STRINGSTRING
Smal_0002 Smal_0002 Smal_0012 Smal_0012 Smal_0026 Smal_0026 tdk tdk Smal_0062 Smal_0062 Smal_0106 Smal_0106 Smal_0117 Smal_0117 Smal_0122 Smal_0122 Smal_0151 Smal_0151 Smal_0156 Smal_0156 Smal_0175 Smal_0175 Smal_0190 Smal_0190 Smal_0230 Smal_0230 coaX coaX Smal_0257 Smal_0257 Smal_0288 Smal_0288 anmK anmK dnaG dnaG glnE glnE Smal_0380 Smal_0380 Smal_0384 Smal_0384 Smal_0420 Smal_0420 Smal_0447 Smal_0447 dinB dinB Smal_0471 Smal_0471 Smal_0472 Smal_0472 Smal_0504 Smal_0504 Smal_0508 Smal_0508 Smal_0529 Smal_0529 Smal_0535 Smal_0535 thiL thiL mraY mraY Smal_0616 Smal_0616 Smal_0619 Smal_0619 rbsK rbsK Smal_0653 Smal_0653 Smal_0655 Smal_0655 Smal_0718 Smal_0718 ispE ispE prs prs Smal_0737 Smal_0737 Smal_0738 Smal_0738 rpoB rpoB rpoC rpoC rpoA rpoA Smal_0798 Smal_0798 ppk ppk Smal_0823 Smal_0823 dnaQ dnaQ kdkA kdkA dnaX dnaX Smal_0870 Smal_0870 tmk tmk Smal_0878 Smal_0878 Smal_0900 Smal_0900 Smal_0918 Smal_0918 Smal_0947 Smal_0947 Smal_0949 Smal_0949 hprK hprK Smal_0952 Smal_0952 Smal_0954 Smal_0954 Smal_0975 Smal_0975 Smal_1011 Smal_1011 Smal_1030 Smal_1030 Smal_1031 Smal_1031 Smal_1051 Smal_1051 Smal_1056 Smal_1056 mdcB mdcB Smal_1077 Smal_1077 Smal_1098 Smal_1098 Smal_1124 Smal_1124 Smal_1189 Smal_1189 Smal_1194 Smal_1194 Smal_1205 Smal_1205 Smal_1226 Smal_1226 Smal_1227 Smal_1227 Smal_1229 Smal_1229 Smal_1245 Smal_1245 Smal_1251 Smal_1251 Smal_1260 Smal_1260 pyrH pyrH Smal_1264 Smal_1264 glnD glnD Smal_1300 Smal_1300 Smal_1301 Smal_1301 Smal_1334 Smal_1334 Smal_1335 Smal_1335 Smal_1337 Smal_1337 Smal_1366 Smal_1366 Smal_1369 Smal_1369 Smal_1394 Smal_1394 lpxK lpxK kdsB kdsB Smal_1404 Smal_1404 ispD ispD Smal_1474 Smal_1474 Smal_1505 Smal_1505 pcnB pcnB Smal_1516 Smal_1516 Smal_1523 Smal_1523 glk glk coaD coaD Smal_1604 Smal_1604 Smal_1611 Smal_1611 selO selO cmk cmk Smal_1650 Smal_1650 Smal_1652 Smal_1652 ndk ndk Smal_1717 Smal_1717 Smal_1721 Smal_1721 Smal_1735 Smal_1735 Smal_1736 Smal_1736 Smal_1737 Smal_1737 Smal_1740 Smal_1740 Smal_1749 Smal_1749 thrB thrB Smal_1766 Smal_1766 Smal_1777 Smal_1777 Smal_1791 Smal_1791 Smal_1852 Smal_1852 Smal_1859 Smal_1859 fliA fliA Smal_1885 Smal_1885 Smal_1911 Smal_1911 Smal_1912 Smal_1912 Smal_1914 Smal_1914 Smal_1923 Smal_1923 Smal_1948 Smal_1948 Smal_1989 Smal_1989 Smal_2030 Smal_2030 Smal_2031 Smal_2031 Smal_2032 Smal_2032 Smal_2060 Smal_2060 Smal_2114 Smal_2114 Smal_2119 Smal_2119 Smal_2130 Smal_2130 Smal_2138 Smal_2138 Smal_2166 Smal_2166 Smal_2173 Smal_2173 Smal_2180 Smal_2180 Smal_2182 Smal_2182 Smal_2224 Smal_2224 Smal_2239 Smal_2239 Smal_2262 Smal_2262 Smal_2275 Smal_2275 Smal_2339 Smal_2339 Smal_2343 Smal_2343 Smal_2379 Smal_2379 dnaE2 dnaE2 Smal_2404 Smal_2404 Smal_2409 Smal_2409 Smal_2413 Smal_2413 Smal_2417 Smal_2417 Smal_2421 Smal_2421 Smal_2422 Smal_2422 Smal_2464 Smal_2464 Smal_2571 Smal_2571 nadK nadK slyX slyX proB proB Smal_2726 Smal_2726 Smal_2744 Smal_2744 pnp pnp nadD nadD Smal_2910 Smal_2910 Smal_2916 Smal_2916 Smal_2972 Smal_2972 Smal_2991 Smal_2991 Smal_2995 Smal_2995 Smal_3034 Smal_3034 aroK aroK Smal_3042 Smal_3042 Smal_3085 Smal_3085 Smal_3143 Smal_3143 Smal_3165 Smal_3165 coaE coaE Smal_3180 Smal_3180 Smal_3214 Smal_3214 pgk pgk rpoZ rpoZ gmk gmk selD selD Smal_3269 Smal_3269 rph rph Smal_3285 Smal_3285 Smal_3298 Smal_3298 adk adk pfp pfp Smal_3355 Smal_3355 Smal_3358 Smal_3358 Smal_3384 Smal_3384 cca cca Smal_3425 Smal_3425 Smal_3431 Smal_3431 Smal_3433 Smal_3433 Smal_3435 Smal_3435 Smal_3455 Smal_3455 Smal_3456 Smal_3456 Smal_3506 Smal_3506 glmU glmU glpK glpK Smal_3532 Smal_3532 Smal_3578 Smal_3578 tsaC tsaC Smal_3619 Smal_3619 Smal_3655 Smal_3655 Smal_3660 Smal_3660 Smal_3671 Smal_3671 Smal_3677 Smal_3677 aceK aceK Smal_3705 Smal_3705 Smal_3706 Smal_3706 Smal_3723 Smal_3723 Smal_3754 Smal_3754 Smal_3756 Smal_3756 Smal_3757 Smal_3757 Smal_3766 Smal_3766 Smal_3771 Smal_3771 Smal_3816 Smal_3816 Smal_3839 Smal_3839 Smal_3875 Smal_3875 polA polA Smal_3949 Smal_3949 Smal_3952 Smal_3952 Smal_3968 Smal_3968 Smal_3978 Smal_3978 Smal_4000 Smal_4000
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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Smal_0002DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (366 aa)
