(23 nodes) Regulation of osteoblast proliferation network (Enhydra lutris)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

co-expression

protein homology

Your Input:
	LOC111141184	Atrial natriuretic peptide receptor 3 isoform X1. (539 aa)
	LOC111140644	Gremlin-1 isoform X1. (240 aa)
	LOC111141639	LOW QUALITY PROTEIN: bone morphogenetic protein 2. (395 aa)
	LOC111143137	Protein CYR61. (382 aa)
	LOC111144126	Lactotransferrin isoform X1; Belongs to the transferrin family. (708 aa)
	LOC111144443	Secreted frizzled-related protein 1. (314 aa)
	LOC111144482	Secreted frizzled-related protein 1-like. (250 aa)
	LOC111146116	Tyrosine-protein kinase. (1149 aa)
	LOC111146720	Collagen triple helix repeat-containing protein 1 isoform X1. (244 aa)
	LOC111149020	Heparanase isoform X1. (544 aa)
	LOC111150553	Erythroid transcription factor. (414 aa)
	LOC111149489	Low-density lipoprotein receptor-related protein 5. (2138 aa)
	LOC111150918	tenascin-N. (1472 aa)
	LOC111153179	Mothers against decapentaplegic homolog. (425 aa)
	LOC111155043	Integrin alpha-V isoform X1; Belongs to the integrin alpha chain family. (1045 aa)
	LOC111156418	Transmembrane protein 119. (287 aa)
	LOC111156095	Transcription factor SOX-8. (462 aa)
	LOC111158107	Integrin beta; Belongs to the integrin beta chain family. (784 aa)
	LOC111158358	All-trans retinoic acid-induced differentiation factor isoform X1. (229 aa)
	LOC111158088	Axin-2 isoform X1. (843 aa)
	LOC111160001	Merlin isoform X1. (596 aa)
	LOC111158436	Interferon-induced, double-stranded RNA-activated protein kinase. (541 aa)
	LOC111160057	LOW QUALITY PROTEIN: transcriptional activator MN1. (1329 aa)

Your Current Organism:

Enhydra lutris

NCBI taxonomy Id: 391180
Other names: E. lutris kenyoni, Enhydra lutris kenyoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC111140644	LOC111141639	A0A2Y9IMH2	A0A2Y9IRW7	Gremlin-1 isoform X1.	LOW QUALITY PROTEIN: bone morphogenetic protein 2.	0.700
LOC111141639	LOC111140644	A0A2Y9IRW7	A0A2Y9IMH2	LOW QUALITY PROTEIN: bone morphogenetic protein 2.	Gremlin-1 isoform X1.	0.700
LOC111141639	LOC111153179	A0A2Y9IRW7	A0A2Y9K3C9	LOW QUALITY PROTEIN: bone morphogenetic protein 2.	Mothers against decapentaplegic homolog.	0.581
LOC111143137	LOC111160001	A0A2Y9IYC1	A0A2Y9KXR7	Protein CYR61.	Merlin isoform X1.	0.433
LOC111144126	LOC111149489	A0A2Y9IZC9	A0A2Y9JXI4	Lactotransferrin isoform X1; Belongs to the transferrin family.	Low-density lipoprotein receptor-related protein 5.	0.522
LOC111144443	LOC111149489	A0A2Y9J0L6	A0A2Y9JXI4	Secreted frizzled-related protein 1.	Low-density lipoprotein receptor-related protein 5.	0.561
LOC111144443	LOC111158088	A0A2Y9J0L6	A0A2Y9KR71	Secreted frizzled-related protein 1.	Axin-2 isoform X1.	0.559
LOC111144482	LOC111149489	A0A2Y9J1S2	A0A2Y9JXI4	Secreted frizzled-related protein 1-like.	Low-density lipoprotein receptor-related protein 5.	0.561
LOC111144482	LOC111158088	A0A2Y9J1S2	A0A2Y9KR71	Secreted frizzled-related protein 1-like.	Axin-2 isoform X1.	0.559
LOC111149489	LOC111144126	A0A2Y9JXI4	A0A2Y9IZC9	Low-density lipoprotein receptor-related protein 5.	Lactotransferrin isoform X1; Belongs to the transferrin family.	0.522
LOC111149489	LOC111144443	A0A2Y9JXI4	A0A2Y9J0L6	Low-density lipoprotein receptor-related protein 5.	Secreted frizzled-related protein 1.	0.561
LOC111149489	LOC111144482	A0A2Y9JXI4	A0A2Y9J1S2	Low-density lipoprotein receptor-related protein 5.	Secreted frizzled-related protein 1-like.	0.561
LOC111149489	LOC111158088	A0A2Y9JXI4	A0A2Y9KR71	Low-density lipoprotein receptor-related protein 5.	Axin-2 isoform X1.	0.859
LOC111150918	LOC111155043	A0A2Y9JXQ7	A0A2Y9KCF4	tenascin-N.	Integrin alpha-V isoform X1; Belongs to the integrin alpha chain family.	0.935
LOC111150918	LOC111158107	A0A2Y9JXQ7	A0A2Y9KPK4	tenascin-N.	Integrin beta; Belongs to the integrin beta chain family.	0.943
LOC111153179	LOC111141639	A0A2Y9K3C9	A0A2Y9IRW7	Mothers against decapentaplegic homolog.	LOW QUALITY PROTEIN: bone morphogenetic protein 2.	0.581
LOC111155043	LOC111150918	A0A2Y9KCF4	A0A2Y9JXQ7	Integrin alpha-V isoform X1; Belongs to the integrin alpha chain family.	tenascin-N.	0.935
LOC111155043	LOC111158107	A0A2Y9KCF4	A0A2Y9KPK4	Integrin alpha-V isoform X1; Belongs to the integrin alpha chain family.	Integrin beta; Belongs to the integrin beta chain family.	0.999
LOC111158088	LOC111144443	A0A2Y9KR71	A0A2Y9J0L6	Axin-2 isoform X1.	Secreted frizzled-related protein 1.	0.559
LOC111158088	LOC111144482	A0A2Y9KR71	A0A2Y9J1S2	Axin-2 isoform X1.	Secreted frizzled-related protein 1-like.	0.559