STRINGSTRING
Sare_0892 Sare_0892 Sare_0879 Sare_0879 Sare_0864 Sare_0864 Sare_0784 Sare_0784 trpS trpS pth pth rplY rplY metG metG Sare_0719 Sare_0719 Sare_0573 Sare_0573 Sare_0570 Sare_0570 Sare_0485 Sare_0485 Sare_0352 Sare_0352 Sare_0177 Sare_0177 argS argS Sare_0109 Sare_0109 Sare_0037 Sare_0037 valS valS infA infA rplO rplO rpmD rpmD rpsE rpsE rplR rplR rplF rplF rpsH rpsH rpsZ rpsZ rplE rplE rplX rplX bioD bioD Sare_1582 Sare_1582 Sare_1741 Sare_1741 thrS thrS Sare_1809 Sare_1809 aspS aspS alaS alaS efp efp bioA bioA Sare_1853 Sare_1853 def def fmt fmt infC infC rpmI rpmI rplT rplT pheS pheS pheT pheT tyrS tyrS Sare_2100 Sare_2100 Sare_2144 Sare_2144 Sare_2148 Sare_2148 Sare_2149 Sare_2149 Sare_2238 Sare_2238 egtA egtA Sare_2464 Sare_2464 def-2 def-2 Sare_2594 Sare_2594 Sare_2611 Sare_2611 rpmF-2 rpmF-2 Sare_2670 Sare_2670 accD accD Sare_2694 Sare_2694 Sare_2737 Sare_2737 Sare_2738 Sare_2738 Sare_2746 Sare_2746 Sare_2847 Sare_2847 rpmE2 rpmE2 rpmG1 rpmG1 rpmB-2 rpmB-2 rpsN rpsN Sare_2920 Sare_2920 Sare_2923 Sare_2923 Sare_2987 Sare_2987 Sare_3064 Sare_3064 Sare_3169 Sare_3169 Sare_3184 Sare_3184 Sare_3301 Sare_3301 Sare_3313 Sare_3313 Sare_3330 Sare_3330 Sare_3360 Sare_3360 Sare_3369 Sare_3369 leuS leuS proS-2 proS-2 panB panB gltX gltX Sare_3640 Sare_3640 glyQS glyQS lepA lepA rpsT rpsT rpmA rpmA rplU rplU ileS ileS valS-2 valS-2 Sare_3895 Sare_3895 Sare_3917 Sare_3917 Sare_3982 Sare_3982 prfA prfA rpmE rpmE argS-2 argS-2 rplN rplN rpsQ rpsQ rpmC rpmC rplP rplP rpsC rpsC rplV rplV rpsD rpsD rplQ rplQ Sare_4282 Sare_4282 rplM rplM rpsI rpsI ackA ackA Sare_4072 Sare_4072 rpmH rpmH rpsF rpsF rpsR rpsR rplI rplI Sare_5051 Sare_5051 Sare_4997 Sare_4997 Sare_4945 Sare_4945 Sare_4941 Sare_4941 Sare_4933 Sare_4933 Sare_4917 Sare_4917 Sare_4896 Sare_4896 Sare_4866 Sare_4866 rpsD-2 rpsD-2 Sare_4740 Sare_4740 Sare_4732 Sare_4732 Sare_4731 Sare_4731 Sare_4730 Sare_4730 panC panC panD panD lysS lysS def-4 def-4 Sare_4687 Sare_4687 cysS cysS Sare_4563 Sare_4563 glyQ glyQ acsA acsA Sare_4342 Sare_4342 rpmG2 rpmG2 rplK rplK rplA rplA rplJ rplJ rplL rplL rpsL rpsL rpsG rpsG fusA fusA tuf tuf rpsJ rpsJ rplC rplC rplD rplD rplW rplW rplB rplB rpsS rpsS rpsK rpsK rpsM rpsM rpmJ rpmJ Sare_1519 Sare_1519 bioB bioB rpsO rpsO infB infB Sare_1265 Sare_1265 frr frr tsf tsf rpsB rpsB rplS rplS rpsP rpsP proS proS rpmF rpmF rpmB rpmB Sare_1145 Sare_1145 Sare_1139 Sare_1139 gatB gatB gatA gatA gatC gatC Sare_1044 Sare_1044 smpB smpB prfB prfB
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
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gene neighborhood
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Sare_0892PFAM: aminotransferase class-III; KEGG: stp:Strop_0950 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (448 aa)
Sare_0879TIGRFAM: acetoacetyl-CoA synthase; PFAM: AMP-dependent synthetase and ligase; KEGG: stp:Strop_0937 acetoacetyl-CoA synthase. (664 aa)
Sare_0864PFAM: Amidase; KEGG: stp:Strop_0921 amidase. (466 aa)
Sare_0784TIGRFAM: threonyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein; KEGG: stp:Strop_0841 tRNA synthetase, class II (G, H, P and S). (405 aa)
trpStryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (341 aa)
pthAminoacyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. (196 aa)
rplYRibosomal 5S rRNA E-loop binding protein Ctc/L25/TL5; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. (234 aa)
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (600 aa)
Sare_0719PFAM: 4'-phosphopantetheinyl transferase; KEGG: stp:Strop_0777 4'-phosphopantetheinyl transferase; Belongs to the P-Pant transferase superfamily. (347 aa)
Sare_0573PFAM: phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; KEGG: rha:RHA1_ro08658 possible dehydrogenase. (420 aa)
Sare_0570Methionine--tRNA ligase; PFAM: Cupin 2 conserved barrel domain protein; tRNA synthetase class I (M); KEGG: pen:PSEEN0982 methionine--tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. (659 aa)
Sare_0485PFAM: protein of unknown function DUF201; KEGG: cac:CA_P0138 hypothetical protein. (453 aa)