Smal_0012Phospholipase D/Transphosphatidylase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. (486 aa)
Smal_0026TIGRFAM: DNA ligase D; DNA ligase D, 3'-phosphoesterase domain protein; DNA polymerase LigD, polymerase domain protein; DNA polymerase LigD, ligase domain protein; PFAM: DNA primase small subunit; ATP dependent DNA ligase domain protein; ATP dependent DNA ligase; KEGG: xcb:XC_1808 ATP-dependent DNA ligase. (825 aa)
tdkPFAM: thymidine kinase; KEGG: xac:XAC4282 thymidine kinase. (206 aa)
Smal_0062Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; KEGG: reu:Reut_B4471 PAS/PAC sensor hybrid histidine kinase. (807 aa)
Smal_0106PFAM: PEBP family protein; KEGG: xcb:XC_0191 hypothetical protein. (203 aa)
Smal_0117C-terminal ATPase domain signal transduction-like protein; KEGG: fjo:Fjoh_4494 hypothetical protein. (569 aa)
Smal_0122Signal transduction histidine kinase, nitrogen specific, NtrB; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: xcb:XC_0197 two-component system sensor protein. (353 aa)
Smal_0151PFAM: aminoglycoside phosphotransferase; KEGG: xac:XAC3528 hypothetical protein. (374 aa)
Smal_0156Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; PAS fold-3 domain protein; SMART: extracellular solute-binding protein family 3; KEGG: pen:PSEEN3768 two-component sensor/response regulator protein. (1199 aa)
Smal_01752-polyprenylphenol 6-hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfamily. (551 aa)
Smal_0190Cyclic nucleotide-binding protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; cyclic nucleotide-binding; KEGG: xcv:XCV0266 putative cyclic nucleotide-binding protein. (346 aa)
Smal_0230Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: xac:XAC4022 two-component system sensor protein. (475 aa)
coaXPutative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. (243 aa)
Smal_0257Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: xcv:XCV4087 two-component system sensor kinase. (404 aa)
Smal_0288PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; Osmosensitive K channel His kinase sensor; UspA domain protein; KEGG: xcb:XC_3529 two-component system sensor protein. (891 aa)
anmKProtein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (378 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (579 aa)
glnE(Glutamate--ammonia-ligase) adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal tra [...] (931 aa)
Smal_0380KEGG: xcc:XCC1902 hypothetical protein. (308 aa)
Smal_0384KEGG: xcb:XC_3104 hypothetical protein. (355 aa)
Smal_0420Signal transduction histidine kinase, LytS; PFAM: ATP-binding region ATPase domain protein; histidine kinase internal region; KEGG: xcv:XCV3840 putative two-component system sensor kinase. (419 aa)
Smal_0447KEGG: xcv:XCV3804 two-component system sensor histidine kinase-response regulator hybrid protein; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein. (662 aa)
dinBDNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (356 aa)
Smal_0471Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: bac:BamMC406_5549 integral membrane sensor signal transduction histidine kinase. (489 aa)
Smal_0472Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: cvi:CV_0760 probable two-component sensor protein. (448 aa)
Smal_0504Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (295 aa)
Smal_0508KEGG: xcb:XC_3609 phosphomannose isomerase/GDP-mannose pyrophosphorylase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl transferase; Cupin 2 conserved barrel domain protein. (467 aa)
Smal_0529TIGRFAM: CDP-diacylglycerol/serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; KEGG: xac:XAC3565 phosphatidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (258 aa)
Smal_0535PFAM: DNA polymerase III chi subunit HolC; KEGG: xcb:XC_3586 DNA polymerase III subunit chi. (141 aa)
thiLThiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (320 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (361 aa)
