(37 nodes) Mixed, incl. UBX domain, and Endoplasmic reticulum to cytosol transport network (Enhydra lutris)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC111141539	NSFL1 cofactor p47 isoform X1. (372 aa)
	LOC111141898	Protein sel-1 homolog 2. (776 aa)
	LOC111141166	FAS-associated factor 2. (445 aa)
	LOC111143022	UBX domain-containing protein 4. (507 aa)
	LOC111142640	Ubiquitin recognition factor in ER-associated degradation protein 1 isoform X1. (307 aa)
	LOC111142757	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (241 aa)
	LOC111144587	LRP2-binding protein. (360 aa)
	LOC111142863	FAS-associated factor 1 isoform X1. (658 aa)
	LOC111144539	UBX domain-containing protein 8 isoform X1. (282 aa)
	LOC111146592	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (252 aa)
	LOC111145449	Transitional endoplasmic reticulum ATPase isoform X1; Belongs to the AAA ATPase family. (806 aa)
	LOC111146713	E3 ubiquitin-protein ligase RNF139. (664 aa)
	LOC111147109	Ubiquitin-associated domain-containing protein 2. (344 aa)
	LOC111148525	Protein sel-1 homolog 1. (794 aa)
	LOC111149500	UBX domain-containing protein 1 isoform X1. (296 aa)
	LOC111147966	Endoplasmic reticulum lectin 1 isoform X1. (499 aa)
	LOC111148023	Ancient ubiquitous protein 1 isoform X1. (466 aa)
	LOC111151065	Ubiquitin thioesterase OTU1. (348 aa)
	LOC111149412	E3 ubiquitin-protein ligase synoviolin isoform X1. (611 aa)
	LOC111152181	E3 ubiquitin-protein ligase RNF5. (180 aa)
	LOC111150037	Small VCP/p97-interacting protein. (77 aa)
	LOC111152796	Dentin sialophosphoprotein-like. (637 aa)
	LOC111154619	Ubiquitin conjugation factor E4 B isoform X1. (1311 aa)
	LOC111154827	UBX domain-containing protein 10. (271 aa)
	LOC111154172	UBX domain-containing protein 2A isoform X1. (257 aa)
	LOC111154288	Spermatogenesis-associated protein 5. (893 aa)
	LOC111155024	UBX domain-containing protein 7. (489 aa)
	LOC111155459	UBX domain-containing protein 2B. (330 aa)
	LOC111160064	E3 ubiquitin-protein ligase RNF185. (192 aa)
	LOC111160175	Protein OS-9 isoform X1. (670 aa)
	LOC111157345	E3 ubiquitin-protein ligase AMFR. (643 aa)
	LOC111161113	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (239 aa)
	LOC111159866	Phospholipase A-2-activating protein isoform X1. (796 aa)
	LOC111161207	Spermatogenesis-associated protein 5-like protein 1 isoform X1. (767 aa)
	LOC111160312	Nuclear protein localization protein 4 homolog. (608 aa)
	LOC111160425	Tether containing UBX domain for GLUT4 isoform X1. (619 aa)
	LOC111161886	UBX domain-containing protein 6. (442 aa)

Your Current Organism:

Enhydra lutris

NCBI taxonomy Id: 391180
Other names: E. lutris kenyoni, Enhydra lutris kenyoni

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC111141166	LOC111141539	A0A2Y9IPH1	A0A2Y9IMT9	FAS-associated factor 2.	NSFL1 cofactor p47 isoform X1.	0.466
LOC111141166	LOC111141898	A0A2Y9IPH1	A0A2Y9INY6	FAS-associated factor 2.	Protein sel-1 homolog 2.	0.495
LOC111141166	LOC111142640	A0A2Y9IPH1	A0A2Y9J0P1	FAS-associated factor 2.	Ubiquitin recognition factor in ER-associated degradation protein 1 isoform X1.	0.954
LOC111141166	LOC111142757	A0A2Y9IPH1	A0A2Y9J0Z5	FAS-associated factor 2.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.617
LOC111141166	LOC111143022	A0A2Y9IPH1	A0A2Y9IUW4	FAS-associated factor 2.	UBX domain-containing protein 4.	0.630
LOC111141166	LOC111144539	A0A2Y9IPH1	A0A2Y9J4B8	FAS-associated factor 2.	UBX domain-containing protein 8 isoform X1.	0.514
LOC111141166	LOC111144587	A0A2Y9IPH1	A0A2Y9J1C3	FAS-associated factor 2.	LRP2-binding protein.	0.408
LOC111141166	LOC111145449	A0A2Y9IPH1	A0A2Y9JE35	FAS-associated factor 2.	Transitional endoplasmic reticulum ATPase isoform X1; Belongs to the AAA ATPase family.	0.965
LOC111141166	LOC111146592	A0A2Y9IPH1	A0A2Y9JE17	FAS-associated factor 2.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.615
LOC111141166	LOC111146713	A0A2Y9IPH1	A0A2Y9JEI8	FAS-associated factor 2.	E3 ubiquitin-protein ligase RNF139.	0.493
LOC111141166	LOC111147109	A0A2Y9IPH1	A0A2Y9JLH8	FAS-associated factor 2.	Ubiquitin-associated domain-containing protein 2.	0.968
LOC111141166	LOC111147966	A0A2Y9IPH1	A0A2Y9JQA6	FAS-associated factor 2.	Endoplasmic reticulum lectin 1 isoform X1.	0.619
LOC111141166	LOC111148023	A0A2Y9IPH1	A0A2Y9JQJ3	FAS-associated factor 2.	Ancient ubiquitous protein 1 isoform X1.	0.757
LOC111141166	LOC111148525	A0A2Y9IPH1	A0A2Y9JMR5	FAS-associated factor 2.	Protein sel-1 homolog 1.	0.768
LOC111141166	LOC111149412	A0A2Y9IPH1	A0A2Y9JX24	FAS-associated factor 2.	E3 ubiquitin-protein ligase synoviolin isoform X1.	0.630
LOC111141166	LOC111149500	A0A2Y9IPH1	A0A2Y9JMX4	FAS-associated factor 2.	UBX domain-containing protein 1 isoform X1.	0.956
LOC111141166	LOC111152796	A0A2Y9IPH1	A0A2Y9K651	FAS-associated factor 2.	Dentin sialophosphoprotein-like.	0.456
LOC111141166	LOC111154172	A0A2Y9IPH1	A0A2Y9KCM8	FAS-associated factor 2.	UBX domain-containing protein 2A isoform X1.	0.474
LOC111141166	LOC111154288	A0A2Y9IPH1	A0A2Y9KJM1	FAS-associated factor 2.	Spermatogenesis-associated protein 5.	0.697
LOC111141166	LOC111154619	A0A2Y9IPH1	A0A2Y9K9C5	FAS-associated factor 2.	Ubiquitin conjugation factor E4 B isoform X1.	0.499