(78 nodes) Synaptic vesicle membrane network (Enhydra lutris)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC111149113	Gamma-aminobutyric acid receptor subunit alpha-2; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (511 aa)
	LOC111150251	LOW QUALITY PROTEIN: synaptotagmin-8. (420 aa)
	LOC111150577	Synapsin-1 isoform X1. (704 aa)
	LOC111148384	Synaptic vesicle glycoprotein 2C. (724 aa)
	LOC111150487	Synaptophysin. (313 aa)
	LOC111149966	Vesicular glutamate transporter 2. (582 aa)
	LOC111151060	Synaptotagmin-2 isoform X2. (422 aa)
	LOC111151299	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (870 aa)
	LOC111152351	Tumor protein p63-regulated gene 1 protein. (279 aa)
	LOC111152600	Multiple C2 and transmembrane domain-containing protein 2 isoform X1. (878 aa)
	LOC111157506	Synaptogyrin. (234 aa)
	LOC111157509	Synapsin-3 isoform X2. (580 aa)
	LOC111161349	Dynamin-1-like protein isoform X4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (749 aa)
	LOC111162053	Synaptic vesicle glycoprotein 2A. (742 aa)
	LOC111160629	Vesicular glutamate transporter 1 isoform X1. (561 aa)
	LOC111161127	Vesicle-associated membrane protein 2. (116 aa)
	LOC111160828	Synaptogyrin. (234 aa)
	LOC111162213	Double C2-like domain-containing protein alpha isoform X1. (416 aa)
	LOC111160418	Synaptogyrin. (224 aa)
	LOC111159822	V-type proton ATPase subunit E 1 isoform X1. (226 aa)
	LOC111158470	Zinc transporter 3. (388 aa)
	LOC111159673	Vesicle-associated membrane protein 1. (138 aa)
	LOC111157071	Chromaffin granule amine transporter. (525 aa)
	LOC111159617	Synaptotagmin-9 isoform X1. (495 aa)
	LOC111156284	Synaptogyrin-3. (316 aa)
	LOC111156019	Ras-related protein Rab-26. (255 aa)
	LOC111156039	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa)
	LOC111156520	Synaptic vesicle 2-related protein. (548 aa)
	LOC111155865	semaphorin-4C; Belongs to the semaphorin family. (832 aa)
	LOC111158993	Ras-related protein Rab-7a isoform X1. (207 aa)
	LOC111152576	Synaptic vesicle glycoprotein 2B. (713 aa)
	LOC111152394	Proline-rich transmembrane protein 1. (306 aa)
	LOC111152825	UPF0183 protein C16orf70 homolog isoform X1. (422 aa)
	LOC111150515	Renin receptor isoform X1. (351 aa)
	LOC111153001	E3 ubiquitin-protein ligase ZNRF1. (227 aa)
	LOC111150879	Syntaxin-6; Belongs to the syntaxin family. (255 aa)
	LOC111153228	Complexin-3. (158 aa)
	LOC111153260	Protein unc-13 homolog C isoform X2. (2215 aa)
	LOC111154097	Otoferlin isoform X1. (1998 aa)
	LOC111138931	SNARE-associated protein Snapin. (139 aa)
	LOC111155258	Synaptophysin-like protein 1. (258 aa)
	LOC111153222	Secretory carrier-associated membrane protein. (235 aa)
	LOC111155079	Ras-related protein Rab-5A. (215 aa)
	LOC111156654	Dysbindin. (342 aa)
	LOC111156279	Sodium/hydrogen exchanger 9B2. (489 aa)
	LOC111156435	rabphilin-3A isoform X2. (702 aa)
	LOC111154585	Tumor protein p63-regulated gene 1-like protein isoform X1. (273 aa)
	LOC111162497	Syntaxin-10 isoform X1. (249 aa)
	LOC111139189	V-type proton ATPase subunit S1. (464 aa)
	LOC111140062	Synaptotagmin-5. (409 aa)
	LOC111140858	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (229 aa)
	LOC111140968	Glutamate receptor 1 isoform X1. (906 aa)
	LOC111155049	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (511 aa)
	LOC111141416	Transmembrane protein 163. (289 aa)
	LOC111139407	Synaptosomal-associated protein 47. (415 aa)
	LOC111141655	Lysosome-associated membrane glycoprotein 5 isoform X1. (280 aa)
	LOC111140964	Septin-8 isoform X1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (482 aa)
	LOC111141928	Vesicular inhibitory amino acid transporter. (526 aa)
	LOC111142135	Synaptotagmin-1. (422 aa)
	LOC111142172	BLOC-1-related complex subunit 5 isoform X1. (196 aa)
	LOC111142249	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1249 aa)
	LOC111143450	Ras-related protein Rab-3B. (219 aa)
	LOC111143510	Syntaxin-12; Belongs to the syntaxin family. (274 aa)
	LOC111141918	Synapse differentiation-inducing gene protein 1. (258 aa)
	LOC111143801	Ras-related protein Rab-3A. (220 aa)
	LOC111142222	Vesicular glutamate transporter 3 isoform X1. (588 aa)
	LOC111143320	Synaptophysin-like protein 2. (268 aa)
	LOC111144119	Synapsin-2. (579 aa)
	LOC111144141	Protein unc-13 homolog A. (1711 aa)
	LOC111144220	Synaptoporin isoform X1. (285 aa)
	LOC111143397	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (727 aa)
	LOC111145222	Synaptic vesicular amine transporter. (517 aa)
	LOC111145614	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (248 aa)
	LOC111145919	Protein unc-13 homolog B. (1610 aa)
	LOC111146645	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (384 aa)
	LOC111147277	Islet cell autoantigen 1 isoform X1. (510 aa)
	LOC111148337	Multiple C2 and transmembrane domain-containing protein 1. (998 aa)
	LOC111148292	Secretory carrier-associated membrane protein. (338 aa)

