STRINGSTRING
EHF_0058 EHF_0058 EHF_0056 EHF_0056 EHF_0055 EHF_0055 EHF_0054 EHF_0054 EHF_0053 EHF_0053 EHF_0052 EHF_0052 EHF_0051 EHF_0051 EHF_0050 EHF_0050 EHF_0048 EHF_0048 EHF_0047 EHF_0047 EHF_0045 EHF_0045 EHF_0044 EHF_0044 EHF_0042 EHF_0042 EHF_0040 EHF_0040 EHF_0039 EHF_0039 secA secA EHF_0002 EHF_0002 EHF_0992 EHF_0992 EHF_0990 EHF_0990 EHF_0988 EHF_0988 EHF_0972 EHF_0972 EHF_0970 EHF_0970 secF secF gshA gshA atpH atpH atpA atpA EHF_0924 EHF_0924 EHF_0917 EHF_0917 EHF_0891 EHF_0891 EHF_0881 EHF_0881 EHF_0875 EHF_0875 EHF_0869 EHF_0869 pstC pstC EHF_0843 EHF_0843 secE secE EHF_0819 EHF_0819 EHF_0796 EHF_0796 EHF_0741 EHF_0741 tatA tatA znuC znuC EHF_0735 EHF_0735 EHF_0718 EHF_0718 EHF_0717 EHF_0717 nuoC nuoC nuoB nuoB nuoA nuoA agcS agcS atpG atpG EHF_0574 EHF_0574 nuoG nuoG nuoD nuoD EHF_0532 EHF_0532 EHF_0526 EHF_0526 EHF_0524 EHF_0524 atpD atpD mgtE mgtE EHF_0509 EHF_0509 tatC tatC nuoN nuoN EHF_0503 EHF_0503 EHF_0502 EHF_0502 EHF_0500 EHF_0500 nuoF nuoF EHF_0470 EHF_0470 EHF_0469 EHF_0469 petB petB petA petA EHF_0460 EHF_0460 EHF_0454 EHF_0454 EHF_0445 EHF_0445 EHF_0444 EHF_0444 EHF_0443 EHF_0443 EHF_0442 EHF_0442 EHF_0441 EHF_0441 EHF_0440 EHF_0440 EHF_0436 EHF_0436 EHF_0418 EHF_0418 EHF_0412 EHF_0412 EHF_0411 EHF_0411 EHF_0409 EHF_0409 EHF_0408 EHF_0408 pstB pstB EHF_0383 EHF_0383 secY secY EHF_0335 EHF_0335 EHF_0302 EHF_0302 EHF_0284 EHF_0284 ccmC ccmC EHF_0274 EHF_0274 EHF_0269 EHF_0269 ccmA ccmA EHF_0204 EHF_0204 EHF_0187 EHF_0187 coxB coxB ctaD ctaD EHF_0151 EHF_0151 EHF_0098 EHF_0098 EHF_0096 EHF_0096 atpB atpB EHF_0093 EHF_0093 EHF_0092 EHF_0092 EHF_0089 EHF_0089 secD secD EHF_0066 EHF_0066 EHF_0064 EHF_0064 EHF_0061 EHF_0061 EHF_0060 EHF_0060 EHF_0057 EHF_0057
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EHF_0058Surface antigen family protein. (286 aa)
EHF_0056Outer membrane beta-barrel domain protein. (281 aa)
EHF_0055Surface antigen family protein. (296 aa)
EHF_0054Surface antigen family protein. (293 aa)
EHF_0053Surface antigen family protein. (296 aa)
EHF_0052Surface antigen family protein. (301 aa)
EHF_0051Surface antigen family protein. (283 aa)
EHF_0050Surface antigen family protein. (278 aa)
EHF_0048Surface antigen family protein. (278 aa)
EHF_0047Surface antigen family protein. (278 aa)
EHF_0045Surface antigen family protein. (279 aa)
EHF_0044Surface antigen family protein. (278 aa)
EHF_0042Surface antigen family protein. (278 aa)
EHF_0040Surface antigen family protein. (276 aa)
EHF_0039Surface antigen family protein. (271 aa)
secAPreprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. (862 aa)
EHF_0002Cytochrome c oxidase subunit 3. (274 aa)
EHF_0992Type IV secretory system Conjugative DNA transfer family protein. (677 aa)
EHF_0990Bacterial conjugation TrbI-like family protein. (436 aa)
EHF_0988virB8 family protein. (234 aa)
EHF_0972ccmB family protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. (220 aa)
EHF_0970Cation diffusion facilitator transporter family protein. (306 aa)
secFProtein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (293 aa)
gshAGlutamate--cysteine ligase. (400 aa)
atpHATP synthase F1, delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (187 aa)
atpAATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (508 aa)
EHF_0924Cytochrome C assembly family protein. (635 aa)
EHF_0917Sodium/hydrogen exchanger family protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (568 aa)
EHF_0891Preprotein translocase SecG subunit. (70 aa)
EHF_0881NADH-Ubiquinone/plastoquinone (complex I), various chains family protein. (491 aa)
EHF_0875Hypothetical protein. (761 aa)
EHF_0869Sugar (and other) transporter family protein. (422 aa)
pstCPhosphate ABC transporter, permease protein PstC; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (292 aa)
EHF_0843Binding--dependent transport system inner membrane component family protein. (521 aa)
secEPreprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. (65 aa)
EHF_0819na+/H+ ion antiporter subunit. (156 aa)
EHF_0796Hypothetical protein. (347 aa)
EHF_0741ABC transporter family protein; Belongs to the ABC transporter superfamily. (340 aa)
tatATwin arginine-targeting translocase, TatA/E family protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (56 aa)
znuCABC transporter family protein; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family. (242 aa)
EHF_0735Major Facilitator Superfamily protein. (401 aa)
EHF_0718Sugar (and other) transporter family protein. (412 aa)
EHF_0717Sugar (and other) transporter family protein. (411 aa)
nuoCNADH-quinone oxidoreductase, subunit C; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family. (192 aa)
nuoBNADH-quinone oxidoreductase, B subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (177 aa)
nuoANADH-ubiquinone/plastoquinone oxidoreductase, chain 3 family protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family. (123 aa)
