STRINGSTRING
PNK_0011 PNK_0011 tal1 tal1 PNK_0022 PNK_0022 PNK_0024 PNK_0024 PNK_0025 PNK_0025 PNK_0026 PNK_0026 fixN fixN fixO fixO aspc1 aspc1 eno eno PNK_0139 PNK_0139 PNK_0140 PNK_0140 lpdA1 lpdA1 lipA lipA pgma1 pgma1 birA birA PNK_0173 PNK_0173 PNK_0237 PNK_0237 pgk pgk gdhB gdhB pckG pckG ackA ackA gnd gnd PNK_0485 PNK_0485 PNK_0539 PNK_0539 plsX plsX sucC sucC sucD sucD PNK_0592 PNK_0592 PNK_0593 PNK_0593 PNK_0596 PNK_0596 glnA glnA fabF fabF aas aas PNK_0667 PNK_0667 cyoE cyoE cyoD cyoD cyoC cyoC cyoB cyoB cyoA cyoA PNK_0673 PNK_0673 rpiA rpiA accA accA PNK_0711 PNK_0711 pgma3 pgma3 fabI fabI deoC deoC sucA sucA sucB sucB lpdA2 lpdA2 fdiv1 fdiv1 mdh1 mdh1 gltA gltA pdhA pdhA pdhB pdhB pdhC pdhC fabH fabH fabD fabD fabg1 fabg1 acpP acpP putP putP opuE opuE acpS acpS PNK_0929 PNK_0929 folD folD tpiA tpiA pgl pgl PNK_0975 PNK_0975 zwf zwf PNK_1006 PNK_1006 PNK_1091 PNK_1091 PNK_1092 PNK_1092 PNK_1093 PNK_1093 PNK_1112 PNK_1112 PNK_1119 PNK_1119 fbaB fbaB rbp rbp pfkA pfkA PNK_1262 PNK_1262 PNK_1263 PNK_1263 acs acs PNK_1322 PNK_1322 accC1 accC1 accB accB rpe rpe PNK_1420 PNK_1420 PNK_1464 PNK_1464 PNK_1466 PNK_1466 PNK_1474 PNK_1474 pgi pgi PNK_1543 PNK_1543 PNK_1544 PNK_1544 astA astA astD astD astB astB PNK_1548 PNK_1548 hprK hprK mdh3 mdh3 prs prs cydB cydB cydA cydA pyk pyk fumC fumC tal3 tal3 PNK_1743 PNK_1743 nuoN nuoN nuoM nuoM nuoL nuoL nuoK nuoK nuoJ nuoJ nuoI nuoI nuoH nuoH nuoG nuoG nuoF nuoF nuoE nuoE nuoD nuoD nuoC nuoC nuoB nuoB nuoA nuoA PNK_1758 PNK_1758 PNK_1759 PNK_1759 PNK_1760 PNK_1760 PNK_1782 PNK_1782 PNK_1783 PNK_1783 bioD bioD bioF bioF bioB bioB PNK_1788 PNK_1788 PNK_1795 PNK_1795 aldA aldA PNK_1858 PNK_1858 acsA acsA PNK_1864 PNK_1864 PNK_1870 PNK_1870 glyA glyA gapA gapA fmt fmt fdiv3 fdiv3 gcvPB gcvPB gcvPA gcvPA gcvH gcvH gcvT gcvT lplA lplA accD accD tkt tkt icd icd prsA prsA dctA dctA PNK_2160 PNK_2160 panF panF bioY bioY PNK_2198 PNK_2198 sdhB sdhB sdhA sdhA sdhC sdhC PNK_2290 PNK_2290 fliY fliY putA putA fabg3 fabg3 xpk1 xpk1 PNK_2458 PNK_2458
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PNK_0011Putative acylphosphatase. (97 aa)
tal1Putative transaldolase. (220 aa)
PNK_0022Putative Pyridine nucleotide-disulphide oxidoreductase. (614 aa)
PNK_0024Hypothetical protein. (170 aa)
PNK_0025Cytochrome b/b6 domain-containing protein. (441 aa)
PNK_0026Hypothetical protein. (1390 aa)
fixNPutative cytochrome c oxidase, subunit I; Belongs to the heme-copper respiratory oxidase family. (477 aa)
fixOPutative cytochrome oxidase, cytochrome c subunit. (429 aa)
aspc1Aspartate aminotransferase. (397 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (439 aa)
PNK_0139Conserved hypothetical protein. (102 aa)
PNK_0140Hypothetical protein; Hydrolases of the alpha/beta superfamily. (418 aa)
lpdA1Dihydrolipoamide dehydrogenase. (469 aa)
lipALipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (328 aa)
pgma1Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (225 aa)
birAPutative biotin-[acetyl-CoA-carboxylase] ligase. (257 aa)
PNK_0173Putative carbohydrate kinase, PfkB family. (364 aa)
PNK_0237Conserved hypothetical protein; tRNA and rRNA cytosine-C5-methylases. (392 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (408 aa)
gdhBEucaryotic NAD-specific glutamate dehydrogenase. (1026 aa)
pckGPhosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (594 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (397 aa)
gnd6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (482 aa)
PNK_0485Short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (288 aa)
PNK_0539Conserved hypothetical protein. (631 aa)
plsXPutative fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (338 aa)
sucCsuccinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (386 aa)
sucDsuccinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (295 aa)
PNK_0592Hypothetical protein. (722 aa)
PNK_0593Short-chain dehydrogenase/reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (261 aa)
PNK_0596Conserved hypothetical protein. (712 aa)
glnAGlutamine synthetase. (727 aa)
fabF3-oxoacyl-[acyl-carrier-protein] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (415 aa)
aasAcylglycerophosphoethanolamine acyltransferase. (910 aa)
PNK_0667Hypothetical protein. (543 aa)
cyoEProtoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (281 aa)
cyoDPutative cytochrome o ubiquinol oxidase, subunit IV. (119 aa)
cyoCCytochrome o ubiquinol oxidase subunit 3. (210 aa)
