STRINGSTRING
ddl ddl murA murA murF murF alr alr Ldb0365 Ldb0365 murB murB valS valS folC1 folC1 Ldb0729 Ldb0729 radC radC mreB1 mreB1 mreC mreC Ldb0734 Ldb0734 mraZ mraZ mraW mraW ftsL ftsL ftsI ftsI mraY mraY murD murD murG murG ftsQ ftsQ ftsA ftsA ftsZ ftsZ sepF sepF Ldb0747 Ldb0747 ftsW ftsW pbp1A pbp1A murC murC pbp2A pbp2A dacA dacA murE murE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ddlD-alanine--D-alanine ligase; Cell wall formation. (362 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (423 aa)
murFUDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (455 aa)
alrAlanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (376 aa)
Ldb0365Conserved hypothetical protein; 5.2 Protein of unknown function similar to proteins from other organisms. (126 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (297 aa)
valSValyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (879 aa)
folC1Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. (421 aa)
Ldb0729Putative phosphatase. (226 aa)
radCDNA repair protein RadC. (204 aa)
mreB1Cell-shape-determining protein MreB. (334 aa)
mreCCell shape determining protein MreC; Involved in formation and maintenance of cell shape. (274 aa)
Ldb0734Conserved hypothetical membrane protein. (109 aa)
mraZCell division protein MraZ; Belongs to the MraZ family. (143 aa)
mraWS-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (314 aa)
ftsLCell division protein FtsL; Essential cell division protein; Belongs to the FtsL family. (118 aa)
ftsICell division protein FtsI; Penicillin-binding protein. (720 aa)
mraYPhospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (319 aa)
murDUDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (460 aa)
murGUndecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (370 aa)
ftsQCell division protein FtsQ; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily. (281 aa)
ftsACell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. (460 aa)
ftsZCell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (452 aa)
sepFConserved hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. (138 aa)
Ldb0747Putative RNA binding protein. (265 aa)
ftsWCell division protein FtsW; Belongs to the SEDS family. (400 aa)
pbp1APenicillin-binding protein 1A; Bifunctional protein (transglycosylase/transpeptidase). (777 aa)
murCPutative transcriptional regulator (AraC family) (fragment); Cell wall formation; Belongs to the MurCDEF family. (439 aa)
pbp2APenicillin-binding protein 2A; Bifunctional protein (transglycosylase/transpeptidase). (695 aa)
dacAD-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. (428 aa)
murEUDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan; Belongs to the MurCDEF family. MurE subfamily. (516 aa)
Your Current Organism:
Lactobacillus delbrueckii
NCBI taxonomy Id: 390333
Other names: L. delbrueckii subsp. bulgaricus ATCC 11842 = JCM 1002, Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842, Lactobacillus delbrueckii subsp. bulgaricus ATCC 11842 = JCM 1002, Lactobacillus delbrueckii subsp. bulgaricus DSM 20081
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.