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Sare_0054 Sare_0054 Sare_1274 Sare_1274 Sare_1822 Sare_1822 aroC aroC aroK aroK aroB aroB aroQ-2 aroQ-2 Sare_2513 Sare_2513 Sare_3182 Sare_3182 aroA aroA trpA trpA trpB trpB trpC trpC trpE trpE trpD trpD aroA-2 aroA-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Sare_0054TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: stp:Strop_0049 glutamine amidotransferase of anthranilate synthase. (216 aa)
Sare_1274PFAM: UBA/THIF-type NAD/FAD binding protein; Shikimate/quinate 5-dehydrogenase; Shikimate dehydrogenase substrate binding domain protein; KEGG: fal:FRAAL0918 aminoquinate/shkimate dehydrogenase. (270 aa)
Sare_1822TIGRFAM: shikimate-5-dehydrogenase; PFAM: Shikimate/quinate 5-dehydrogenase; Shikimate dehydrogenase substrate binding domain protein; KEGG: stp:Strop_1831 shikimate-5-dehydrogenase; Belongs to the shikimate dehydrogenase family. (275 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (402 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (167 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (357 aa)
aroQ-23-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (143 aa)
Sare_2513PFAM: Chorismate binding-like; KEGG: stp:Strop_2375 anthranilate synthase component I and chorismate binding protein. (408 aa)
Sare_3182PFAM: glutamine amidotransferase class-I; Chorismate binding-like; KEGG: stp:Strop_2960 glutamine amidotransferase class-I. (651 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (414 aa)
trpATryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (267 aa)
trpBTryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (410 aa)
trpCPFAM: Indole-3-glycerol phosphate synthase; KEGG: stp:Strop_3172 indole-3-glycerol-phosphate synthase; Belongs to the TrpC family. (267 aa)
trpEAnthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (517 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (353 aa)
aroA-23-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (433 aa)
Your Current Organism:
Salinispora arenicola
NCBI taxonomy Id: 391037
Other names: S. arenicola CNS-205, Salinispora arenicola CNS-205, Salinispora arenicola str. CNS-205, Salinispora arenicola strain CNS-205
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