(84 nodes) Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S network (Medicago truncatula)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	G7IPP5_MEDTR	Dihydroflavonol-4-reductase-like protein. (343 aa)
	MTR_0164s0070	Dihydroflavonol reductase. (209 aa)
	MTR_0685s0030	Cinnamyl alcohol dehydrogenase. (164 aa)
	A0A072TRB7	Cinnamyl alcohol dehydrogenase. (326 aa)
	A0A072TRY5	Uncharacterized protein. (116 aa)
	A0A072U6Q4	Putative cinnamoyl-CoA reductase; Belongs to the 3-beta-HSD family. (358 aa)
	A0A072ULV1	Dihydroflavonol 4-reductase-like protein. (357 aa)
	A0A072UN75	Uncharacterized protein. (725 aa)
	A0A072URR3	DEAD-box ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. (430 aa)
	A0A072V0U1	B3 DNA-binding domain protein. (251 aa)
	A0A072V980	DEAD-box ATP-dependent RNA helicase. (552 aa)
	A0A072VDF2	Cinnamoyl-CoA reductase-like protein. (342 aa)
	A0A072VDG5	Putative transcription factor B3-Domain family. (372 aa)
	A0A072VF37	B3 DNA-binding domain protein. (221 aa)
	A0A072VFE7	B3 domain transcription factor VRN1-like protein. (433 aa)
	A0A072VG30	B3 domain transcription factor VRN1-like protein. (370 aa)
	A0A072VGJ6	Putative transcription factor B3-Domain family. (324 aa)
	A0A072VGK8	Plant-specific B3-DNA-binding domain protein. (335 aa)
	A0A072VGM5	DEAD-box ATP-dependent RNA helicase. (398 aa)
	A2Q3W4_MEDTR	Dihydroflavonol 4-reductase-like protein. (326 aa)
	A2Q3Y0_MEDTR	NAD-dependent epimerase/dehydratase family protein. (70 aa)
	A2Q3Y3_MEDTR	Dihydroflavonol 4-reductase-like protein. (326 aa)
	A2Q689_MEDTR	DEAD-box ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. (413 aa)
	B7FHA3_MEDTR	40S ribosomal protein S27. (86 aa)
	B7FL50_MEDTR	DEAD-box ATP-dependent RNA helicase. (480 aa)
	B7FM90_MEDTR	Putative PetM of cytochrome b6/f complex subunit 7. (127 aa)
	B7FN54_MEDTR	40S ribosomal protein S27. (86 aa)
	G7I4K0_MEDTR	Putative transcription factor B3-Domain family. (596 aa)
	G7I4K2_MEDTR	Plant-specific B3-DNA-binding domain protein. (347 aa)
	G7I4K4_MEDTR	Putative transcription factor B3-Domain family. (842 aa)
	G7I4K5_MEDTR	Plant-specific B3-DNA-binding domain protein. (385 aa)
	G7I4K7_MEDTR	Plant-specific B3-DNA-binding domain protein. (348 aa)
	G7I4K8_MEDTR	Putative transcription factor B3-Domain family. (478 aa)
	G7I4K9_MEDTR	Plant-specific B3-DNA-binding domain protein. (350 aa)
	G7I576_MEDTR	Plant-specific B3-DNA-binding domain protein. (368 aa)
	G7I577_MEDTR	Putative transcription factor B3-Domain family. (361 aa)
	G7I584_MEDTR	Plant-specific B3-DNA-binding domain protein. (491 aa)
	G7ID23_MEDTR	Transmembrane protein, putative. (181 aa)
	G7IFT8_MEDTR	Putative cinnamoyl-CoA reductase. (333 aa)
	G7IJA0_MEDTR	Ribosome silencing factor. (249 aa)
	G7IPP8_MEDTR	Dihydroflavonol-4-reductase-like protein. (341 aa)
	G7IPP9_MEDTR	Putative anthocyanidin reductase ((2R,3R)-flavan-3-ol-forming). (352 aa)
	G7IS33_MEDTR	DEAD-box ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. (413 aa)
	G7IUM5_MEDTR	Putative NAD(P)-binding domain, tetraketide alpha-pyrone reductase 1. (330 aa)