Your Current Organism:

Enhydra lutris

NCBI taxonomy Id: 391180
Other names: E. lutris kenyoni, Enhydra lutris kenyoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC111138931	LOC111142172	A0A2Y9IKU5	A0A2Y9IQU2	SNARE-associated protein Snapin.	BLOC-1-related complex subunit 5 isoform X1.	0.792
LOC111138931	LOC111156654	A0A2Y9IKU5	A0A2Y9KHS4	SNARE-associated protein Snapin.	Dysbindin.	0.908
LOC111138931	LOC111159673	A0A2Y9IKU5	A0A2Y9KXV9	SNARE-associated protein Snapin.	Vesicle-associated membrane protein 1.	0.580
LOC111138931	LOC111161127	A0A2Y9IKU5	A0A2Y9L9S0	SNARE-associated protein Snapin.	Vesicle-associated membrane protein 2.	0.670
LOC111138931	LOC111161349	A0A2Y9IKU5	A0A2Y9LGA7	SNARE-associated protein Snapin.	Dynamin-1-like protein isoform X4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.413
LOC111139189	LOC111146645	A0A2Y9IEM5	A0A2Y9JAF2	V-type proton ATPase subunit S1.	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.997
LOC111139189	LOC111150515	A0A2Y9IEM5	A0A2Y9K1X6	V-type proton ATPase subunit S1.	Renin receptor isoform X1.	0.998
LOC111139189	LOC111151299	A0A2Y9IEM5	A0A2Y9JZI0	V-type proton ATPase subunit S1.	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.	0.999
LOC111139189	LOC111155049	A0A2Y9IEM5	A0A2Y9KAN7	V-type proton ATPase subunit S1.	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family.	0.975
LOC111139189	LOC111156039	A0A2Y9IEM5	A0A2Y9KLR1	V-type proton ATPase subunit S1.	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.998
LOC111139189	LOC111159822	A0A2Y9IEM5	A0A2Y9KYI8	V-type proton ATPase subunit S1.	V-type proton ATPase subunit E 1 isoform X1.	0.997
LOC111139407	LOC111141928	A0A2Y9IMT2	A0A2Y9IP49	Synaptosomal-associated protein 47.	Vesicular inhibitory amino acid transporter.	0.468
LOC111139407	LOC111143510	A0A2Y9IMT2	A0A2Y9IWM4	Synaptosomal-associated protein 47.	Syntaxin-12; Belongs to the syntaxin family.	0.635
LOC111139407	LOC111150879	A0A2Y9IMT2	A0A2Y9K3K2	Synaptosomal-associated protein 47.	Syntaxin-6; Belongs to the syntaxin family.	0.443
LOC111139407	LOC111159673	A0A2Y9IMT2	A0A2Y9KXV9	Synaptosomal-associated protein 47.	Vesicle-associated membrane protein 1.	0.676
LOC111139407	LOC111161127	A0A2Y9IMT2	A0A2Y9L9S0	Synaptosomal-associated protein 47.	Vesicle-associated membrane protein 2.	0.749
LOC111139407	LOC111162497	A0A2Y9IMT2	A0A2Y9LGE5	Synaptosomal-associated protein 47.	Syntaxin-10 isoform X1.	0.443
LOC111140062	LOC111159673	A0A2Y9IHN5	A0A2Y9KXV9	Synaptotagmin-5.	Vesicle-associated membrane protein 1.	0.465
LOC111140062	LOC111161127	A0A2Y9IHN5	A0A2Y9L9S0	Synaptotagmin-5.	Vesicle-associated membrane protein 2.	0.504
LOC111140858	LOC111142135	A0A2Y9IJI5	A0A2Y9IQN1	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	Synaptotagmin-1.	0.509