Smal_0616Signal transduction histidine kinase, LytS; PFAM: histidine kinase internal region; KEGG: sru:SRU_0415 putative transmembrane sensor histidine kinase transcription regulator protein. (349 aa)
Smal_0619Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: sse:Ssed_2720 sensor histidine kinase. (430 aa)
rbsKRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (321 aa)
Smal_0653Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: xcb:XC_3451 two-component system sensor protein. (423 aa)
Smal_0655Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. (131 aa)
Smal_0718PFAM: protein of unknown function DUF344; KEGG: xcb:XC_3366 transcriptional regulator. (260 aa)
ispE4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (289 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (319 aa)
Smal_0737PFAM: EAL domain protein; response regulator receiver; KEGG: pfo:PflO1_3039 putative diguanylate phosphodiesterase (EAL domain) with response regulator receiver modulation. (406 aa)
Smal_0738Integral membrane sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: pap:PSPA7_3015 kinase sensor protein. (925 aa)
rpoBDNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1384 aa)
rpoCDNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1407 aa)
rpoADNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (332 aa)
Smal_0798PFAM: protein of unknown function DUF161; KEGG: cmi:CMM_0762 hypothetical protein. (213 aa)
ppkPolyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (695 aa)
Smal_0823PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: phosphate regulon sensor kinase PhoR; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: xcb:XC_3273 two-component system sensor protein. (443 aa)
dnaQDNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. (243 aa)
kdkALipopolysaccharide kinase; Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D- manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position; Belongs to the protein kinase superfamily. KdkA/RfaP family. (249 aa)
dnaXDNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (681 aa)
Smal_0870Mn2+-dependent serine/threonine protein kinase; KEGG: ngo:NGO0688 hypothetical protein. (260 aa)
tmkdTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (221 aa)
Smal_0878KEGG: xcv:XCV1151 DNA polymerase III subunit delta'. (318 aa)
Smal_0900KEGG: pna:Pnap_2274 hypothetical protein. (212 aa)
Smal_0918Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: pfl:PFL_2572 sensor histidine kinase. (461 aa)
Smal_0947Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (589 aa)
Smal_0949PFAM: PTS system fructose subfamily IIA component; KEGG: xom:XOO_1177 hypothetical protein. (130 aa)
hprKHPr kinase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). (316 aa)
Smal_0952Putative PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: xcv:XCV3120 putative nitrogen regulatory IIA protein (protein-N(pi)-phosphohistidine-sugar phosphotransferase). (150 aa)
Smal_0954RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (474 aa)
Smal_0975PFAM: Nucleotidyl transferase; KEGG: xcv:XCV3100 putative nucleotidyltransferase. (236 aa)
Smal_1011TIGRFAM: aspartate kinase; diaminopimelate decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2; aspartate/glutamate/uridylate kinase; KEGG: xcb:XC_1372 bifunctional aspartate kinase/diaminopimelate decarboxylase protein; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (864 aa)
Smal_1030Non-specific serine/threonine protein kinase; KEGG: xcb:XC_2577 hypothetical protein; PFAM: KaiA binding; SMART: AAA ATPase. (498 aa)
Smal_1031KEGG: xcv:XCV1708 histidine kinase-response regulator hybrid protein; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. (689 aa)
Smal_1051TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: ent:Ent638_2010 diguanylate cyclase. (350 aa)
Smal_1056TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: reh:H16_B1591 putative GGDEF family protein. (580 aa)
mdcBtriphosphoribosyl-dephospho-CoA synthase MdcB; Involved in the formation of 2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase; Belongs to the CitG/MdcB family. (285 aa)
Smal_1077TIGRFAM: holo-ACP synthase, malonate decarboxylase-specific; KEGG: xcv:XCV0598 phosphoribosyl-dephospho-CoA transferase. (213 aa)
