STRINGSTRING
Sare_0028 Sare_0028 speE speE Sare_0265 Sare_0265 Sare_0266 Sare_0266 Sare_0340 Sare_0340 Sare_0510 Sare_0510 Sare_0518 Sare_0518 Sare_0567 Sare_0567 Sare_0630 Sare_0630 Sare_0855 Sare_0855 Sare_0863 Sare_0863 ahcY ahcY Sare_0922 Sare_0922 Sare_1126 Sare_1126 Sare_1130 Sare_1130 Sare_1158 Sare_1158 Sare_1421 Sare_1421 Sare_1736 Sare_1736 metK metK Sare_1925 Sare_1925 Sare_2059 Sare_2059 egtA egtA Sare_2325 Sare_2325 Sare_2784 Sare_2784 Sare_2956 Sare_2956 asd asd Sare_4033 Sare_4033 Sare_4174 Sare_4174 Sare_4509 Sare_4509 Sare_4585 Sare_4585
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
Sare_0028PFAM: Rhodanese domain protein; KEGG: kra:Krad_3079 rhodanese domain protein. (297 aa)
speESpermine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. (519 aa)
Sare_0265KEGG: stp:Strop_0226 aspartate kinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; Belongs to the aspartokinase family. (421 aa)
Sare_0266KEGG: stp:Strop_0227 aspartate-semialdehyde dehydrogenase; TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase NAD - binding; Semialdehyde dehydrogenase dimerisation region; Belongs to the aspartate-semialdehyde dehydrogenase family. (353 aa)
Sare_0340PFAM: Rhodanese domain protein; KEGG: stp:Strop_0296 rhodanese domain protein. (282 aa)
Sare_0510Putative phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (375 aa)
Sare_0518KEGG: stp:Strop_0430 L-serine dehydratase 1; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. (465 aa)
Sare_0567PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: mka:MK0297 predicted dehydrogenase related to phosphoglycerate dehydrogenase. (345 aa)
Sare_0630Quorum-sensing autoinducer 2 (AI-2), LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (165 aa)
Sare_0855TIGRFAM: cystathionine beta-synthase; PFAM: CBS domain containing protein; Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: stp:Strop_0912 cystathionine beta-synthase. (456 aa)
Sare_0863Cystathionine gamma-synthase; PFAM: aminotransferase class V; Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: stp:Strop_0920 cystathionine gamma-synthase. (380 aa)
ahcYAdenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (496 aa)
Sare_0922Methylthioadenosine phosphorylase; Purine nucleoside phosphorylase involved in purine salvage. (267 aa)
Sare_1126TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: amino acid-binding ACT domain protein; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: stp:Strop_1236 D-3-phosphoglycerate dehydrogenase. (531 aa)
Sare_1130TIGRFAM: branched-chain amino acid aminotransferase; PFAM: aminotransferase class IV; KEGG: stp:Strop_1240 branched-chain amino acid aminotransferase. (365 aa)
Sare_1158PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: stp:Strop_1267 Cys/Met metabolism pyridoxal-phosphate-dependent enzyme. (373 aa)
Sare_1421PFAM: Rhodanese domain protein; KEGG: stp:Strop_1460 rhodanese domain protein. (288 aa)
Sare_1736KEGG: stp:Strop_0966 adenosylhomocysteinase; TIGRFAM: adenosylhomocysteinase; PFAM: S-adenosyl-L-homocysteine hydrolase; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; S-adenosyl-L-homocysteine hydrolase, NAD binding. (496 aa)
metKMethionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (399 aa)
Sare_1925KEGG: stp:Strop_0061 C-5 cytosine-specific DNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (98 aa)
Sare_2059PFAM: purine or other phosphorylase family 1; KEGG: stp:Strop_4371 purine or other phosphorylase, family 1. (384 aa)
egtAGlutamate--cysteine ligase GCS2; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine. (411 aa)
Sare_2325Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1171 aa)
Sare_2784PFAM: aminotransferase class I and II; KEGG: stp:Strop_2586 aminotransferase, class I and II. (421 aa)
Sare_2956TIGRFAM: cystathionine beta-synthase; PFAM: CBS domain containing protein; Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: tfu:Tfu_0438 cystathionine beta-synthase. (465 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (341 aa)
Sare_4033PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; KEGG: stp:Strop_3651 homoserine dehydrogenase. (437 aa)
Sare_4174Lactate/malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. (316 aa)
Sare_4509PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: stp:Strop_4089 pyridoxal-5'-phosphate-dependent enzyme, beta subunit. (363 aa)
Sare_4585PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: stp:Strop_2310 pyridoxal-5'-phosphate-dependent enzyme, beta subunit. (335 aa)
Your Current Organism:
Salinispora arenicola
NCBI taxonomy Id: 391037
Other names: S. arenicola CNS-205, Salinispora arenicola CNS-205, Salinispora arenicola str. CNS-205, Salinispora arenicola strain CNS-205
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