Sare_0352PFAM: MbtH domain protein; KEGG: sma:SAV3644 putative MbtH-like protein. (63 aa)
Sare_0177Sterol 3-beta-glucosyltransferase; PFAM: UDP-glucuronosyl/UDP-glucosyltransferase; glycosyl transferase family 28; KEGG: stp:Strop_0168 sterol 3-beta-glucosyltransferase. (427 aa)
argSKEGG: stp:Strop_0146 arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase. (572 aa)
Sare_0109PFAM: dehydrogenase E1 component; KEGG: stp:Strop_0109 pyruvate dehydrogenase (acetyl-transferring). (391 aa)
Sare_0037KEGG: stp:Strop_0031 hypothetical protein. (492 aa)
valStRNA synthetase valyl/leucyl anticodon-binding; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner. (862 aa)
infATranslation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (73 aa)
rplORibosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (147 aa)
rpmDPFAM: ribosomal protein L30; KEGG: stp:Strop_3905 ribosomal protein L30. (60 aa)
rpsERibosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family. (204 aa)
rplRRibosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (129 aa)
rplFRibosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (180 aa)
rpsHRibosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (135 aa)
rpsZRibosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site. (61 aa)
rplERibosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (189 aa)
rplXRibosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (106 aa)
bioDDethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (234 aa)
Sare_1582KEGG: stp:Strop_4126 hypothetical protein. (151 aa)
Sare_1741KEGG: stp:Strop_1755 hypothetical protein. (138 aa)
thrSTIGRFAM: threonyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein; Threonyl/alanyl tRNA synthetase SAD; KEGG: stp:Strop_1783 threonyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (671 aa)
Sare_1809Histidine--tRNA ligase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein; KEGG: stp:Strop_1819 histidine--tRNA ligase. (440 aa)
aspSaspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (604 aa)
alaSalanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (892 aa)
efpTranslation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. (185 aa)
bioAAdenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (425 aa)
Sare_1853KEGG: stp:Strop_1860 hypothetical protein. (105 aa)
defPeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (186 aa)
fmtmethionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (308 aa)
infCTranslation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. (239 aa)
rpmIPFAM: ribosomal protein L35; KEGG: stp:Strop_1883 ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family. (64 aa)
rplTRibosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (130 aa)
pheSTIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; PFAM: phenylalanyl-tRNA synthetase class IIc; aminoacyl tRNA synthetase class II domain protein; KEGG: stp:Strop_1886 phenylalanyl-tRNA synthetase, alpha subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (355 aa)
pheTKEGG: stp:Strop_1887 phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit. (861 aa)
tyrStyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (428 aa)
Sare_2100PFAM: aminotransferase class-III; KEGG: acr:Acry_0545 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (461 aa)
Sare_2144PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; KEGG: sco:SCO6898 carboxylase. (416 aa)
Sare_2148PFAM: protein of unknown function DUF201; KEGG: plu:plu0116 hypothetical protein. (414 aa)
Sare_2149Methionine--tRNA ligase; PFAM: tRNA synthetase class I (M); KEGG: sco:SCO6436 tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (536 aa)
Sare_2238PFAM: dehydrogenase E1 component; KEGG: stp:Strop_2097 pyruvate dehydrogenase (acetyl-transferring). (382 aa)
egtAGlutamate--cysteine ligase GCS2; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine. (411 aa)
Sare_2464KEGG: stp:Strop_2578 hypothetical protein. (115 aa)
def-2Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (168 aa)