Smal_1098Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: xcb:XC_3118 two-component system sensor protein. (398 aa)
Smal_1124Riboflavin biosynthesis protein RibF; KEGG: xcb:XC_3088 bifunctional riboflavin kinase/FMN adenylyltransferase; TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; Belongs to the ribF family. (315 aa)
Smal_1189Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; Two-component sensor kinase domain protein; KEGG: mca:MCA1765 sensor histidine kinase. (459 aa)
Smal_1194TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: psa:PST_0006 GGDEF domain protein. (471 aa)
Smal_1205Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: xcc:XCC2694 sensory histidine kinase CreC. (486 aa)
Smal_1226Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); KEGG: xcv:XCV2973 putative signal transduction protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein. (807 aa)
Smal_1227TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: mms:mma_1623 diguanylate cyclase. (554 aa)
Smal_1229TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein; KEGG: xcv:XCV2971 putative sensor protein. (356 aa)
Smal_1245KEGG: xcv:XCV1456 hypothetical protein. (329 aa)
Smal_1251KEGG: xcb:XC_2880 DNA polymerase III subunit alpha; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; DNA polymerase III alpha subunit; SMART: phosphoesterase PHP domain protein. (1196 aa)
Smal_1260PFAM: phosphatidate cytidylyltransferase; KEGG: xac:XAC1416 phosphatidate cytidylyltransferase; Belongs to the CDS family. (278 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (242 aa)
Smal_1264TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; Metal-dependent hydrolase HDOD; KEGG: xac:XAC1420 hypothetical protein. (512 aa)
glnDUTP-GlnB uridylyltransferase, GlnD; KEGG: xcv:XCV1486 PII uridylyl-transferase; TIGRFAM: protein-P-II uridylyltransferase; PFAM: amino acid-binding ACT domain protein; DNA polymerase beta domain protein region; metal-dependent phosphohydrolase HD sub domain; GlnD PII-uridylyltransferase; SMART: metal-dependent phosphohydrolase HD region. (875 aa)
Smal_1300Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: mes:Meso_2910 periplasmic sensor signal transduction histidine kinase. (469 aa)
Smal_1301TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; Two component regulator propeller; Two component regulator three Y domain protein; KEGG: xcv:XCV1610 putative sensor protein. (1008 aa)
Smal_1334TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver; KEGG: xcv:XCV2660 two-component system response regulator. (447 aa)
Smal_1335PFAM: MASE1 domain protein; KEGG: xcb:XC_2013 sensor kinase. (536 aa)
Smal_1337PFAM: MASE1 domain protein; KEGG: xcv:XCV1810 putative sugar transporter component. (532 aa)
Smal_1366KEGG: xcb:XC_1798 hypothetical protein. (116 aa)
Smal_1369PFAM: protein of unknown function DUF343; KEGG: xac:XAC2680 hypothetical protein. (89 aa)
Smal_1394Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: bja:blr4803 two-component hybrid sensor and regulator. (447 aa)
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (339 aa)
kdsB3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (257 aa)
Smal_1404KEGG: xcc:XCC2114 CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (208 aa)
ispD2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (232 aa)
Smal_1474TIGRFAM: 2-polyprenylphenol 6-hydroxylase; PFAM: ABC-1 domain protein; KEGG: xcb:XC_2511 ubiquinone biosynthesis protein. (561 aa)
Smal_1505TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: xcb:XC_2499 phosphomethylpyrimidine kinase. (269 aa)
pcnBpoly(A) polymerase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (461 aa)
Smal_1516KEGG: xcb:XC_2469 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK. (161 aa)
Smal_1523Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: xcb:XC_2456 two-component system sensor protein. (408 aa)
glkGlucokinase; KEGG: xom:XOO_2192 glucokinase; TIGRFAM: glucokinase; PFAM: Glucokinase; Belongs to the bacterial glucokinase family. (335 aa)
coaDPantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (169 aa)
Smal_1604TIGRFAM: pyridoxal kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: xcv:XCV1566 pyridoxine kinase. (302 aa)
Smal_1611Diguanylate cyclase/phosphodiesterase with GAF sensor; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein; KEGG: cps:CPS_4411 GAF domain/GGDEF domain/EAL domain protein. (946 aa)
selOProtein of unknown function UPF0061; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). Belongs to the SELO family. (521 aa)
cmkKEGG: xcv:XCV2497 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region. (225 aa)
Smal_1650PFAM: glycosyl transferase family 4; KEGG: xcc:XCC2190 lipopolysaccharide core biosynthesis protein. (329 aa)
Smal_1652TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase; KEGG: xcv:XCV2490 UTP-glucose-1-phosphate uridylyltransferase. (292 aa)
ndkNucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (141 aa)
Smal_1717PFAM: aminoglycoside phosphotransferase; KEGG: ret:RHE_CH02947 putative aminoglycoside 3'-phosphotransferase protein; Belongs to the aminoglycoside phosphotransferase family. (267 aa)
Smal_1721PFAM: aminoglycoside phosphotransferase; KEGG: lpn:lpg1492 spectinomycin phosphotransferase. (335 aa)
Smal_1735PFAM: response regulator receiver; KEGG: xac:XAC1284 two-component system regulatory protein. (119 aa)
Smal_1736PAS/PAC sensor signal transduction histidine kinase; KEGG: xac:XAC1282 two-component system sensor protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. (387 aa)
Smal_1737Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: xcb:XC_3057 two-component system sensor protein. (1037 aa)
Smal_1740PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: xcb:XC_3060 two-component system regulatory protein. (377 aa)
Smal_1749Aspartate kinase; KEGG: xcv:XCV1866 bifunctional aspartokinase/homoserine dehydrogenase I; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; In the C-terminal section; belongs to the homoserine dehydrogenase family. (834 aa)
thrBGHMP kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (304 aa)
Smal_1766PFAM: Glucokinase; KEGG: xac:XAC3070 glucokinase; Belongs to the bacterial glucokinase family. (340 aa)
Smal_1777PFAM: PfkB domain protein; KEGG: xcb:XC_2727 fructokinase. (331 aa)
Smal_1791Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: aav:Aave_2525 integral membrane sensor signal transduction histidine kinase. (358 aa)
Smal_1852CheA signal transduction histidine kinase; PFAM: CheW domain protein; ATP-binding region ATPase domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; KEGG: xcb:XC_2303 chemotaxis protein. (664 aa)
Smal_1859CheA signal transduction histidine kinase; PFAM: CheW domain protein; ATP-binding region ATPase domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; KEGG: xom:XOO_2483 chemotaxis related protein. (614 aa)
fliARNA polymerase, sigma 28 subunit, FliA/WhiG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily. (247 aa)
Smal_1885RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (469 aa)
Smal_1911Histidine kinase; PFAM: ATP-binding region ATPase domain protein; KEGG: xom:XOO_2423 histidine kinase. (406 aa)
Smal_1912Cyclic nucleotide-binding protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; response regulator receiver; KEGG: xom:XOO_2422 C-di-GMP phosphodiesterase A. (590 aa)
Smal_1914Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); KEGG: xcv:XCV2041 putative signal transduction protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; SMART: PAC repeat-containing protein. (919 aa)
Smal_1923PFAM: aminoglycoside/hydroxyurea antibiotic resistance kinase; KEGG: spe:Spro_2227 aminoglycoside/hydroxyurea antibiotic resistance kinase. (270 aa)
Smal_1948Histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: cvi:CV_2400 sensor protein EvgS precursor. (727 aa)
Smal_1989KEGG: xcb:XC_1389 hypothetical protein. (208 aa)
Smal_2030TIGRFAM: phosphocarrier, HPr family; phosphoenolpyruvate-protein phosphotransferase; PFAM: phosphocarrier HPr protein; PEP-utilizing protein; phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; PEP-utilising protein mobile region; PEP-utilising protein domain protein; KEGG: xac:XAC2501 multiphosphoryl transfer protein. (836 aa)
