(27 nodes) ER to Golgi transport vesicle membrane network (Enhydra lutris)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC111143086	Peflin. (289 aa)
	LOC111143848	Protein SEC13 homolog; Belongs to the WD repeat SEC13 family. (322 aa)
	LOC111161007	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (765 aa)
	LOC111150817	Protein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. (1045 aa)
	LOC111148904	Protein transport protein Sec31A isoform X1. (1218 aa)
	LOC111148535	Vesicle transport through interaction with t-SNAREs homolog 1B. (232 aa)
	LOC111144868	Vacuolar ATPase assembly integral membrane protein vma21-like. (113 aa)
	LOC111145547	Protein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. (2335 aa)
	LOC111145345	GTP-binding protein SAR1a; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
	LOC111145830	Syntaxin-17; Belongs to the syntaxin family. (302 aa)
	LOC111144937	Vesicle transport through interaction with t-SNAREs homolog 1A isoform X1. (224 aa)
	LOC111144815	Protein transport protein Sec24C isoform X1. (1153 aa)
	LOC111143543	Vesicle-trafficking protein SEC22b; Belongs to the synaptobrevin family. (215 aa)
	LOC111143824	Sterol regulatory element-binding protein cleavage-activating protein isoform X1. (1279 aa)
	LOC111145238	Protein transport protein Sec31B isoform X1. (1243 aa)
	LOC111158179	Golgi SNAP receptor complex member 2 isoform X1; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. (212 aa)
	LOC111156051	Protein transport protein Sec24D-like. (510 aa)
	LOC111140979	Protein transport protein Sec24A isoform X1. (1100 aa)
	LOC111139145	Vacuolar ATPase assembly integral membrane protein VMA21; Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum. (101 aa)
	LOC111139729	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (145 aa)
	LOC111141093	GTP-binding protein SAR1b; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
	LOC111141534	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (767 aa)
	LOC111154050	Protein transport protein Sec24D isoform X1. (1032 aa)
	LOC111153827	Protein transport protein Sec24B isoform X1. (1261 aa)
	LOC111153395	Programmed cell death protein 6 isoform X1. (189 aa)
	LOC111149223	General vesicular transport factor p115 isoform X2. (974 aa)
	LOC111151124	Kelch-like protein 12 isoform X1. (604 aa)

Your Current Organism:

Enhydra lutris

NCBI taxonomy Id: 391180
Other names: E. lutris kenyoni, Enhydra lutris kenyoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC111139729	LOC111140979	A0A2Y9IKI3	A0A2Y9IK30	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Protein transport protein Sec24A isoform X1.	0.872
LOC111139729	LOC111141093	A0A2Y9IKI3	A0A2Y9IKJ2	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	GTP-binding protein SAR1b; Belongs to the small GTPase superfamily. SAR1 family.	0.758
LOC111139729	LOC111143543	A0A2Y9IKI3	A0A2Y9IWT2	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Vesicle-trafficking protein SEC22b; Belongs to the synaptobrevin family.	0.910
LOC111139729	LOC111143848	A0A2Y9IKI3	A0A2Y9J1F1	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Protein SEC13 homolog; Belongs to the WD repeat SEC13 family.	0.933
LOC111139729	LOC111144815	A0A2Y9IKI3	A0A2Y9J5N1	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Protein transport protein Sec24C isoform X1.	0.943
LOC111139729	LOC111145238	A0A2Y9IKI3	A0A2Y9J442	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Protein transport protein Sec31B isoform X1.	0.800
LOC111139729	LOC111145345	A0A2Y9IKI3	A0A2Y9J881	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	GTP-binding protein SAR1a; Belongs to the small GTPase superfamily. SAR1 family.	0.802
LOC111139729	LOC111145547	A0A2Y9IKI3	A0A2Y9J904	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Protein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus.	0.777
LOC111139729	LOC111145830	A0A2Y9IKI3	A0A2Y9J745	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Syntaxin-17; Belongs to the syntaxin family.	0.494
LOC111139729	LOC111148904	A0A2Y9IKI3	A0A2Y9JPB2	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Protein transport protein Sec31A isoform X1.	0.852
LOC111139729	LOC111149223	A0A2Y9IKI3	A0A2Y9JW25	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	General vesicular transport factor p115 isoform X2.	0.606
LOC111139729	LOC111150817	A0A2Y9IKI3	A0A2Y9JT21	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Protein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus.	0.777
LOC111139729	LOC111153827	A0A2Y9IKI3	A0A2Y9K6Q8	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Protein transport protein Sec24B isoform X1.	0.868
LOC111139729	LOC111154050	A0A2Y9IKI3	A0A2Y9K6T6	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Protein transport protein Sec24D isoform X1.	0.857
LOC111139729	LOC111156051	A0A2Y9IKI3	A0A2Y9KGU8	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Protein transport protein Sec24D-like.	0.857
LOC111139729	LOC111158179	A0A2Y9IKI3	A0A2Y9KWV4	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	Golgi SNAP receptor complex member 2 isoform X1; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.	0.780
LOC111140979	LOC111139729	A0A2Y9IK30	A0A2Y9IKI3	Protein transport protein Sec24A isoform X1.	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	0.872
LOC111140979	LOC111141093	A0A2Y9IK30	A0A2Y9IKJ2	Protein transport protein Sec24A isoform X1.	GTP-binding protein SAR1b; Belongs to the small GTPase superfamily. SAR1 family.	0.894
LOC111140979	LOC111141534	A0A2Y9IK30	A0A2Y9INT0	Protein transport protein Sec24A isoform X1.	Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.	0.932
LOC111140979	LOC111143543	A0A2Y9IK30	A0A2Y9IWT2	Protein transport protein Sec24A isoform X1.	Vesicle-trafficking protein SEC22b; Belongs to the synaptobrevin family.	0.958