STRINGSTRING
queF queF Bphy_0510 Bphy_0510 Bphy_0782 Bphy_0782 folD folD Bphy_1515 Bphy_1515 Bphy_1567 Bphy_1567 Bphy_1755 Bphy_1755 proC proC Bphy_2916 Bphy_2916 Bphy_3018 Bphy_3018 mnmC mnmC Bphy_3161 Bphy_3161 Bphy_3189 Bphy_3189 Bphy_3300 Bphy_3300 Bphy_3330 Bphy_3330 Bphy_3331 Bphy_3331 Bphy_3332 Bphy_3332 Bphy_4078 Bphy_4078 Bphy_4312 Bphy_4312 Bphy_4827 Bphy_4827
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
queF7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). (274 aa)
Bphy_0510PFAM: flavin reductase domain protein FMN-binding; KEGG: bxe:Bxe_A0737 putative flavin reductase-like protein. (174 aa)
Bphy_0782Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (166 aa)
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (285 aa)
Bphy_1515PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; HI0933 family protein; KEGG: bxe:Bxe_A1452 2,4-dienoyl-CoA reductase FadH2. (686 aa)
Bphy_1567Electron-transferring-flavoprotein dehydrogenase; Accepts electrons from ETF and reduces ubiquinone. (557 aa)
Bphy_1755PFAM: NAD-dependent epimerase/dehydratase; KEGG: bxe:Bxe_A2862 putative NADH-flavin reductase protein. (215 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (271 aa)
Bphy_2916KEGG: bxe:Bxe_A0180 5,10-methylenetetrahydrofolate reductase; TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (276 aa)
Bphy_3018Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1320 aa)
mnmCtRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family. (655 aa)
Bphy_3161PFAM: FAD dependent oxidoreductase; glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: bxe:Bxe_B1666 dehydrogenase; Belongs to the GcvT family. (827 aa)
Bphy_3189PFAM: flavin reductase domain protein FMN-binding; KEGG: psp:PSPPH_2161 flavin reductase domain protein. (172 aa)
Bphy_3300PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: bxe:Bxe_B1582 NADH-flavin oxidoreductase / NADH oxidase family protein. (687 aa)
Bphy_3330PFAM: Sarcosine oxidase gamma subunit; KEGG: bam:Bamb_4543 sarcosine oxidase, gamma subunit. (216 aa)
Bphy_3331TIGRFAM: sarcosine oxidase, alpha subunit family; PFAM: FAD dependent oxidoreductase; glycine cleavage T protein (aminomethyl transferase); FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Glycine cleavage T-protein barrel; KEGG: bch:Bcen2424_5149 sarcosine oxidase, alpha subunit family; Belongs to the GcvT family. (999 aa)
Bphy_3332PFAM: Sarcosine oxidase delta subunit heterotetrameric; KEGG: bxe:Bxe_B1599 SoxD. (99 aa)
Bphy_4078PFAM: flavin reductase domain protein FMN-binding; KEGG: bxe:Bxe_B0249 putative flavin reductase. (204 aa)
Bphy_4312KEGG: bxe:Bxe_B2943 hypothetical protein. (205 aa)
Bphy_4827Electron-transferring-flavoprotein dehydrogenase; Accepts electrons from ETF and reduces ubiquinone. (555 aa)
Your Current Organism:
Paraburkholderia phymatum
NCBI taxonomy Id: 391038
Other names: Burkholderia phymatum STM815, Burkholderia sp. STM815, P. phymatum STM815, Paraburkholderia phymatum STM815
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