Smal_2031KEGG: xac:XAC2502 1-phosphofructokinase (fructose 1-phosphate kinase); TIGRFAM: 1-phosphofructokinase; PFAM: PfkB domain protein; Belongs to the carbohydrate kinase PfkB family. (318 aa)
Smal_2032TIGRFAM: PTS system, fructose-specific, IIB subunnit; PTS system, fructose subfamily, IIC subunit; PFAM: phosphotransferase system EIIC; phosphotransferase system PTS fructose-specific IIB subunit; KEGG: xom:XOO_2652 PTS system fructose-specific IIBC component. (568 aa)
Smal_2060Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; KEGG: pae:PA3271 probable two-component sensor. (1111 aa)
Smal_2114Diguanylate cyclase with PAS/PAC sensor; KEGG: xcc:XCC4224 hypothetical protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; SMART: PAS domain containing protein. (569 aa)
Smal_2119Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: bur:Bcep18194_C6826 periplasmic sensor signal transduction histidine kinase. (358 aa)
Smal_2130Serine/threonine protein kinase; PFAM: Lanthionine synthetase C family protein; SMART: serine/threonine protein kinase; KEGG: sen:SACE_4025 membrane translocator. (894 aa)
Smal_2138Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: bbr:BB1101 two component sensor kinase. (351 aa)
Smal_2166Heavy metal sensor signal transduction histidine kinase; Member of a two-component regulatory system. (455 aa)
Smal_2173Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; Two-component sensor kinase domain protein; KEGG: mca:MCA1765 sensor histidine kinase. (457 aa)
Smal_2180KEGG: xcv:XCV1821 hypothetical protein. (208 aa)
Smal_2182KEGG: mrd:Mrad2831_4235 signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: HWE histidine kinase; PAS fold-4 domain protein; SMART: PAC repeat-containing protein. (528 aa)
Smal_2224Putative PAS/PAC sensor protein; KEGG: wsu:WS1556 diguanylate cyclase; TIGRFAM: PAS sensor protein; PFAM: PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. (142 aa)
Smal_2239Molybdopterin guanine dinucleotide synthase; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (182 aa)
Smal_2262Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. (130 aa)
Smal_2275PFAM: AMP-dependent synthetase and ligase; KEGG: mxa:MXAN_3645 2,3-dihydroxybenzoate-AMP ligase. (550 aa)
Smal_2339Histidine kinase; PFAM: ATP-binding region ATPase domain protein; Two component regulator propeller; Two component regulator three Y domain protein; histidine kinase dimerisation and phosphoacceptor region; KEGG: xcb:XC_1939 two-component system sensor protein. (1009 aa)
Smal_2343PFAM: histidine kinase internal region; KEGG: cvi:CV_0103 probable two-component system sensor protein. (361 aa)
Smal_2379KEGG: pmy:Pmen_1935 nucleotidyltransferase/DNA polymerase involved in DNA repair-like protein. (469 aa)
dnaE2DNA polymerase III, alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1036 aa)
Smal_2404TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: tbd:Tbd_2634 diguanylate cyclase with PAS/PAC sensor. (479 aa)
Smal_2409Diguanylate cyclase with PAS/PAC sensor; KEGG: xcv:XCV0667 putative sensor protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein. (729 aa)
Smal_2413Phage shock protein C, PspC; PFAM: PspC domain protein; KEGG: xom:XOO_2087 hypothetical protein. (67 aa)
Smal_2417TIGRFAM: CDP-diacylglycerol/serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; KEGG: xcv:XCV2207 CDP-diacylglycerol--serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (204 aa)
Smal_2421Protein of unknown function DUF299; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation. (273 aa)
Smal_2422Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (792 aa)
Smal_2464Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: atc:AGR_L_2107 hypothetical protein. (449 aa)
Smal_2571KEGG: gvi:gll2767 hypothetical protein. (258 aa)
nadKNAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (257 aa)
slyXPFAM: SlyX family protein; KEGG: xom:XOO_1947 hypothetical protein; Belongs to the SlyX family. (79 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (385 aa)
