STRINGSTRING
Sare_2709 Sare_2709 Sare_5105 Sare_5105 Sare_5064 Sare_5064 Sare_5051 Sare_5051 Sare_4904 Sare_4904 Sare_4903 Sare_4903 Sare_4880 Sare_4880 Sare_4866 Sare_4866 Sare_4841 Sare_4841 Sare_4794 Sare_4794 Sare_4793 Sare_4793 ftsH ftsH Sare_4740 Sare_4740 Sare_4709 Sare_4709 Sare_4579 Sare_4579 Sare_4482 Sare_4482 Sare_4469 Sare_4469 Sare_4342 Sare_4342 fusA fusA tuf tuf Sare_4207 Sare_4207 ychF ychF Sare_4120 Sare_4120 rsgA-2 rsgA-2 Sare_3990 Sare_3990 clpX clpX obg obg lepA lepA era era Sare_3630 Sare_3630 Sare_3458 Sare_3458 ftsZ ftsZ Sare_3425 Sare_3425 uvrB uvrB Sare_3360 Sare_3360 rsgA rsgA uvrA uvrA Sare_1918 Sare_1918 Sare_1835 Sare_1835 Sare_1815 Sare_1815 ruvB ruvB ruvA ruvA Sare_1772 Sare_1772 Sare_1552 Sare_1552 Sare_1531 Sare_1531 Sare_1448 Sare_1448 hflX hflX infB infB Sare_1294 Sare_1294 ffh ffh ftsY ftsY smc smc Sare_1169 Sare_1169 Sare_1135 Sare_1135 Sare_1105 Sare_1105 Sare_0995 Sare_0995 Sare_0887 Sare_0887 Sare_0877 Sare_0877 Sare_0845 Sare_0845 Sare_0738 Sare_0738 Sare_0662 Sare_0662 Sare_0536 Sare_0536 Sare_0293 Sare_0293 Sare_0137 Sare_0137 clpB clpB Sare_0021 Sare_0021 Sare_3304 Sare_3304 Sare_3254 Sare_3254 Sare_3112 Sare_3112 Sare_3085 Sare_3085 Sare_2927 Sare_2927 Sare_2847 Sare_2847 htpG htpG Sare_2478 Sare_2478 Sare_2464 Sare_2464 arc arc Sare_2308 Sare_2308 lon lon Sare_2192 Sare_2192 Sare_1939 Sare_1939 Sare_1924 Sare_1924
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Sare_2709KEGG: stp:Strop_2527 magnesium chelatase; PFAM: magnesium chelatase ChlI subunit; von Willebrand factor type A; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase. (730 aa)
Sare_5105PFAM: Cobyrinic acid ac-diamide synthase; KEGG: stp:Strop_4587 cobyrinic acid a,c-diamide synthase. (437 aa)
Sare_5064Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (844 aa)
Sare_5051KEGG: stp:Strop_4541 hypothetical protein. (301 aa)
Sare_4904KEGG: stp:Strop_4429 hypothetical protein. (127 aa)
Sare_4903KEGG: stp:Strop_4428 hypothetical protein. (143 aa)
Sare_4880KEGG: stp:Strop_4394 hypothetical protein. (158 aa)
Sare_4866KEGG: stp:Strop_0101 hypothetical protein. (112 aa)
Sare_4841PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; Parallel beta-helix repeat; KEGG: sen:SACE_5457 putative sporulation protein (partial match). (1105 aa)
Sare_4794KEGG: stp:Strop_4352 hypothetical protein. (383 aa)
Sare_4793PFAM: Anion-transporting ATPase; KEGG: stp:Strop_4351 anion-transporting ATPase. (325 aa)
ftsHATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (669 aa)
Sare_4740KEGG: stp:Strop_4304 hypothetical protein. (186 aa)
Sare_4709PFAM: UvrB/UvrC protein; AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: stp:Strop_4275 ATPase AAA-2 domain protein; Belongs to the ClpA/ClpB family. (844 aa)
Sare_4579TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein; KEGG: sen:SACE_2467 cation-transporting ATPase. (906 aa)
Sare_4482KEGG: stp:Strop_4077 hypothetical protein. (680 aa)
Sare_4469TIGRFAM: phenylacetate-CoA oxygenase, PaaJ subunit; PFAM: protein of unknown function DUF59; KEGG: stp:Strop_4070 phenylacetate-CoA oxygenase, PaaJ subunit. (158 aa)
Sare_4342KEGG: stp:Strop_3957 hypothetical protein. (420 aa)
fusATranslation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] (698 aa)
tufTranslation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (397 aa)
Sare_4207TIGRFAM: ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase; KEGG: stp:Strop_3817 ATP-dependent DNA helicase PcrA. (794 aa)
ychFGTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (361 aa)
Sare_4120PFAM: UvrD/REP helicase; HRDC domain protein; KEGG: stp:Strop_3739 UvrD/REP helicase. (719 aa)
rsgA-2GTPase EngC; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (334 aa)
Sare_3990KEGG: stp:Strop_3609 LAO/AO transport system ATPase; TIGRFAM: LAO/AO transport system ATPase; PFAM: ArgK protein; SMART: AAA ATPase. (329 aa)
clpXATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (429 aa)
obgGTP-binding protein Obg/CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (481 aa)
lepAGTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (640 aa)
eraGTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (300 aa)
Sare_3630KEGG: stp:Strop_3388 hypothetical protein. (705 aa)
Sare_3458PFAM: ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; KEGG: stp:Strop_3232 ATPase associated with various cellular activities, AAA_3. (350 aa)
ftsZCell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (372 aa)
Sare_3425KEGG: stp:Strop_3199 hypothetical protein. (474 aa)
uvrBExcinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (700 aa)
Sare_3360TIGRFAM: small GTP-binding protein; GTP-binding protein TypA; PFAM: elongation factor G domain protein; protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; KEGG: stp:Strop_3132 GTP-binding protein TypA. (622 aa)
rsgARibosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (362 aa)
uvrAExcinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (987 aa)
Sare_1918Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. (191 aa)
