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folE folE ABI61037.1 ABI61037.1 hisC hisC aroC aroC dadA dadA aroK aroK ABI61613.1 ABI61613.1 ABI61614.1 ABI61614.1 ABI61616.1 ABI61616.1 ABI61658.1 ABI61658.1 trpC trpC trpD trpD ABI61719.1 ABI61719.1 trpE trpE ABI61885.1 ABI61885.1 ABI62009.1 ABI62009.1 ABI62019.1 ABI62019.1 aroQ aroQ ABI62892.1 ABI62892.1 ABI62910.1 ABI62910.1 trpA trpA trpB trpB trpF trpF aroA aroA aroE aroE ABI63116.1 ABI63116.1
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
folEGTP cyclohydrolase I. (217 aa)
ABI61037.1Prephenate dehydrogenase. (295 aa)
hisCHistidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (370 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (375 aa)
dadAD-amino acid dehydrogenase small subunit; Oxidative deamination of D-amino acids; Belongs to the DadA oxidoreductase family. (418 aa)
aroKShikimate kinase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (590 aa)
ABI61613.1Aspartate aminotransferase. (400 aa)
ABI61614.1Aspartate aminotransferase. (400 aa)
ABI61616.1Tyrosine decarboxylase. (491 aa)
ABI61658.1Para-aminobenzoate synthase glutamine amidotransferase component II. (725 aa)
trpCIndole-3-glycerol phosphate synthase; Belongs to the TrpC family. (305 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (346 aa)
ABI61719.1Para-aminobenzoate synthase glutamine amidotransferase component II. (206 aa)
trpEAnthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (512 aa)
ABI61885.12-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. (185 aa)
ABI62009.1Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (348 aa)
ABI62019.1D-alanine aminotransferase. (288 aa)
aroQ3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (267 aa)
ABI62892.1Prephenate dehydratase. (295 aa)
ABI62910.1Dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family. (430 aa)
trpATryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (278 aa)
trpBTryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (407 aa)
trpFN-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. (209 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (454 aa)
aroEShikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (289 aa)
ABI63116.1Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (360 aa)
Your Current Organism:
Granulibacter bethesdensis
NCBI taxonomy Id: 391165
Other names: G. bethesdensis CGDNIH1, Granulibacter bethesdensis CGDNIH1, Granulibacter bethesdensis str. CGDNIH1, Granulibacter bethesdensis strain CGDNIH1
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