	G7IVR3_MEDTR	Cinnamyl alcohol dehydrogenase, putative. (146 aa)
	G7IYC1_MEDTR	Cinnamyl-alcohol dehydrogenase-like protein. (326 aa)
	G7IYC6_MEDTR	Cinnamyl-alcohol dehydrogenase-like protein. (322 aa)
	G7IYF3_MEDTR	Putative translation initiation factor 1A (eIF-1A), RNA-binding domain, S1, IF1 type; Belongs to the eIF-1A family. (150 aa)
	G7IZT5_MEDTR	Putative cinnamoyl-CoA reductase. (326 aa)
	G7J0Q8_MEDTR	Cinnamoyl-CoA reductase-like protein. (319 aa)
	G7J6B7_MEDTR	Putative farnesol dehydrogenase (NAD(+)). (333 aa)
	G7JDF6_MEDTR	Dihydroflavonol 4-reductase-like protein. (329 aa)
	G7JEE5_MEDTR	Cinnamoyl-CoA reductase-like protein. (336 aa)
	G7JEX9_MEDTR	B3 DNA-binding domain protein. (273 aa)
	G7JEY1_MEDTR	B3 domain transcription factor VRN1-like protein. (429 aa)
	G7JFN2_MEDTR	Cinnamoyl-CoA reductase. (330 aa)
	G7JNT5_MEDTR	Transmembrane protein, putative. (261 aa)
	G7JPL7_MEDTR	Putative transcription factor NAM family. (299 aa)
	G7JRN6_MEDTR	Putative NAD(P)-binding domain-containing protein. (327 aa)
	G7JRN8_MEDTR	Putative NAD(P)-binding domain-containing protein. (325 aa)
	G7JRP0_MEDTR	Cinnamyl alcohol dehydrogenase, putative. (169 aa)
	G7JRP1_MEDTR	Uncharacterized protein. (502 aa)
	G7JYE9_MEDTR	Hydroxyproline-rich glycoprotein family protein, putative. (317 aa)
	G7K1K4_MEDTR	Putative NAD(P)-binding domain-containing protein. (319 aa)
	G7KDR3_MEDTR	Cinnamoyl-CoA reductase-like protein. (298 aa)
	G7KEC3_MEDTR	Cinnamoyl-CoA reductase-like protein. (320 aa)
	G7KZA8_MEDTR	Dihydroflavonol 4-reductase-like protein. (328 aa)
	G7KZB6_MEDTR	Putative vestitone reductase. (329 aa)
	G7KZB8_MEDTR	Dihydroflavonol 4-reductase-like protein. (329 aa)
	G7KZC0_MEDTR	Putative vestitone reductase. (288 aa)
	G7L425_MEDTR	Putative anthocyanidin reductase ((2R,3R)-flavan-3-ol-forming). (340 aa)
	G7L911_MEDTR	Transcriptional factor B3 family protein. (498 aa)
	G7LDS7_MEDTR	Dentin sialophosphoprotein, putative. (742 aa)
	G7LDU4_MEDTR	Cinnamyl alcohol dehydrogenase. (333 aa)
	G7LEN3_MEDTR	Uncharacterized protein. (130 aa)
	G7LEQ3_MEDTR	Cinnamoyl-CoA reductase, putative. (123 aa)
	G7LI88_MEDTR	Eukaryotic translation initiation factor 4A1. (177 aa)
	G7LI90_MEDTR	Eukaryotic translation initiation factor 4A1. (176 aa)
	G7LI92_MEDTR	DEAD-box ATP-dependent RNA helicase. (325 aa)
	G7LI94_MEDTR	DEAD-box ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. (413 aa)
	G7ZYQ6_MEDTR	Eukaryotic translation initiation factor 1A-like protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (146 aa)
	Q6TQT0_MEDTR	Dihydroflavonol 4-reductase-like protein. (339 aa)
	Q6TQT1_MEDTR	Putative dihydroflavanol 4-reductase. (334 aa)
	BAN	Putative anthocyanidin reductase ((2R,3R)-flavan-3-ol-forming). (338 aa)

Your Current Organism:

Medicago truncatula

NCBI taxonomy Id: 3880
Other names: M. truncatula, Medicago truncatula Gaertn., barrel medic

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A072TRY5	A0A072V0U1	A0A072TRY5	A0A072V0U1	Uncharacterized protein.	B3 DNA-binding domain protein.	0.515
A0A072TRY5	G7JEX9_MEDTR	A0A072TRY5	G7JEX9	Uncharacterized protein.	B3 DNA-binding domain protein.	0.622