agcSAmino acid carrier family protein. (460 aa)
atpGATP synthase F1, gamma subunit. (256 aa)
EHF_0574TRAP transporter solute receptor, TAXI family protein. (328 aa)
nuoGNADH dehydrogenase (quinone), G subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. (684 aa)
nuoDNADH dehydrogenase (quinone), D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family. (384 aa)
EHF_0532Gram-negative porin family protein. (391 aa)
EHF_0526Dicarboxylate symporter family protein; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (389 aa)
EHF_0524virB8 family protein. (148 aa)
atpDATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (480 aa)
mgtEMagnesium transporter; Acts as a magnesium transporter. (456 aa)
EHF_0509acrB/AcrD/AcrF family protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1032 aa)
tatCTwin arginine-targeting protein translocase TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. (249 aa)
nuoNProton-translocating NADH-quinone oxidoreductase, chain N family protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (475 aa)
EHF_0503Proton-translocating NADH-quinone oxidoreductase, chain M family protein. (478 aa)
EHF_0502Proton-translocating NADH-quinone oxidoreductase, chain L family protein. (621 aa)
EHF_0500NADH-ubiquinone/plastoquinone oxidoreductase chain 6 family protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (200 aa)
nuoFNADH oxidoreductase (quinone), F subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family. (420 aa)
EHF_0470Hypothetical protein. (488 aa)
EHF_0469Hypothetical protein. (669 aa)
petBCytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (377 aa)
petAUbiquinol-cytochrome c reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (187 aa)
EHF_0460ABC 3 transport family protein. (267 aa)
EHF_0454Efflux transporter, RND family, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (357 aa)
EHF_0445trbL/VirB6 plasmid conjugal transfer family protein. (1942 aa)
EHF_0444trbL/VirB6 plasmid conjugal transfer family protein. (1409 aa)
EHF_0443trbL/VirB6 plasmid conjugal transfer family protein. (916 aa)
EHF_0442trbL/VirB6 plasmid conjugal transfer family protein. (803 aa)
EHF_0441Type IV secretion/conjugal transfer ATPase, VirB4 family protein. (764 aa)
EHF_0440Type IV secretory pathway, VirB3-like family protein. (97 aa)
EHF_0436Binding--dependent transport system inner membrane component family protein. (106 aa)
EHF_0418NADH-Ubiquinone/plastoquinone (complex I), various chains family protein. (529 aa)
EHF_0412NADH-ubiquinone/plastoquinone oxidoreductase chain 4L family protein. (97 aa)
EHF_0411Na+/H+ antiporter family protein. (139 aa)
EHF_0409na+/H+ antiporter subunit. (99 aa)
EHF_0408Multiple resistance and pH regulation F family protein. (89 aa)
pstBPhosphate ABC transporter, ATP-binding protein; Belongs to the ABC transporter superfamily. (253 aa)
EHF_0383Alanine symporter family protein. (437 aa)
secYPreprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (432 aa)
EHF_0335Type I secretion system ATPase family protein. (587 aa)
EHF_0302Hypothetical protein. (203 aa)
EHF_0284NADH-Ubiquinone/plastoquinone (complex I), various chains family protein. (494 aa)
ccmCHeme exporter CcmC family protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. (206 aa)
EHF_0274Drug resistance transporter, Bcr/CflA subfamily protein. (403 aa)
EHF_0269ABC transporter family protein. (580 aa)
ccmAHeme ABC exporter, ATP-binding protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. (217 aa)
EHF_0204Major Facilitator Superfamily protein. (412 aa)
EHF_0187Membrane transport family protein. (305 aa)
coxBCytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B). (232 aa)
ctaDCytochrome c oxidase, subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (518 aa)
EHF_0151Type I secretion outer membrane, TolC family protein. (424 aa)
EHF_0098Cytochrome C and Quinol oxidase polypeptide I family protein. (333 aa)
EHF_0096Pentapeptide repeats family protein. (616 aa)
atpBATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (243 aa)
EHF_0093ATP synthase subunit C family protein. (73 aa)
EHF_0092ATP synthase B/B' CF family protein; Belongs to the ATPase B chain family. (167 aa)
EHF_0089Cation transport family protein; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family. (485 aa)
secDProtein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (505 aa)
EHF_0066Surface antigen family protein. (274 aa)
EHF_0064Surface antigen family protein. (279 aa)
EHF_0061Surface antigen family protein. (291 aa)
EHF_0060Surface antigen family protein. (278 aa)
EHF_0057Surface antigen family protein. (281 aa)
Your Current Organism:
Ehrlichia sp. HF
NCBI taxonomy Id: 391036
Other names: E. sp. HF
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