STRINGSTRING
Bphy_0186 Bphy_0186 Bphy_0228 Bphy_0228 Bphy_0287 Bphy_0287 msrA msrA Bphy_0540 Bphy_0540 Bphy_0634 Bphy_0634 dsbB dsbB Bphy_0921 Bphy_0921 Bphy_0950 Bphy_0950 ahpD ahpD Bphy_1001 Bphy_1001 Bphy_1774 Bphy_1774 Bphy_1775 Bphy_1775 Bphy_1968 Bphy_1968 Bphy_2188 Bphy_2188 Bphy_2439 Bphy_2439 tpx tpx Bphy_2706 Bphy_2706 Bphy_2805 Bphy_2805 Bphy_2806 Bphy_2806 dsbD dsbD Bphy_3656 Bphy_3656 Bphy_3657 Bphy_3657 Bphy_3740 Bphy_3740 Bphy_4109 Bphy_4109 Bphy_4263 Bphy_4263 Bphy_4264 Bphy_4264 Bphy_4265 Bphy_4265 Bphy_4266 Bphy_4266 Bphy_4267 Bphy_4267 Bphy_4316 Bphy_4316 selA selA selD selD Bphy_5001 Bphy_5001 Bphy_5033 Bphy_5033 msrA-2 msrA-2 Bphy_5424 Bphy_5424 Bphy_5425 Bphy_5425
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Bphy_0186PFAM: DSBA oxidoreductase; KEGG: bxe:Bxe_A4247 putative thiol-disulfide interchange protein. (212 aa)
Bphy_0228Redoxin domain protein; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: bxe:Bxe_A4194 putative thiol-disulfide isomerase and thioredoxins. (174 aa)
Bphy_0287Electron transport protein SCO1/SenC; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; electron transport protein SCO1/SenC; KEGG: bxe:Bxe_A4161 electron transport protein SCO1/SenC. (205 aa)
msrAPeptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (183 aa)
Bphy_0540Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (192 aa)
Bphy_0634TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: bxe:Bxe_A3442 thioredoxin reductase. (333 aa)
dsbBDisulphide bond formation protein DsbB; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family. (168 aa)
Bphy_0921PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: bxe:Bxe_A2391 putative bacterioferritin comigratory oxidoreductase. (153 aa)
Bphy_0950TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: bxe:Bxe_A2362 thioredoxin; Belongs to the thioredoxin family. (108 aa)
ahpDAlkylhydroperoxidase like protein, AhpD family; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. (174 aa)
Bphy_1001PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: bxe:Bxe_A2309 putative alkyl hydroperoxide reductase subunit C. (182 aa)
Bphy_1774KEGG: bxe:Bxe_A2910 putative signal peptide transmembrane protein. (154 aa)
Bphy_1775PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: bxe:Bxe_A2911 putative peroxiredoxin, bacterioferritin comigratory protein. (187 aa)
Bphy_1968PFAM: Heavy metal transport/detoxification protein; KEGG: bxe:Bxe_A3162 heavy metal binding protein. (69 aa)
Bphy_2188PFAM: superoxide dismutase copper/zinc binding; KEGG: bxe:Bxe_A3479 putative copper/zinc superoxide dismutase. (206 aa)
Bphy_2439Peroxidase; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: bxe:Bxe_A3905 peroxidase. (212 aa)
tpxRedoxin domain protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily. (166 aa)
Bphy_2706Putative thiol-disulfide interchange protein, DsbC; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily. (241 aa)
Bphy_2805TIGRFAM: cytochrome c-type biogenesis protein CcsB; PFAM: cytochrome c assembly protein; KEGG: bxe:Bxe_A0348 cytochrome c assembly protein. (405 aa)
Bphy_2806PFAM: ResB family protein; KEGG: bxe:Bxe_A0347 cytochrome c biogenesis protein. (741 aa)
dsbDProtein-disulfide reductase; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. (618 aa)
Bphy_3656TIGRFAM: alkyl hydroperoxide reductase, F subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: bxe:Bxe_B1206 AhpF. (530 aa)
Bphy_3657Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. (187 aa)
Bphy_3740PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: bvi:Bcep1808_6193 FAD-dependent pyridine nucleotide-disulphide oxidoreductase. (351 aa)
Bphy_4109PFAM: Thioredoxin domain; KEGG: bxe:Bxe_B1336 putative thioredoxin. (107 aa)
Bphy_4263PFAM: protein of unknown function DUF1006; KEGG: bxe:Bxe_B2989 hypothetical protein. (404 aa)
Bphy_4264KEGG: bxe:Bxe_B2988 hypothetical protein. (97 aa)
Bphy_4265PFAM: cyclic nucleotide-binding; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; HI0933 family protein; KEGG: bxe:Bxe_B2987 cyclic nucleotide-regulated FAD-dependent pyridine nucleotide-disulphide oxidoreductase. (567 aa)
Bphy_4266SMART: Rhodanese domain protein; KEGG: bxe:Bxe_B2986 putative DedA protein. (329 aa)
Bphy_4267KEGG: bxe:Bxe_B2985 hypothetical protein. (83 aa)
Bphy_4316Heavy metal translocating P-type ATPase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper ion binding protein; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: bvi:Bcep1808_3665 heavy metal translocating P-type ATPase. (835 aa)
selAL-seryl-tRNA(Sec) selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. (478 aa)
selDSelenide, water dikinase; Synthesizes selenophosphate from selenide and ATP. (353 aa)
Bphy_5001KEGG: bte:BTH_II0363 hypothetical protein. (90 aa)
Bphy_5033Redoxin domain protein; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; cytochrome c biogenesis protein transmembrane region; Redoxin domain protein; KEGG: bch:Bcen2424_6244 cytochrome c biogenesis protein, transmembrane region. (581 aa)
msrA-2Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (245 aa)
Bphy_5424Redoxin domain protein; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; cytochrome c biogenesis protein transmembrane region; Redoxin domain protein; KEGG: bxe:Bxe_B0816 putative transmembrane protein. (604 aa)
Bphy_5425TIGRFAM: methionine-R-sulfoxide reductase; PFAM: Methionine sulfoxide reductase B; KEGG: bur:Bcep18194_C6665 methionine sulfoxide reductase B. (174 aa)
Your Current Organism:
Paraburkholderia phymatum
NCBI taxonomy Id: 391038
Other names: Burkholderia phymatum STM815, Burkholderia sp. STM815, P. phymatum STM815, Paraburkholderia phymatum STM815
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