(16 nodes) Outflow tract septum morphogenesis network (Enhydra lutris)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC111142438	Mothers against decapentaplegic homolog. (552 aa)
	LOC111141224	Homeobox protein Nkx-2.5. (323 aa)
	LOC111141287	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1045 aa)
	LOC111144836	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (533 aa)
	LOC111141989	Low-density lipoprotein receptor-related protein 2. (4705 aa)
	LOC111145249	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (247 aa)
	LOC111146591	Zinc finger protein ZFPM2. (1148 aa)
	LOC111147438	T-box transcription factor TBX20. (447 aa)
	LOC111145664	Endoglin isoform X1. (660 aa)
	LOC111151576	T-box transcription factor TBX2. (713 aa)
	LOC111153274	Mothers against decapentaplegic homolog. (497 aa)
	LOC111155291	semaphorin-3C; Belongs to the semaphorin family. (750 aa)
	LOC111158395	Neuropilin; Belongs to the neuropilin family. (931 aa)
	LOC111159418	Alpha-parvin. (372 aa)
	LOC111162047	Bone morphogenetic protein 4 isoform X1. (456 aa)
	LOC111142563	Transcription factor GATA-6. (592 aa)

Your Current Organism:

Enhydra lutris

NCBI taxonomy Id: 391180
Other names: E. lutris kenyoni, Enhydra lutris kenyoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC111141224	LOC111142563	A0A2Y9ITU2	A0A2Y9IS32	Homeobox protein Nkx-2.5.	Transcription factor GATA-6.	0.772
LOC111141224	LOC111146591	A0A2Y9ITU2	A0A2Y9JA88	Homeobox protein Nkx-2.5.	Zinc finger protein ZFPM2.	0.517
LOC111141224	LOC111147438	A0A2Y9ITU2	A0A2Y9JDR6	Homeobox protein Nkx-2.5.	T-box transcription factor TBX20.	0.674
LOC111141224	LOC111151576	A0A2Y9ITU2	A0A2Y9JWF8	Homeobox protein Nkx-2.5.	T-box transcription factor TBX2.	0.639
LOC111141224	LOC111162047	A0A2Y9ITU2	A0A2Y9LJR5	Homeobox protein Nkx-2.5.	Bone morphogenetic protein 4 isoform X1.	0.438
LOC111141287	LOC111142438	A0A2Y9IQ32	A0A2Y9ISJ5	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.800
LOC111141287	LOC111144836	A0A2Y9IQ32	A0A2Y9J3I8	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.977
LOC111141287	LOC111145664	A0A2Y9IQ32	A0A2Y9JFA2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Endoglin isoform X1.	0.502
LOC111141287	LOC111153274	A0A2Y9IQ32	A0A2Y9K338	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.729
LOC111141287	LOC111162047	A0A2Y9IQ32	A0A2Y9LJR5	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Bone morphogenetic protein 4 isoform X1.	0.990
LOC111142438	LOC111141287	A0A2Y9ISJ5	A0A2Y9IQ32	Mothers against decapentaplegic homolog.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.800
LOC111142438	LOC111142563	A0A2Y9ISJ5	A0A2Y9IS32	Mothers against decapentaplegic homolog.	Transcription factor GATA-6.	0.621
LOC111142438	LOC111144836	A0A2Y9ISJ5	A0A2Y9J3I8	Mothers against decapentaplegic homolog.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.812
LOC111142438	LOC111153274	A0A2Y9ISJ5	A0A2Y9K338	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.656
LOC111142438	LOC111162047	A0A2Y9ISJ5	A0A2Y9LJR5	Mothers against decapentaplegic homolog.	Bone morphogenetic protein 4 isoform X1.	0.849
LOC111142563	LOC111141224	A0A2Y9IS32	A0A2Y9ITU2	Transcription factor GATA-6.	Homeobox protein Nkx-2.5.	0.772
LOC111142563	LOC111142438	A0A2Y9IS32	A0A2Y9ISJ5	Transcription factor GATA-6.	Mothers against decapentaplegic homolog.	0.621
LOC111142563	LOC111146591	A0A2Y9IS32	A0A2Y9JA88	Transcription factor GATA-6.	Zinc finger protein ZFPM2.	0.756
LOC111142563	LOC111147438	A0A2Y9IS32	A0A2Y9JDR6	Transcription factor GATA-6.	T-box transcription factor TBX20.	0.415
LOC111142563	LOC111162047	A0A2Y9IS32	A0A2Y9LJR5	Transcription factor GATA-6.	Bone morphogenetic protein 4 isoform X1.	0.595