Sare_2594KEGG: stp:Strop_2439 hypothetical protein. (187 aa)
Sare_2611KEGG: stp:Strop_2446 gamma-glutamyltransferase; TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase. (646 aa)
rpmF-2TIGRFAM: ribosomal protein L32; PFAM: ribosomal L32p protein; KEGG: nfa:nfa41850 putative ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. (59 aa)
Sare_2670PFAM: dehydrogenase E1 component; KEGG: stp:Strop_2487 dehydrogenase, E1 component. (323 aa)
accDacetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA (By similarity). In the N-terminal section; belongs to the AccD/PCCB family. (566 aa)
Sare_2694KEGG: stp:Strop_2510 hypothetical protein. (249 aa)
Sare_2737PFAM: IucA/IucC family protein; KEGG: stp:Strop_2548 IucA/IucC family protein. (596 aa)
Sare_2738KEGG: stp:Strop_2549 hypothetical protein. (188 aa)
Sare_2746KEGG: stp:Strop_2557 hypothetical protein. (191 aa)
Sare_2847KEGG: stp:Strop_2578 hypothetical protein. (115 aa)
rpmE2PFAM: ribosomal protein L31; KEGG: stp:Strop_2857 ribosomal protein L31. (87 aa)
rpmG1PFAM: ribosomal protein L33; KEGG: stp:Strop_2854 ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. (55 aa)
rpmB-2PFAM: ribosomal protein L28; KEGG: stp:Strop_2855 ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family. (78 aa)
rpsNRibosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (101 aa)
Sare_2920PFAM: aminotransferase class I and II; KEGG: stp:Strop_1720 aminotransferase, class I and II. (413 aa)
Sare_2923KEGG: stp:Strop_1717 hypothetical protein. (444 aa)
Sare_2987PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: stp:Strop_2015 ABC transporter related. (555 aa)
Sare_3064PFAM: protein of unknown function DUF201; KEGG: sco:SCO6437 hypothetical protein. (441 aa)
Sare_3169PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sco:SCO0636 ABC transporter ATP-binding protein. (541 aa)
Sare_31848-amino-7-oxononanoate synthase; PFAM: aminotransferase class I and II; aminotransferase class-III; KEGG: stp:Strop_1724 8-amino-7-oxononanoate synthase. (514 aa)
Sare_3301PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: stp:Strop_3074 ABC transporter related. (534 aa)
Sare_3313KEGG: stp:Strop_3086 hypothetical protein. (305 aa)
Sare_3330PFAM: RimK domain protein ATP-grasp; KEGG: stp:Strop_2425 hypothetical protein. (311 aa)
Sare_3360TIGRFAM: small GTP-binding protein; GTP-binding protein TypA; PFAM: elongation factor G domain protein; protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; KEGG: stp:Strop_3132 GTP-binding protein TypA. (622 aa)
Sare_3369PFAM: RNA binding S1 domain protein; KEGG: stp:Strop_3140 RNA binding S1 domain protein. (493 aa)
leuSTIGRFAM: leucyl-tRNA synthetase; KEGG: stp:Strop_3225 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (952 aa)
proS-2prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] (584 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (281 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (469 aa)
Sare_3640KEGG: stp:Strop_3397 seryl-tRNA synthetase; TIGRFAM: seryl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Seryl-tRNA synthetase, class IIa-like. (427 aa)
glyQSglycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family. (459 aa)
lepAGTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (640 aa)
rpsTRibosomal protein S20; Binds directly to 16S ribosomal RNA. (88 aa)
rpmAPFAM: ribosomal protein L27; KEGG: stp:Strop_3480 ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family. (84 aa)
rplURibosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (104 aa)
ileSisoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1059 aa)
valS-2valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (872 aa)
Sare_3895PFAM: Amidase; KEGG: stp:Strop_3520 amidase; Belongs to the amidase family. (488 aa)
Sare_3917PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: stp:Strop_3542 ABC transporter related. (558 aa)
Sare_3982KEGG: stp:Strop_3601 hypothetical protein. (127 aa)
prfAPeptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (362 aa)
