(15 nodes) Mixed, incl. Oligodendrocyte cell fate commitment, and Astrocyte end-foot network (Enhydra lutris)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC111138945	LOW QUALITY PROTEIN: nestin; Belongs to the intermediate filament family. (1629 aa)
	LOC111140686	Forkhead box protein G1. (491 aa)
	LOC111142638	Aquaporin-4 isoform X1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (323 aa)
	LOC111142856	Microtubule-associated protein. (1919 aa)
	LOC111144119	Synapsin-2. (579 aa)
	LOC111144313	DNA-binding protein SATB. (733 aa)
	LOC111145325	T-box brain protein 1. (682 aa)
	LOC111146355	Homeobox protein cut-like. (1552 aa)
	LOC111148191	Homeobox protein EMX1 isoform X1. (295 aa)
	LOC111149573	Paired box protein Pax-6 isoform X1. (436 aa)
	LOC111150487	Synaptophysin. (313 aa)
	LOC111155822	Oligodendrocyte transcription factor 2. (378 aa)
	LOC111155452	Peroxidasin-like protein. (1466 aa)
	LOC111158105	Glial fibrillary acidic protein isoform X1; Belongs to the intermediate filament family. (432 aa)
	LOC111160967	Neuronal migration protein doublecortin. (365 aa)

Your Current Organism:

Enhydra lutris

NCBI taxonomy Id: 391180
Other names: E. lutris kenyoni, Enhydra lutris kenyoni

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC111138945	LOC111140686	A0A2Y9IDI0	A0A2Y9IK43	LOW QUALITY PROTEIN: nestin; Belongs to the intermediate filament family.	Forkhead box protein G1.	0.757
LOC111138945	LOC111142856	A0A2Y9IDI0	A0A2Y9IX45	LOW QUALITY PROTEIN: nestin; Belongs to the intermediate filament family.	Microtubule-associated protein.	0.714
LOC111138945	LOC111144119	A0A2Y9IDI0	A0A2Y9IZC0	LOW QUALITY PROTEIN: nestin; Belongs to the intermediate filament family.	Synapsin-2.	0.441
LOC111138945	LOC111144313	A0A2Y9IDI0	A0A2Y9J046	LOW QUALITY PROTEIN: nestin; Belongs to the intermediate filament family.	DNA-binding protein SATB.	0.707
LOC111138945	LOC111145325	A0A2Y9IDI0	A0A2Y9J853	LOW QUALITY PROTEIN: nestin; Belongs to the intermediate filament family.	T-box brain protein 1.	0.762
LOC111138945	LOC111146355	A0A2Y9IDI0	A0A2Y9JD36	LOW QUALITY PROTEIN: nestin; Belongs to the intermediate filament family.	Homeobox protein cut-like.	0.699
LOC111138945	LOC111148191	A0A2Y9IDI0	A0A2Y9JH74	LOW QUALITY PROTEIN: nestin; Belongs to the intermediate filament family.	Homeobox protein EMX1 isoform X1.	0.441
LOC111138945	LOC111149573	A0A2Y9IDI0	A0A2Y9JMR1	LOW QUALITY PROTEIN: nestin; Belongs to the intermediate filament family.	Paired box protein Pax-6 isoform X1.	0.737
LOC111138945	LOC111150487	A0A2Y9IDI0	A0A2Y9JSJ7	LOW QUALITY PROTEIN: nestin; Belongs to the intermediate filament family.	Synaptophysin.	0.576
LOC111138945	LOC111155452	A0A2Y9IDI0	A0A2Y9KIP7	LOW QUALITY PROTEIN: nestin; Belongs to the intermediate filament family.	Peroxidasin-like protein.	0.491
LOC111138945	LOC111155822	A0A2Y9IDI0	A0A2Y9KDS4	LOW QUALITY PROTEIN: nestin; Belongs to the intermediate filament family.	Oligodendrocyte transcription factor 2.	0.846
LOC111138945	LOC111158105	A0A2Y9IDI0	A0A2Y9KWH6	LOW QUALITY PROTEIN: nestin; Belongs to the intermediate filament family.	Glial fibrillary acidic protein isoform X1; Belongs to the intermediate filament family.	0.606
LOC111138945	LOC111160967	A0A2Y9IDI0	A0A2Y9L2F4	LOW QUALITY PROTEIN: nestin; Belongs to the intermediate filament family.	Neuronal migration protein doublecortin.	0.750
LOC111140686	LOC111138945	A0A2Y9IK43	A0A2Y9IDI0	Forkhead box protein G1.	LOW QUALITY PROTEIN: nestin; Belongs to the intermediate filament family.	0.757
LOC111140686	LOC111144313	A0A2Y9IK43	A0A2Y9J046	Forkhead box protein G1.	DNA-binding protein SATB.	0.754
LOC111140686	LOC111145325	A0A2Y9IK43	A0A2Y9J853	Forkhead box protein G1.	T-box brain protein 1.	0.826
LOC111140686	LOC111146355	A0A2Y9IK43	A0A2Y9JD36	Forkhead box protein G1.	Homeobox protein cut-like.	0.488
LOC111140686	LOC111148191	A0A2Y9IK43	A0A2Y9JH74	Forkhead box protein G1.	Homeobox protein EMX1 isoform X1.	0.654
LOC111140686	LOC111149573	A0A2Y9IK43	A0A2Y9JMR1	Forkhead box protein G1.	Paired box protein Pax-6 isoform X1.	0.851
LOC111140686	LOC111155822	A0A2Y9IK43	A0A2Y9KDS4	Forkhead box protein G1.	Oligodendrocyte transcription factor 2.	0.441