STRINGSTRING
ddl ddl murA murA murF murF alr alr Ldb0365 Ldb0365 truA truA murB murB murE2 murE2 prfA prfA hemK hemK Ldb0703 Ldb0703 Ldb0713 Ldb0713 mreB2 mreB2 Ldb0715 Ldb0715 Ldb0716 Ldb0716 rodA rodA Ldb0724 Ldb0724 thiI thiI rsuA rsuA valS valS folC1 folC1 Ldb0729 Ldb0729 radC radC mreB1 mreB1 mreC mreC Ldb0734 Ldb0734 mraZ mraZ mraW mraW ftsL ftsL ftsI ftsI mraY mraY murD murD murG murG ftsQ ftsQ ftsA ftsA ftsZ ftsZ sepF sepF Ldb0747 Ldb0747 cspB cspB Ldb0751 Ldb0751 Ldb0753 Ldb0753 Ldb0754 Ldb0754 trmU trmU Ldb0756 Ldb0756 Ldb0757 Ldb0757 recD recD ftsW ftsW Ldb0827 Ldb0827 pbp1A pbp1A Ldb1182 Ldb1182 murC murC pbp2A pbp2A dacA dacA ppsA ppsA murE murE Ldb2100 Ldb2100
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ddlD-alanine--D-alanine ligase; Cell wall formation. (362 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (423 aa)
murFUDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (455 aa)
alrAlanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (376 aa)
Ldb0365Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms. (126 aa)
truAtRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (263 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (297 aa)
murE2Putative UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase. (451 aa)
prfAPeptide chain release factor 1 (RF-1); Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (361 aa)
hemKMethylase of polypeptide chain release factors. (273 aa)
Ldb0703Putative translation factor (Sua5 family); Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (331 aa)
Ldb0713Conserved hypothetical membrane protein. (81 aa)
mreB2Cell-shape-determining protein MreB. (329 aa)
Ldb0715Conserved hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. (95 aa)
Ldb0716Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms. (75 aa)
rodARod-shape determining protein; Belongs to the SEDS family. (396 aa)
Ldb0724Putative cysteine sulfinate desulfinase/cysteine desulfurase. (385 aa)
thiIThiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (399 aa)
rsuAPseudouridylate synthase; Belongs to the pseudouridine synthase RsuA family. (241 aa)
valSValyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (879 aa)
folC1Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. (421 aa)
Ldb0729Putative phosphatase. (226 aa)
radCDNA repair protein RadC. (204 aa)
mreB1Cell-shape-determining protein MreB. (334 aa)
mreCCell shape determining protein MreC; Involved in formation and maintenance of cell shape. (274 aa)
Ldb0734Conserved hypothetical membrane protein. (109 aa)
mraZCell division protein MraZ; Belongs to the MraZ family. (143 aa)
mraWS-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (314 aa)
ftsLCell division protein FtsL; Essential cell division protein; Belongs to the FtsL family. (118 aa)
ftsICell division protein FtsI; Penicillin-binding protein. (720 aa)
mraYPhospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (319 aa)
murDUDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (460 aa)
murGUndecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (370 aa)
ftsQCell division protein FtsQ; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily. (281 aa)
ftsACell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. (460 aa)
ftsZCell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (452 aa)
sepFConserved hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. (138 aa)
Ldb0747Putative RNA binding protein. (265 aa)
cspBCold shock protein B. (69 aa)
Ldb07516 Protein of unknown function, without similarity to other proteins. (68 aa)
Ldb0753Putative cysteine sulfinate desulfinase/cysteine desulfurase. (387 aa)
Ldb0754Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms. (113 aa)
trmUtRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (375 aa)
Ldb0756Putative fructose-2,6-bisphosphatase. (219 aa)
Ldb0757Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms. (217 aa)
recDExodeoxyribonuclease V alpha chain; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. (796 aa)
ftsWCell division protein FtsW; Belongs to the SEDS family. (400 aa)
Ldb0827Conserved hypothetical membrane protein (fragment); Belongs to the UPF0340 family. (187 aa)
pbp1APenicillin-binding protein 1A; Bifunctional protein (transglycosylase/transpeptidase). (777 aa)
Ldb1182Transcriptional regulator (DeoR family). (153 aa)
murCPutative transcriptional regulator (AraC family) (fragment); Cell wall formation; Belongs to the MurCDEF family. (439 aa)
pbp2APenicillin-binding protein 2A; Bifunctional protein (transglycosylase/transpeptidase). (695 aa)
dacAD-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. (428 aa)
ppsAPhosphoenolpyruvate synthase (fragment). (539 aa)
murEUDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan; Belongs to the MurCDEF family. MurE subfamily. (516 aa)
Ldb2100Glycerol kinase (fragment). (222 aa)
Your Current Organism:
Lactobacillus delbrueckii
NCBI taxonomy Id: 390333
Other names: L. delbrueckii subsp. bulgaricus ATCC 11842 = JCM 1002, Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842, Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842 = JCM 1002, Lactobacillus delbrueckii subsp. bulgaricus DSM 20081
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