A0A072U6Q4	G7L425_MEDTR	A0A072U6Q4	G7L425	Putative cinnamoyl-CoA reductase; Belongs to the 3-beta-HSD family.	Putative anthocyanidin reductase ((2R,3R)-flavan-3-ol-forming).	0.520
A0A072U6Q4	MTR_0685s0030	A0A072U6Q4	A0A072TQ04	Putative cinnamoyl-CoA reductase; Belongs to the 3-beta-HSD family.	Cinnamyl alcohol dehydrogenase.	0.402
A0A072URR3	G7IYF3_MEDTR	A0A072URR3	G7IYF3	DEAD-box ATP-dependent RNA helicase; Belongs to the DEAD box helicase family.	Putative translation initiation factor 1A (eIF-1A), RNA-binding domain, S1, IF1 type; Belongs to the eIF-1A family.	0.530
A0A072URR3	G7ZYQ6_MEDTR	A0A072URR3	G7ZYQ6	DEAD-box ATP-dependent RNA helicase; Belongs to the DEAD box helicase family.	Eukaryotic translation initiation factor 1A-like protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	0.530
A0A072V0U1	A0A072TRY5	A0A072V0U1	A0A072TRY5	B3 DNA-binding domain protein.	Uncharacterized protein.	0.515
A0A072V0U1	G7IYF3_MEDTR	A0A072V0U1	G7IYF3	B3 DNA-binding domain protein.	Putative translation initiation factor 1A (eIF-1A), RNA-binding domain, S1, IF1 type; Belongs to the eIF-1A family.	0.707
A0A072V0U1	G7JNT5_MEDTR	A0A072V0U1	G7JNT5	B3 DNA-binding domain protein.	Transmembrane protein, putative.	0.602
A0A072V0U1	G7ZYQ6_MEDTR	A0A072V0U1	G7ZYQ6	B3 DNA-binding domain protein.	Eukaryotic translation initiation factor 1A-like protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	0.707
A0A072V980	G7IYF3_MEDTR	A0A072V980	G7IYF3	DEAD-box ATP-dependent RNA helicase.	Putative translation initiation factor 1A (eIF-1A), RNA-binding domain, S1, IF1 type; Belongs to the eIF-1A family.	0.530
A0A072V980	G7LI90_MEDTR	A0A072V980	G7LI90	DEAD-box ATP-dependent RNA helicase.	Eukaryotic translation initiation factor 4A1.	0.451
A0A072V980	G7ZYQ6_MEDTR	A0A072V980	G7ZYQ6	DEAD-box ATP-dependent RNA helicase.	Eukaryotic translation initiation factor 1A-like protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	0.530
A0A072VDF2	G7JEE5_MEDTR	A0A072VDF2	G7JEE5	Cinnamoyl-CoA reductase-like protein.	Cinnamoyl-CoA reductase-like protein.	0.901
A0A072VDG5	G7IYF3_MEDTR	A0A072VDG5	G7IYF3	Putative transcription factor B3-Domain family.	Putative translation initiation factor 1A (eIF-1A), RNA-binding domain, S1, IF1 type; Belongs to the eIF-1A family.	0.707
A0A072VDG5	G7JRP1_MEDTR	A0A072VDG5	G7JRP1	Putative transcription factor B3-Domain family.	Uncharacterized protein.	0.460
A0A072VDG5	G7LEN3_MEDTR	A0A072VDG5	G7LEN3	Putative transcription factor B3-Domain family.	Uncharacterized protein.	0.562
A0A072VDG5	G7ZYQ6_MEDTR	A0A072VDG5	G7ZYQ6	Putative transcription factor B3-Domain family.	Eukaryotic translation initiation factor 1A-like protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.	0.707
A0A072VF37	G7IYF3_MEDTR	A0A072VF37	G7IYF3	B3 DNA-binding domain protein.	Putative translation initiation factor 1A (eIF-1A), RNA-binding domain, S1, IF1 type; Belongs to the eIF-1A family.	0.707
A0A072VF37	G7JRP1_MEDTR	A0A072VF37	G7JRP1	B3 DNA-binding domain protein.	Uncharacterized protein.	0.451