rpmERibosomal protein L31; Binds the 23S rRNA. (74 aa)
argS-2KEGG: stp:Strop_3653 arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase. (554 aa)
rplNRibosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (122 aa)
rpsQRibosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (91 aa)
rpmCPFAM: ribosomal protein L29; KEGG: stp:Strop_3915 ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family. (78 aa)
rplPRibosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (141 aa)
rpsCRibosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (288 aa)
rplVRibosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). (152 aa)
rpsDRNA-binding S4 domain protein; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (208 aa)
rplQPFAM: ribosomal protein L17; KEGG: stp:Strop_3894 ribosomal protein L17. (190 aa)
Sare_4282PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: stp:Strop_3891 ABC transporter related. (559 aa)
rplMRibosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (147 aa)
rpsIPFAM: ribosomal protein S9; KEGG: stp:Strop_3863 ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. (154 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (375 aa)
Sare_4072Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (689 aa)
rpmHPFAM: ribosomal protein L34; KEGG: stp:Strop_4593 ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family. (45 aa)
rpsFRibosomal protein S6; Binds together with S18 to 16S ribosomal RNA. (96 aa)
rpsRRibosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (79 aa)
rplIRibosomal protein L9; Binds to the 23S rRNA. (148 aa)
Sare_5051KEGG: stp:Strop_4541 hypothetical protein. (301 aa)
Sare_4997KEGG: stp:Strop_4483 hypothetical protein. (289 aa)
Sare_4945PFAM: aminotransferase class-III; KEGG: bms:BRA1166 hypothetical protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (439 aa)
Sare_4941Adenosylmethionine--8-amino-7-oxononanoate transaminase; PFAM: aminotransferase class-III; KEGG: ace:Acel_1287 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (452 aa)
Sare_4933PFAM: AMP-dependent synthetase and ligase; KEGG: tfu:Tfu_1871 2,3-dihydroxybenzoate-AMP ligase. (555 aa)
Sare_4917PFAM: RimK domain protein ATP-grasp; KEGG: stp:Strop_2425 hypothetical protein. (318 aa)
Sare_4896PFAM: MbtH domain protein; KEGG: stp:Strop_4421 MbtH domain protein. (69 aa)
Sare_4866KEGG: stp:Strop_0101 hypothetical protein. (112 aa)
rpsD-2RNA-binding S4 domain protein; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (202 aa)
Sare_4740KEGG: stp:Strop_4304 hypothetical protein. (186 aa)
Sare_4732Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (291 aa)
Sare_4731Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (120 aa)
Sare_4730TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; KEGG: stp:Strop_4295 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase. (175 aa)
panCPantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (282 aa)
panDAspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (141 aa)
lysSKEGG: stp:Strop_4277 lysyl-tRNA synthetase; TIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; Belongs to the class-II aminoacyl-tRNA synthetase family. (502 aa)
def-4Formylmethionine deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (187 aa)
Sare_4687KEGG: stp:Strop_4257 hypothetical protein. (287 aa)
cysSKEGG: stp:Strop_4222 cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia DALR; Cysteinyl-tRNA synthetase class Ia; Belongs to the class-I aminoacyl-tRNA synthetase family. (471 aa)
Sare_4563PFAM: MbtH domain protein; KEGG: sco:SCO3218 putative small conserved hypothetical protein. (71 aa)
glyQglycyl-tRNA synthetase, beta subunit; KEGG: fra:Francci3_1275 glycine--tRNA ligase; TIGRFAM: glycyl-tRNA synthetase, alpha subunit; glycyl-tRNA synthetase, beta subunit; PFAM: glycyl-tRNA synthetase alpha subunit; glycyl-tRNA synthetase beta subunit. (993 aa)
acsAacetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (661 aa)
Sare_4342KEGG: stp:Strop_3957 hypothetical protein. (420 aa)
