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Sare_0238 Sare_0238 Sare_0588 Sare_0588 Sare_0771 Sare_0771 Sare_0996 Sare_0996 hutI hutI hutU hutU Sare_1872 Sare_1872 hisG hisG egtB egtB egtC egtC egtD egtD Sare_2802 Sare_2802 hisI hisI hisF hisF hisA hisA hisH hisH hisB hisB hisC hisC hisD hisD Sare_3922 Sare_3922 Sare_4101 Sare_4101 pat pat
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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gene co-occurrence
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textmining
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Sare_0238PFAM: aldehyde dehydrogenase; KEGG: stp:Strop_0078 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (474 aa)
Sare_0588ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. (217 aa)
Sare_0771PFAM: aldehyde dehydrogenase; KEGG: stp:Strop_0827 aldehyde dehydrogenase (NAD(+)); Belongs to the aldehyde dehydrogenase family. (476 aa)
Sare_0996KEGG: stp:Strop_1106 histidine ammonia-lyase; TIGRFAM: histidine ammonia-lyase; PFAM: phenylalanine/histidine ammonia-lyase. (512 aa)
hutIKEGG: stp:Strop_1107 imidazolonepropionase; TIGRFAM: imidazolonepropionase; PFAM: amidohydrolase; Amidohydrolase 3; Belongs to the metallo-dependent hydrolases superfamily. HutI family. (392 aa)
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (549 aa)
Sare_1872PFAM: phosphoribosyl-ATP pyrophosphohydrolase; KEGG: stp:Strop_1879 phosphoribosyl-ATP pyrophosphohydrolase; Belongs to the PRA-PH family. (100 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (294 aa)
egtBProtein of unknown function DUF323; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family. (444 aa)
egtCConserved hypothetical protein; Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. (248 aa)
egtDConserved hypothetical protein; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family. (321 aa)
Sare_2802PFAM: aldehyde dehydrogenase; KEGG: stp:Strop_2603 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (502 aa)
hisIPhosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (147 aa)
hisFImidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (255 aa)
hisAKEGG: stp:Strop_3190 bifunctional HisA/TrpF protein; TIGRFAM: bifunctional HisA/TrpF protein; PFAM: histidine biosynthesis protein. (241 aa)
hisHImidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (210 aa)
hisBPFAM: imidazoleglycerol-phosphate dehydratase; KEGG: stp:Strop_3194 imidazoleglycerol-phosphate dehydratase. (203 aa)
hisCTIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; KEGG: stp:Strop_3195 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (358 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (440 aa)
Sare_3922PFAM: aminotransferase class I and II; KEGG: stp:Strop_3547 aminotransferase, class I and II. (366 aa)
Sare_4101TIGRFAM: histidinol-phosphate phosphatase, putative; PFAM: inositol monophosphatase; KEGG: stp:Strop_3720 histidinol-phosphate phosphatase, putative. (272 aa)
patHistidinol-phosphate aminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (367 aa)
Your Current Organism:
Salinispora arenicola
NCBI taxonomy Id: 391037
Other names: S. arenicola CNS-205, Salinispora arenicola CNS-205, Salinispora arenicola str. CNS-205, Salinispora arenicola strain CNS-205
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