cyoBUbiquinol oxidase subunit 1; Belongs to the heme-copper respiratory oxidase family. (657 aa)
cyoACytochrome o ubiquinol oxidase, subunit II. (292 aa)
PNK_0673Conserved hypothetical protein. (94 aa)
rpiARibose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (232 aa)
accAacetyl-CoA carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (316 aa)
PNK_0711Short-chain dehydrogenase/reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (237 aa)
pgma3Putative phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. (208 aa)
fabIEnoyl-[acyl-carrier-protein] reductase [NADH]. (303 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (219 aa)
sucA2-oxoglutarate dehydrogenase E1 component. (908 aa)
sucB2-oxogluturate dehydrogenase complex E2 component. (396 aa)
lpdA22-oxoglutarate dehydrogenase E3 component. (465 aa)
fdiv1Putative ferredoxin [2Fe-2S] 4. (88 aa)
mdh1Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (328 aa)
gltAPutative type 1 citrate synthase; Belongs to the citrate synthase family. (389 aa)
pdhAPyruvate dehydrogenase, E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (306 aa)
pdhBPyruvate dehydrogenase, E1 component, beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (328 aa)
pdhCDihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (432 aa)
fabH3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (332 aa)
fabDMalonyl CoA-acyl carrier protein transacylase. (316 aa)
fabg13-oxoacyl-[acyl-carrier-protein] reductase protein FabG; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (250 aa)
acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (77 aa)
putPSodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (488 aa)
opuEPutative sodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (484 aa)
acpSHolo-[acyl-carrier-protein] synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (127 aa)
PNK_0929Conserved hypothetical protein; Belongs to the ribose-phosphate pyrophosphokinase family. (304 aa)
folDMethenyltetrahydrofolate cyclohydrolase/methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (292 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (261 aa)
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (260 aa)
PNK_0975Glucose-6-phosphate dehydrogenase family protein. (359 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (532 aa)
PNK_1006FAD dependent oxidoreductase. (513 aa)
PNK_1091Hypothetical protein. (73 aa)
PNK_1092Hypothetical protein. (72 aa)
PNK_1093Short-chain dehydrogenase/reductase. (241 aa)
PNK_1112Putative short-chain dehydrogenase/reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (238 aa)
PNK_1119ROK family protein. (337 aa)
fbaBFructose-bisphosphate aldolase. (352 aa)
rbpRNA-binding protein. (108 aa)
pfkAPhosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (556 aa)
PNK_1262Carboxyl transferase-family protein. (920 aa)
PNK_12633-oxoacyl-ACP synthase. (387 aa)
acsAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (630 aa)
PNK_1322Short-chain dehydrogenase/reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (249 aa)
accC1Biotin carboxylase 1; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (452 aa)
accBacetyl-CoA carboxylase biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (169 aa)
rpeRibulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (243 aa)
PNK_1420Conserved hypothetical protein. (344 aa)
PNK_1464Hypothetical protein. (113 aa)
PNK_1466Putative metalloprotease. (428 aa)
PNK_1474Hypothetical protein. (369 aa)
pgiGlucose-6-phosphate isomerase; Belongs to the GPI family. (541 aa)
PNK_1543Putative carboxypeptidase G2. (414 aa)
PNK_1544Hypothetical protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (464 aa)
astAPutative Arginine N-succinyltransferase beta subunit. (338 aa)
astDSuccinylglutamic semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (499 aa)
astBSuccinylarginine dihydrolase. (458 aa)
PNK_1548Hypothetical protein. (958 aa)
hprKHPr Serine kinase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). (316 aa)
mdh3Putative malate dehydrogenase; Belongs to the LDH/MDH superfamily. (325 aa)
prsRibose-phosphate pyrophosphokinase. (314 aa)
cydBCytochrome bd-I oxidase subunit II. (343 aa)
cydACytochrome bd-I oxidase subunit I; Belongs to the cytochrome ubiquinol oxidase subunit 1 family. (464 aa)
pykPyruvate kinase; Belongs to the pyruvate kinase family. (589 aa)
fumCFumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (463 aa)
