGAGP00000001392 TICAM1 TICAM1 TOLLIP TOLLIP STAT1 STAT1 FOS FOS NFKB1 NFKB1 ENSGAGP00000000139 ENSGAGP00000000139 IKBKE IKBKE ENSGAGP00000012982 ENSGAGP00000012982 MAP2K3 MAP2K3 MAP3K8 MAP3K8 IKBKB IKBKB TRAF3 TRAF3 PIK3CA PIK3CA MAPK14 MAPK14 MYD88 MYD88 ENSGAGP00000011676 ENSGAGP00000011676 MAPK12 MAPK12 MAPK11 MAPK11 ENSGAGP00000011058 ENSGAGP00000011058 IKBKG IKBKG RELA RELA ENSGAGP00000009577 ENSGAGP00000009577 PIK3CB PIK3CB IL12A IL12A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LY96Lymphocyte antigen 96. (175 aa)
ENSGAGP00000036468Uncharacterized protein. (654 aa)
ENSGAGP00000036322IRF tryptophan pentad repeat domain-containing protein. (360 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (394 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (500 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (698 aa)
ENSGAGP00000033759Uncharacterized protein. (496 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
ENSGAGP00000009221annotation not available (187 aa)
TBK1TANK binding kinase 1. (661 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (450 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (313 aa)
ENSGAGP00000031386Uncharacterized protein. (463 aa)
AKT2Non-specific serine/threonine protein kinase. (673 aa)
ENSGAGP00000029623BZIP domain-containing protein. (367 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7. (614 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (438 aa)
AKT3Non-specific serine/threonine protein kinase. (524 aa)
ENSGAGP00000028746Uncharacterized protein. (472 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (419 aa)
ENSGAGP00000028590ANK_REP_REGION domain-containing protein. (325 aa)
FADDFas associated via death domain. (191 aa)
ENSGAGP00000026930Uncharacterized protein; Belongs to the peptidase C14A family. (483 aa)
ENSGAGP00000026688TIR domain-containing protein; Belongs to the Toll-like receptor family. (1050 aa)
ENSGAGP00000026680Uncharacterized protein. (249 aa)
ENSGAGP00000026676TIR domain-containing protein. (1003 aa)
TLR7Toll like receptor 7; Belongs to the Toll-like receptor family. (991 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (785 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (104 aa)
ENSGAGP00000025784TNFR-Cys domain-containing protein. (274 aa)
ENSGAGP00000025430Uncharacterized protein. (216 aa)
ENSGAGP00000025426Uncharacterized protein. (206 aa)
IFNAR1Interferon alpha and beta receptor subunit 1. (590 aa)
ENSGAGP00000025067Uncharacterized protein. (181 aa)
ENSGAGP00000024986Uncharacterized protein. (316 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (896 aa)
ENSGAGP00000022225Uncharacterized protein. (207 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (463 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (504 aa)
ENSGAGP00000021019Uncharacterized protein. (199 aa)
IRF7IRF tryptophan pentad repeat domain-containing protein. (634 aa)
ENSGAGP00000017572Uncharacterized protein. (168 aa)
ENSGAGP00000016699Uncharacterized protein. (174 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1046 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
ENSGAGP00000016239Uncharacterized protein. (189 aa)
ENSGAGP00000016238Uncharacterized protein. (189 aa)
ENSGAGP00000016236Uncharacterized protein. (187 aa)
CCL16C-C motif chemokine. (91 aa)
ENSGAGP00000015634C-C motif chemokine. (102 aa)
CCL5C-C motif chemokine. (135 aa)
ENSGAGP00000015630C-C motif chemokine. (218 aa)
ENSGAGP00000015040Uncharacterized protein. (577 aa)
ENSGAGP00000014753TIR domain-containing protein; Belongs to the Toll-like receptor family. (631 aa)
ENSGAGP00000014676TIR domain-containing protein. (673 aa)
ENSGAGP00000014455TIR domain-containing protein; Belongs to the Toll-like receptor family. (783 aa)
ENSGAGP00000014454TIR domain-containing protein; Belongs to the Toll-like receptor family. (797 aa)
IL6Interleukin 6. (214 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (743 aa)
IRF5Interferon regulatory factor 5. (501 aa)
ENSGAGP00000008157Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (466 aa)
TMED3Transmembrane p24 trafficking protein 3. (218 aa)
ENSGAGP00000007913Uncharacterized protein. (190 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (840 aa)
TIRAPTIR domain containing adaptor protein. (217 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
TNFTumor necrosis factor. (219 aa)
ENSGAGP00000007080MATH domain-containing protein. (140 aa)
ENSGAGP00000006929TIR domain-containing protein. (859 aa)
ENSGAGP00000006608Uncharacterized protein. (84 aa)
ENSGAGP00000006339Death domain-containing protein. (249 aa)
ENSGAGP00000006113TIR domain-containing protein. (222 aa)
MAPK10Mitogen-activated protein kinase. (461 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (435 aa)
ENSGAGP00000004868C-X-C motif chemokine. (100 aa)
IRF6Interferon regulatory factor 6. (460 aa)
ENSGAGP00000003436Uncharacterized protein. (175 aa)
ENSGAGP00000003429Uncharacterized protein. (191 aa)
ENSGAGP00000002241Uncharacterized protein. (475 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (460 aa)
ENSGAGP00000001654Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (353 aa)
ENSGAGP00000001395GOLD domain-containing protein. (225 aa)
ENSGAGP00000001392TIR domain-containing protein. (217 aa)
TICAM1TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (703 aa)
TOLLIPToll interacting protein. (281 aa)
STAT1Signal transducer and activator of transcription. (753 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (373 aa)
NFKB1Nuclear factor kappa B subunit 1. (981 aa)
ENSGAGP00000000139Uncharacterized protein. (508 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (724 aa)
ENSGAGP00000012982TIR domain-containing protein. (887 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (348 aa)
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (533 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (754 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (566 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (299 aa)
ENSGAGP00000011676Ig-like domain-containing protein. (302 aa)
MAPK12Mitogen-activated protein kinase. (361 aa)
MAPK11Mitogen-activated protein kinase. (361 aa)
ENSGAGP00000011058Uncharacterized protein; Belongs to the peptidase C1 family. (334 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (580 aa)
RELARELA proto-oncogene, NF-kB subunit. (555 aa)
ENSGAGP00000009577RING-type domain-containing protein. (38 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
IL12AInterleukin-12 subunit alpha; Belongs to the IL-6 superfamily. (209 aa)
Your Current Organism:
Gopherus agassizii
NCBI taxonomy Id: 38772
Other names: G. agassizii, Gopherus agassizi, Gopherus polyphemus agassizii, USNM 7888, desert tortoise
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