Sare_1835PFAM: Clp domain protein. (388 aa)
Sare_1815PFAM: AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: stp:Strop_1824 AAA ATPase, central domain protein. (502 aa)
ruvBHolliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (354 aa)
ruvAHolliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (200 aa)
Sare_1772TIGRFAM: small GTP-binding protein; PFAM: elongation factor G domain protein; protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain IV; KEGG: stp:Strop_1785 small GTP-binding protein. (717 aa)
Sare_1552KEGG: stp:Strop_1592 hypothetical protein. (754 aa)
Sare_1531Heavy metal translocating P-type ATPase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein; KEGG: stp:Strop_1580 heavy metal translocating P-type ATPase. (626 aa)
Sare_1448PFAM: nucleic acid binding OB-fold tRNA/helicase-type; KEGG: stp:Strop_1483 nucleic acid binding, OB-fold, tRNA/helicase-type. (126 aa)
hflXSmall GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. (515 aa)
infBTranslation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (995 aa)
Sare_1294PFAM: Clp domain protein; KEGG: stp:Strop_1344 Clp N terminal domain protein. (243 aa)
ffhSignal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (514 aa)
ftsYSignal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (395 aa)
smcChromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1198 aa)
Sare_1169PFAM: helicase domain protein; nucleic acid binding OB-fold tRNA/helicase-type; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: stp:Strop_1279 DEAD/DEAH box helicase domain protein. (733 aa)
Sare_1135PFAM: ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; KEGG: stp:Strop_1245 ATPase associated with various cellular activities, AAA_3. (369 aa)
Sare_1105TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein; KEGG: stp:Strop_1212 ATPase, P-type (transporting), HAD superfamily, subfamily IC. (902 aa)
Sare_0995Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (204 aa)
Sare_0887KEGG: stp:Strop_0945 hypothetical protein. (268 aa)
Sare_0877KEGG: stp:Strop_0935 hypothetical protein. (202 aa)
Sare_0845PFAM: ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; KEGG: stp:Strop_0902 ATPase associated with various cellular activities, AAA_3. (335 aa)
Sare_0738Sulfate adenylyltransferase, large subunit; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (435 aa)
Sare_0662Protein of unknown function DUF59; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (382 aa)
Sare_0536Heavy metal translocating P-type ATPase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: stp:Strop_0448 heavy metal translocating P-type ATPase. (764 aa)
Sare_0293KEGG: stp:Strop_0254 microtubule-severing ATPase; PFAM: AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; Belongs to the AAA ATPase family. (748 aa)
Sare_0137KEGG: stp:Strop_0132 ATPase involved in chromosome partitioning-like protein. (586 aa)
clpBATPase AAA-2 domain protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (863 aa)
Sare_0021TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein; KEGG: stp:Strop_0017 ATPase, P-type (transporting), HAD superfamily, subfamily IC. (1512 aa)
Sare_3304PFAM: protein of unknown function DUF59; KEGG: stp:Strop_3077 protein of unknown function DUF59. (140 aa)
Sare_3254PFAM: ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; KEGG: stp:Strop_3028 ATPase associated with various cellular activities, AAA_3. (371 aa)
Sare_3112PFAM: ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; KEGG: stp:Strop_2912 ATPase associated with various cellular activities, AAA_3. (331 aa)
Sare_3085KEGG: pac:PPA1616 UvrD/Rep helicase. (717 aa)
Sare_2927PFAM: ATPase associated with various cellular activities AAA_5; KEGG: stp:Strop_2019 ATPase associated with various cellular activities, AAA_5. (370 aa)
Sare_2847KEGG: stp:Strop_2578 hypothetical protein. (115 aa)
htpGHeat shock protein Hsp90; Molecular chaperone. Has ATPase activity. (636 aa)
Sare_2478PFAM: ABC transporter related; KEGG: stp:Strop_2335 ABC transporter related. (797 aa)
Sare_2464KEGG: stp:Strop_2578 hypothetical protein. (115 aa)
arcAAA ATPase central domain protein; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. (593 aa)
Sare_2308PFAM: UvrB/UvrC protein; AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: stp:Strop_2156 ATPase AAA-2 domain protein; Belongs to the ClpA/ClpB family. (848 aa)
lonATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (778 aa)
Sare_2192PFAM: UvrB/UvrC protein; AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: stp:Strop_4275 ATPase AAA-2 domain protein; Belongs to the ClpA/ClpB family. (836 aa)
Sare_1939PFAM: NERD domain protein; KEGG: fal:FRAAL5342 hypothetical protein; putative DNA helicase II homolog. (700 aa)
Sare_1924KEGG: pna:Pnap_0963 hypothetical protein. (616 aa)
Your Current Organism:
Salinispora arenicola
NCBI taxonomy Id: 391037
Other names: S. arenicola CNS-205, Salinispora arenicola CNS-205, Salinispora arenicola str. CNS-205, Salinispora arenicola strain CNS-205
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