tal3Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (322 aa)
PNK_1743Putative nudix hydrolase. (153 aa)
nuoNPutative NADH-ubiquinone oxidoreductase chain N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (480 aa)
nuoMNADH-ubiquinone oxidoreductase chain M. (489 aa)
nuoLNADH-ubiquinone oxidoreductase subunit L. (628 aa)
nuoKNADH dehydrogenase I, K subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. (99 aa)
nuoJPutative NADH-ubiquinone/plastoquinone oxidoreductase, chain 6; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (169 aa)
nuoINADH dehydrogenase I, chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (157 aa)
nuoHNADH dehydrogenase I, H subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. (325 aa)
nuoGNADH-ubiquinone oxidoreductase subunit G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. (770 aa)
nuoFNADH-ubiquinone oxidoreductase subunit F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family. (432 aa)
nuoEPutative NADH dehydrogenase I, chain E. (171 aa)
nuoDNADH dehydrogenase I, D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family. (402 aa)
nuoCPutative NADH dehydrogenase, subunit C; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family. (180 aa)
nuoBNADH-quinone oxidoreductase subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (161 aa)
nuoAPutative NADH dehydrogenase I, chain A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family. (118 aa)
PNK_1758Hypothetical protein. (526 aa)
PNK_1759Putative acetyltransferase. (201 aa)
PNK_1760Putative hydrolase. (257 aa)
PNK_1782Hypothetical protein. (207 aa)
PNK_1783Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (434 aa)
bioDDethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (211 aa)
bioF8-amino-7-oxononanoate synthase. (371 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (323 aa)
PNK_1788Hypothetical protein; Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1. (342 aa)
PNK_1795Uncharacterized protein conserved in bacteria. (130 aa)
aldAAldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (506 aa)
PNK_1858Short-chain dehydrogenase/reductase. (253 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (650 aa)
PNK_1864Hypothetical protein. (392 aa)
PNK_1870Short-chain dehydrogenase/reductase. (250 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (491 aa)
gapAglyceraldehyde-3-P dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (341 aa)
fmtMethionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (318 aa)
fdiv3Putative ferredoxin [2Fe-2S] 4. (93 aa)
gcvPBPutative glycine dehydrogenase (decarboxylating) subunit 2. (481 aa)
gcvPAGlycine cleavage system P-protein subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (446 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (122 aa)
gcvTAminomethyltransferase. (359 aa)
lplAPutative lipoate-protein ligase A. (237 aa)
accDacetyl-CoA carboxylase, subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (302 aa)
tktTransketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (685 aa)
icdIsocitrate dehydrogenase. (482 aa)
prsAPutative Ribose-phosphate pyrophosphokinase. (349 aa)
dctAPutative C4-dicarboxylate transport protein; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (410 aa)
PNK_2160Pyridine nucleotide-disulphide oxidoreductase family protein. (415 aa)
panFSodium/pantothenate symporter (pantothenate permease); Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (375 aa)
bioYPutative biotin transporter BioY. (194 aa)
PNK_2198Putative lipoate-protein ligase A. (239 aa)
sdhBSuccinate dehydrogenase iron-sulfur subunit. (256 aa)
sdhASuccinate dehydrogenase flavoprotein subunit. (630 aa)
sdhCPutative succinate dehydrogenase cytochrome b-558 subunit. (320 aa)
PNK_2290Lipase. (334 aa)
fliYAmino acid ABC transporter substrate-binding protein. (277 aa)
putABifunctional protein (proline dehydrogenase and delta-1-pyrroline-5-carboxylate dehydrogenase); Belongs to the aldehyde dehydrogenase family. (1221 aa)
fabg3Putative 3-oxoacyl-[acyl-carrier-protein] reductase. (278 aa)
xpk1D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase. (799 aa)
PNK_2458Putative sodium/solute simporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (488 aa)
Your Current Organism:
Protochlamydia naegleriophila
NCBI taxonomy Id: 389348
Other names: C. Protochlamydia naegleriophila, Candidatus Protochlamydia naegleriophila, strain KNic
Server load: low (12%) [HD]