Smal_2726KEGG: xac:XAC2348 acetylglutamate kinase; TIGRFAM: acetylglutamate kinase; PFAM: aspartate/glutamate/uridylate kinase; protein of unknown function DUF619. (442 aa)
Smal_2744TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase HAMP region domain protein; KEGG: xac:XAC2382 GGDEF family protein. (708 aa)
pnpPolyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (702 aa)
nadDNicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (221 aa)
Smal_2910TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta; KEGG: xom:XOO_3140 DNA polymerase III subunit delta. (345 aa)
Smal_2916TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; CHASE2 domain protein; KEGG: cvi:CV_3192 probable two component sensor. (543 aa)
Smal_2972PFAM: response regulator receiver; Hpt domain protein; KEGG: xcb:XC_2965 hypothetical protein. (242 aa)
Smal_2991Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: xcv:XCV1254 two-component system sensor protein. (429 aa)
Smal_2995PFAM: sulfatase; protein of unknown function DUF1705; KEGG: xac:XAC1218 inner membrane protein. (549 aa)
Smal_3034KEGG: ccr:CC_2910 hypothetical protein. (269 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (180 aa)
Smal_3042Integral membrane sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Two component regulator propeller; Two component regulator three Y domain protein; KEGG: xcv:XCV3167 two-component system sensor histidine kinase-response regulator hybrid protein. (1181 aa)
Smal_3085CheA signal transduction histidine kinase; PFAM: response regulator receiver; CheW domain protein; ATP-binding region ATPase domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; KEGG: xcc:XCC2921 PilL protein. (2212 aa)
Smal_3143Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: pau:PA14_41270 putative two-component sensor. (429 aa)
Smal_3165Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: xac:XAC3237 two-component system sensor protein. (592 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (203 aa)
Smal_3180Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: xcv:XCV3364 two-component system sensor protein. (455 aa)
Smal_3214KEGG: xcv:XCV3463 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. (488 aa)
pgkPFAM: phosphoglycerate kinase; KEGG: xcb:XC_0976 phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (391 aa)
rpoZDNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (99 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (221 aa)
selDSelenide, water dikinase; Synthesizes selenophosphate from selenide and ATP. (359 aa)
Smal_3269PFAM: YicC domain protein; domain of unknown function DUF1732; KEGG: xcb:XC_0959 hypothetical protein. (286 aa)
rphRibonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (241 aa)
Smal_3285KEGG: xcv:XCV3530 hypothetical protein. (281 aa)
Smal_3298KEGG: xcv:XCV3547 serine/threonine protein kinase. (220 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (187 aa)
pfpPhosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (418 aa)
Smal_3355PAS/PAC sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; KEGG: xoo:XOO1115 sensor histidine kinase. (880 aa)
Smal_3358Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; Two-component sensor kinase domain protein; KEGG: xcv:XCV3610 two-component system sensor protein. (463 aa)
Smal_3384TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: mag:amb3602 FOG: GGDEF domain. (481 aa)
ccaPolynucleotide adenylyltransferase/metal dependent phosphohydrolase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. (406 aa)
Smal_3425PFAM: Glucokinase; KEGG: xfa:XF1460 glucokinase; Belongs to the bacterial glucokinase family. (339 aa)
Smal_3431TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; KEGG: xac:XAC0686 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine. (173 aa)
Smal_3433PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: xcb:XC_0730 histidine kinase/response regulator hybrid protein. (503 aa)
Smal_3435Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; CHASE3 domain protein; PAS fold-4 domain protein; KEGG: xcv:XCV0744 two-component system sensor protein. (605 aa)