rpmG2PFAM: ribosomal protein L33; KEGG: stp:Strop_3942 ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family. (55 aa)
rplKRibosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (143 aa)
rplARibosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (238 aa)
rplJRibosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (181 aa)
rplLRibosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (129 aa)
rpsLRibosomal protein S12; With S4 and S5 plays an important role in translational accuracy. (124 aa)
rpsGRibosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa)
fusATranslation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] (698 aa)
tufTranslation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (397 aa)
rpsJRibosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa)
rplCRibosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (219 aa)
rplDRibosomal protein L4/L1e; Forms part of the polypeptide exit tunnel. (216 aa)
rplWRibosomal protein L25/L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (100 aa)
rplBRibosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (279 aa)
rpsSRibosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (93 aa)
rpsKRibosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (135 aa)
rpsMRibosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (126 aa)
rpmJPFAM: ribosomal protein L36; KEGG: stp:Strop_3899 ribosomal protein L36; Belongs to the bacterial ribosomal protein bL36 family. (37 aa)
Sare_15198-amino-7-oxononanoate synthase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; aminotransferase class-III; KEGG: stp:Strop_1570 8-amino-7-oxononanoate synthase. (378 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (331 aa)
rpsORibosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. (89 aa)
infBTranslation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (995 aa)
Sare_1265PFAM: aminotransferase class-III; KEGG: bcy:Bcer98_1682 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (449 aa)
frrRibosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. (185 aa)
tsfTranslation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. (275 aa)
rpsBPFAM: ribosomal protein S2; KEGG: stp:Strop_1322 ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. (279 aa)
rplSRibosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (118 aa)
rpsPPFAM: ribosomal protein S16; KEGG: stp:Strop_1305 ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. (158 aa)
proSprolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (468 aa)
rpmFTIGRFAM: ribosomal protein L32; PFAM: ribosomal L32p protein; KEGG: stp:Strop_1285 ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. (57 aa)
rpmBPFAM: ribosomal protein L28; KEGG: stp:Strop_1277 ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family. (63 aa)
Sare_1145TIGRFAM: tryptophanyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ib; KEGG: pcu:pc0170 putative tryptophanyl-tRNA synthetase (=tryptophan-tRNA ligase). (352 aa)
Sare_1139PFAM: Class I peptide chain release factor; KEGG: stp:Strop_1249 class I peptide chain release factor. (135 aa)
gatBglutamyl-tRNA(Gln) amidotransferase, B subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (499 aa)
gatAglutamyl-tRNA(Gln) amidotransferase, A subunit; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (491 aa)
gatCglutamyl-tRNA(Gln) amidotransferase, C subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (101 aa)
Sare_1044Methionine--tRNA ligase; PFAM: Cupin 2 conserved barrel domain protein; tRNA synthetase class I (M); KEGG: fra:Francci3_3273 cupin 2; Belongs to the class-I aminoacyl-tRNA synthetase family. (671 aa)
smpBSsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] (159 aa)
prfBPeptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. (373 aa)
Your Current Organism:
Salinispora arenicola
NCBI taxonomy Id: 391037
Other names: S. arenicola CNS-205, Salinispora arenicola CNS-205, Salinispora arenicola str. CNS-205, Salinispora arenicola strain CNS-205
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