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Sare_0107 Sare_0107 Sare_0108 Sare_0108 Sare_0109 Sare_0109 Sare_0511 Sare_0511 Sare_0645 Sare_0645 Sare_0646 Sare_0646 pckG pckG Sare_1114 Sare_1114 Sare_1705 Sare_1705 Sare_1706 Sare_1706 Sare_1707 Sare_1707 Sare_2238 Sare_2238 Sare_2239 Sare_2239 Sare_2240 Sare_2240 Sare_2284 Sare_2284 Sare_3289 Sare_3289 Sare_3551 Sare_3551 Sare_3552 Sare_3552 Sare_3613 Sare_3613 Sare_4070 Sare_4070 Sare_4150 Sare_4150 Sare_4151 Sare_4151 Sare_4173 Sare_4173 Sare_4174 Sare_4174 sucD sucD sucC sucC fumC fumC Sare_4675 Sare_4675
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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Your Input:
Sare_0107PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: stp:Strop_0107 catalytic domain of components of various dehydrogenase complexes. (490 aa)
Sare_0108PFAM: Transketolase central region; Transketolase domain protein; KEGG: stp:Strop_0108 transketolase, central region. (329 aa)
Sare_0109PFAM: dehydrogenase E1 component; KEGG: stp:Strop_0109 pyruvate dehydrogenase (acetyl-transferring). (391 aa)
Sare_0511PFAM: Citrate synthase; KEGG: stp:Strop_0423 citrate (Si)-synthase; Belongs to the citrate synthase family. (368 aa)
Sare_0645PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: stp:Strop_0698 thiamine pyrophosphate enzyme domain protein TPP-binding. (344 aa)
Sare_0646PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: stp:Strop_0699 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. (615 aa)
pckGPhosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (612 aa)
Sare_1114Transketolase domain protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (785 aa)
Sare_1705TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: stp:Strop_1708 succinate dehydrogenase and fumarate reductase iron-sulfur protein. (251 aa)
Sare_1706KEGG: stp:Strop_1709 succinate dehydrogenase or fumarate reductase, flavoprotein subunit; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein. (643 aa)
Sare_1707TIGRFAM: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family; KEGG: stp:Strop_1710 succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family. (230 aa)
Sare_2238PFAM: dehydrogenase E1 component; KEGG: stp:Strop_2097 pyruvate dehydrogenase (acetyl-transferring). (382 aa)
Sare_2239PFAM: Transketolase central region; Transketolase domain protein; KEGG: stp:Strop_2098 transketolase, central region. (334 aa)
Sare_2240PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: stp:Strop_2099 catalytic domain of components of various dehydrogenase complexes. (430 aa)
Sare_2284KEGG: stp:Strop_2136 citrate synthase I; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family. (427 aa)
Sare_3289TIGRFAM: aconitate hydratase 1; PFAM: aconitate hydratase domain protein; KEGG: stp:Strop_3062 aconitate hydratase 1. (948 aa)
Sare_3551TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD dependent oxidoreductase; KEGG: stp:Strop_3319 dihydrolipoamide dehydrogenase. (462 aa)
Sare_35522-oxoglutarate dehydrogenase E2 component; KEGG: stp:Strop_3320 dihydrolipoyllysine-residue succinyltransferase; TIGRFAM: 2-oxoglutarate dehydrogenase E2 component; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein. (590 aa)
Sare_36132-oxo-acid dehydrogenase E1 subunit, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (912 aa)
Sare_4070TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: dehydrogenase E1 component; catalytic domain of components of various dehydrogenase complexes; Transketolase central region; KEGG: stp:Strop_3690 2-oxoglutarate dehydrogenase, E1 subunit. (1237 aa)
Sare_4150PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; KEGG: stp:Strop_3768 succinate dehydrogenase. (637 aa)
Sare_4151TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: ferredoxin; KEGG: stp:Strop_3769 succinate dehydrogenase and fumarate reductase iron-sulfur protein. (366 aa)
Sare_4173KEGG: stp:Strop_3793 isocitrate dehydrogenase, NADP-dependent; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (404 aa)
Sare_4174Lactate/malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. (316 aa)
sucDsuccinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (295 aa)
sucCsuccinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (392 aa)
fumCFumarate lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (466 aa)
Sare_4675Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (555 aa)
Your Current Organism:
Salinispora arenicola
NCBI taxonomy Id: 391037
Other names: S. arenicola CNS-205, Salinispora arenicola CNS-205, Salinispora arenicola str. CNS-205, Salinispora arenicola strain CNS-205
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