Smal_3455PFAM: PfkB domain protein; KEGG: xcv:XCV0716 putative carbohydrate kinase. (312 aa)
Smal_3456PFAM: sulfatase; KEGG: aha:AHA_0492 sulfatase. (657 aa)
Smal_3506Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; KEGG: xcv:XCV3761 two-component system sensor histidine kinase. (450 aa)
glmUUDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (455 aa)
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (499 aa)
Smal_3532PFAM: histidine kinase internal region; KEGG: xcv:XCV0677 two-component system sensor protein. (338 aa)
Smal_3578PFAM: CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase; KEGG: xcb:XC_3813 hypothetical protein. (351 aa)
tsaCSUA5/yciO/yrdC domain; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. (196 aa)
Smal_3619Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: ccr:CC_1181 sensor histidine kinase. (432 aa)
Smal_3655PFAM: phosphatidate cytidylyltransferase; KEGG: xcv:XCV0555 putative phosphatidate cytidiltransferase. (331 aa)
Smal_3660PFAM: CDP-alcohol phosphatidyltransferase; KEGG: xcv:XCV0548 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase. (205 aa)
Smal_3671PFAM: response regulator receiver; KEGG: xcv:XCV3951 two-component system response regulator. (280 aa)
Smal_3677TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: ppg:PputGB1_2050 diguanylate cyclase. (524 aa)
aceK(Isocitrate dehydrogenase (NADP(+))) kinase; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation. (576 aa)
Smal_3705PFAM: GGDEF domain containing protein; EAL domain protein; response regulator receiver; KEGG: xom:XOO_0483 two-component system regulatory protein. (628 aa)
Smal_3706Hpt sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; KEGG: xcb:XC_0495 two-component system sensor protein. (738 aa)
Smal_3723Diacylglycerol kinase catalytic region; Probably phosphorylates lipids; the in vivo substrate is unknown; Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily. (317 aa)
Smal_3754TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: xcb:XC_0420 hypothetical protein. (512 aa)
Smal_3756PFAM: ABC-1 domain protein; KEGG: xcb:XC_0417 ABC transporter substrate binding protein. (563 aa)
Smal_3757Phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase; PFAM: sulfatase; KEGG: xac:XAC0421 phosphoglycerol transferase I. (701 aa)
Smal_3766Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; KEGG: mmr:Mmar10_0937 periplasmic sensor signal transduction histidine kinase. (439 aa)
Smal_3771PFAM: protein of unknown function RIO1; KEGG: xcv:XCV4042 putative kinase. (219 aa)
Smal_3816PFAM: ROK family protein; KEGG: spe:Spro_2576 ROK family protein. (312 aa)
Smal_3839Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: xac:XAC0326 two-component system sensor protein. (463 aa)
Smal_3875TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: ajs:Ajs_4122 diguanylate cyclase. (400 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (924 aa)
Smal_3949PFAM: phospholipase D/Transphosphatidylase; KEGG: xcb:XC_4117 cardiolipin synthase; Belongs to the phospholipase D family. Cardiolipin synthase subfamily. (472 aa)
Smal_3952KEGG: lpc:LPC_0800 DNA polymerase III, epsilon subunit; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease. (169 aa)
Smal_3968PFAM: 4'-phosphopantetheinyl transferase; KEGG: xac:XAC4168 HetI protein; Belongs to the P-Pant transferase superfamily. (199 aa)
Smal_3978Multi-sensor hybrid histidine kinase; KEGG: xom:XOO_0308 two-component system sensor protein; TIGRFAM: PAS sensor protein; PFAM: Na+/solute symporter; response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: PAS domain containing protein. (1152 aa)
Smal_4000TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: pmy:Pmen_4080 diguanylate cyclase. (426 aa)
Your Current Organism:
Stenotrophomonas maltophilia R5513
NCBI taxonomy Id: 391008
Other names: S. maltophilia R551-3, Stenotrophomonas maltophilia R551-3, Stenotrophomonas maltophilia str. R551-3, Stenotrophomonas maltophilia strain R551-3
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