STRINGSTRING
Sare_0031 Sare_0031 Sare_0107 Sare_0107 Sare_0108 Sare_0108 Sare_0109 Sare_0109 Sare_0148 Sare_0148 Sare_0238 Sare_0238 leuA leuA Sare_0645 Sare_0645 Sare_0646 Sare_0646 Sare_0771 Sare_0771 Sare_0792 Sare_0792 pckG pckG ppc ppc Sare_0851 Sare_0851 Sare_0895 Sare_0895 Sare_1114 Sare_1114 Sare_1133 Sare_1133 Sare_1316 Sare_1316 Sare_1406 Sare_1406 Sare_1808 Sare_1808 Sare_1999 Sare_1999 Sare_2225 Sare_2225 Sare_2238 Sare_2238 Sare_2239 Sare_2239 Sare_2240 Sare_2240 Sare_2687 Sare_2687 Sare_2688 Sare_2688 Sare_2802 Sare_2802 Sare_2807 Sare_2807 Sare_2812 Sare_2812 Sare_2841 Sare_2841 Sare_2892 Sare_2892 Sare_3196 Sare_3196 Sare_3238 Sare_3238 Sare_3385 Sare_3385 Sare_3551 Sare_3551 Sare_3613 Sare_3613 Sare_3624 Sare_3624 Sare_3806 Sare_3806 Sare_3901 Sare_3901 Sare_3991 Sare_3991 Sare_4072 Sare_4072 ackA ackA Sare_4075 Sare_4075 Sare_4093 Sare_4093 Sare_4174 Sare_4174 acsA acsA Sare_4547 Sare_4547 Sare_4566 Sare_4566 fumC fumC Sare_4675 Sare_4675
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
Sare_0031PFAM: phosphoribosylglycinamide synthetase; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: stp:Strop_0025 carbamoyl-phosphate synthase L chain, ATP-binding. (445 aa)
Sare_0107PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: stp:Strop_0107 catalytic domain of components of various dehydrogenase complexes. (490 aa)
Sare_0108PFAM: Transketolase central region; Transketolase domain protein; KEGG: stp:Strop_0108 transketolase, central region. (329 aa)
Sare_0109PFAM: dehydrogenase E1 component; KEGG: stp:Strop_0109 pyruvate dehydrogenase (acetyl-transferring). (391 aa)
Sare_0148TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; KEGG: stp:Strop_0142 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (430 aa)
Sare_0238PFAM: aldehyde dehydrogenase; KEGG: stp:Strop_0078 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (474 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (584 aa)
Sare_0645PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: stp:Strop_0698 thiamine pyrophosphate enzyme domain protein TPP-binding. (344 aa)
Sare_0646PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: stp:Strop_0699 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. (615 aa)
Sare_0771PFAM: aldehyde dehydrogenase; KEGG: stp:Strop_0827 aldehyde dehydrogenase (NAD(+)); Belongs to the aldehyde dehydrogenase family. (476 aa)
Sare_0792Carbamoyl-phosphate synthase L chain ATP-binding; PFAM: biotin/lipoyl attachment domain-containing protein; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: stp:Strop_0849 carbamoyl-phosphate synthase L chain, ATP-binding. (583 aa)
pckGPhosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (612 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (928 aa)
Sare_0851KEGG: stp:Strop_0908 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (420 aa)
Sare_0895PFAM: aldehyde dehydrogenase; KEGG: stp:Strop_0957 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (501 aa)
Sare_1114Transketolase domain protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (785 aa)
Sare_1133TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain; KEGG: stp:Strop_1243 2-isopropylmalate synthase/homocitrate synthase family protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. (527 aa)
Sare_1316KEGG: stp:Strop_1359 beta-ketoadipyl CoA thiolase; TIGRFAM: acetyl-CoA acetyltransferase; beta-ketoadipyl CoA thiolase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa)
Sare_1406Malate dehydrogenase (oxaloacetate-decarboxylating); PFAM: malic protein domain protein; malic protein NAD-binding; KEGG: stp:Strop_1448 malate dehydrogenase (oxaloacetate-decarboxylating). (490 aa)
Sare_1808PFAM: beta-lactamase domain protein; KEGG: stp:Strop_1818 beta-lactamase domain protein. (238 aa)
Sare_1999PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase. (133 aa)
Sare_2225PFAM: beta-lactamase domain protein; SMART: Rhodanese domain protein; KEGG: stp:Strop_2086 beta-lactamase domain protein. (470 aa)
Sare_2238PFAM: dehydrogenase E1 component; KEGG: stp:Strop_2097 pyruvate dehydrogenase (acetyl-transferring). (382 aa)
Sare_2239PFAM: Transketolase central region; Transketolase domain protein; KEGG: stp:Strop_2098 transketolase, central region. (334 aa)
Sare_2240PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: stp:Strop_2099 catalytic domain of components of various dehydrogenase complexes. (430 aa)
Sare_2687PFAM: phosphoribosylglycinamide synthetase; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: stp:Strop_2503 carbamoyl-phosphate synthase L chain, ATP-binding. (458 aa)
Sare_2688acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (205 aa)
Sare_2802PFAM: aldehyde dehydrogenase; KEGG: stp:Strop_2603 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (502 aa)
Sare_2807KEGG: stp:Strop_2608 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (377 aa)
Sare_2812KEGG: stp:Strop_2613 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (387 aa)
Sare_2841KEGG: stp:Strop_2644 propanoyl-CoA C-acyltransferase. (392 aa)
Sare_2892PFAM: beta-lactamase domain protein; SMART: Rhodanese domain protein; KEGG: stp:Strop_1960 beta-lactamase domain protein. (452 aa)
Sare_3196PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: stp:Strop_2972 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. (333 aa)
Sare_3238PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: mxa:MXAN_3857 pyruvate dehydrogenase; Belongs to the TPP enzyme family. (614 aa)
Sare_3385KEGG: stp:Strop_3160 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family. (482 aa)
Sare_3551TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD dependent oxidoreductase; KEGG: stp:Strop_3319 dihydrolipoamide dehydrogenase. (462 aa)
Sare_36132-oxo-acid dehydrogenase E1 subunit, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (912 aa)
Sare_3624Propionyl-CoA carboxylase; PFAM: carboxyl transferase; KEGG: stp:Strop_3382 propionyl-CoA carboxylase. (474 aa)
Sare_3806KEGG: stp:Strop_3429 pyruvate, phosphate dikinase; TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilizing protein; pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; Belongs to the PEP-utilizing enzyme family. (911 aa)
Sare_3901Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (308 aa)
Sare_3991KEGG: stp:Strop_3610 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (399 aa)
Sare_4072Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (689 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (375 aa)
Sare_4075Malate dehydrogenase (oxaloacetate-decarboxylating); PFAM: malic protein domain protein; malic protein NAD-binding; KEGG: stp:Strop_3695 malate dehydrogenase (oxaloacetate-decarboxylating). (391 aa)
Sare_4093PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: stp:Strop_3712 biotin/lipoyl attachment domain-containing protein. (73 aa)
Sare_4174Lactate/malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. (316 aa)
acsAacetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (661 aa)
Sare_4547PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; KEGG: mxa:MXAN_6800 phosphoenolpyruvate synthase. (386 aa)
Sare_4566Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (295 aa)
fumCFumarate lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (466 aa)
Sare_4675Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (555 aa)
Your Current Organism:
Salinispora arenicola
NCBI taxonomy Id: 391037
Other names: S. arenicola CNS-205, Salinispora arenicola CNS-205, Salinispora arenicola str. CNS-205, Salinispora arenicola strain CNS-205
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