node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EHF_0011 | EHF_0531 | EHF_0011 | EHF_0531 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein. | Coproporphyrinogen III oxidase family protein; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.428 |
EHF_0011 | EHF_0762 | EHF_0011 | EHF_0762 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein. | Ubiquinone biosynthesis COQ7 family protein; Belongs to the COQ7 family. | 0.610 |
EHF_0011 | EHF_0841 | EHF_0011 | EHF_0841 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein. | COQ9 family protein. | 0.640 |
EHF_0011 | ubiA | EHF_0011 | EHF_0385 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein. | 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.624 |
EHF_0011 | ubiB | EHF_0011 | EHF_0736 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein. | 2-polyprenylphenol 6-hydroxylase. | 0.710 |
EHF_0011 | ubiG | EHF_0011 | EHF_0566 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein. | 3-demethylubiquinone-9 3-O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.984 |
EHF_0386 | ubiA | EHF_0386 | EHF_0385 | Flavin reductase like domain protein. | 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.695 |
EHF_0415 | EHF_0416 | EHF_0415 | EHF_0416 | Hypothetical protein. | Polyketide cyclase / dehydrase and lipid transport family protein. | 0.488 |
EHF_0416 | EHF_0415 | EHF_0416 | EHF_0415 | Polyketide cyclase / dehydrase and lipid transport family protein. | Hypothetical protein. | 0.488 |
EHF_0416 | ubiA | EHF_0416 | EHF_0385 | Polyketide cyclase / dehydrase and lipid transport family protein. | 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.412 |
EHF_0416 | ubiB | EHF_0416 | EHF_0736 | Polyketide cyclase / dehydrase and lipid transport family protein. | 2-polyprenylphenol 6-hydroxylase. | 0.445 |
EHF_0416 | ubiG | EHF_0416 | EHF_0566 | Polyketide cyclase / dehydrase and lipid transport family protein. | 3-demethylubiquinone-9 3-O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.475 |
EHF_0424 | EHF_0531 | EHF_0424 | EHF_0531 | uroporphyrinogen-III synthase HemD family protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Coproporphyrinogen III oxidase family protein; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.423 |
EHF_0424 | EHF_0622 | EHF_0424 | EHF_0622 | uroporphyrinogen-III synthase HemD family protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.977 |
EHF_0424 | hemB | EHF_0424 | EHF_0720 | uroporphyrinogen-III synthase HemD family protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.859 |
EHF_0424 | hemC | EHF_0424 | EHF_0624 | uroporphyrinogen-III synthase HemD family protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.977 |
EHF_0424 | hemH | EHF_0424 | EHF_0344 | uroporphyrinogen-III synthase HemD family protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.465 |
EHF_0531 | EHF_0011 | EHF_0531 | EHF_0011 | Coproporphyrinogen III oxidase family protein; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein. | 0.428 |
EHF_0531 | EHF_0424 | EHF_0531 | EHF_0424 | Coproporphyrinogen III oxidase family protein; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | uroporphyrinogen-III synthase HemD family protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.423 |
EHF_0531 | EHF_0915 | EHF_0531 | EHF_0915 | Coproporphyrinogen III oxidase family protein; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | Hypothetical protein. | 0.942 |