(21 nodes) Response to fluid shear stress network (Enhydra lutris)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

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co-expression

protein homology

Your Input:
	LOC111145612	ATP-binding cassette sub-family A member 1. (2261 aa)
	LOC111139244	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (812 aa)
	LOC111142427	Nuclear factor erythroid 2-related factor 2 isoform X1. (606 aa)
	LOC111141563	Tyrosine-protein kinase. (536 aa)
	LOC111142744	Mothers against decapentaplegic homolog. (426 aa)
	LOC111146777	Metastasis suppressor protein 1 isoform X1. (759 aa)
	LOC111146189	ATP-binding cassette sub-family A member 1-like. (167 aa)
	LOC111145667	ATP-binding cassette sub-family A member 2 isoform X1. (2461 aa)
	LOC111147852	Cbp/p300-interacting transactivator 2. (273 aa)
	LOC111145976	Argininosuccinate synthase. (412 aa)
	LOC111146646	Hyaluronan synthase 2. (552 aa)
	LOC111148445	Myocyte-specific enhancer factor 2C isoform X1. (483 aa)
	LOC111153274	Mothers against decapentaplegic homolog. (497 aa)
	LOC111153692	Protein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
	LOC111156389	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (594 aa)
	LOC111155864	Suppressor of cytokine signaling 5. (536 aa)
	LOC111156258	Polycystin-1 isoform X3. (4310 aa)
	LOC111156195	Polycystin-2. (970 aa)
	LOC111156491	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (406 aa)
	LOC111160084	LOW QUALITY PROTEIN: X-box-binding protein 1. (392 aa)
	LOC111156912	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (428 aa)

Your Current Organism:

Enhydra lutris

NCBI taxonomy Id: 391180
Other names: E. lutris kenyoni, Enhydra lutris kenyoni

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC111139244	LOC111141563	A0A2Y9IER2	A0A2Y9IRF1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Tyrosine-protein kinase.	0.438
LOC111139244	LOC111142427	A0A2Y9IER2	A0A2Y9IR61	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Nuclear factor erythroid 2-related factor 2 isoform X1.	0.914
LOC111139244	LOC111148445	A0A2Y9IER2	A0A2Y9JM62	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Myocyte-specific enhancer factor 2C isoform X1.	0.601
LOC111141563	LOC111139244	A0A2Y9IRF1	A0A2Y9IER2	Tyrosine-protein kinase.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.438
LOC111141563	LOC111153692	A0A2Y9IRF1	A0A2Y9KGR3	Tyrosine-protein kinase.	Protein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.980
LOC111142427	LOC111139244	A0A2Y9IR61	A0A2Y9IER2	Nuclear factor erythroid 2-related factor 2 isoform X1.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.914
LOC111142427	LOC111160084	A0A2Y9IR61	A0A2Y9KX26	Nuclear factor erythroid 2-related factor 2 isoform X1.	LOW QUALITY PROTEIN: X-box-binding protein 1.	0.408
LOC111142744	LOC111153274	A0A2Y9IT89	A0A2Y9K338	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.938
LOC111142744	LOC111156912	A0A2Y9IT89	A0A2Y9KX58	Mothers against decapentaplegic homolog.	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	0.429
LOC111145976	LOC111153692	A0A2Y9JGY0	A0A2Y9KGR3	Argininosuccinate synthase.	Protein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.613
LOC111148445	LOC111139244	A0A2Y9JM62	A0A2Y9IER2	Myocyte-specific enhancer factor 2C isoform X1.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.601
LOC111148445	LOC111153692	A0A2Y9JM62	A0A2Y9KGR3	Myocyte-specific enhancer factor 2C isoform X1.	Protein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.597
LOC111153274	LOC111142744	A0A2Y9K338	A0A2Y9IT89	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.938
LOC111153692	LOC111141563	A0A2Y9KGR3	A0A2Y9IRF1	Protein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tyrosine-protein kinase.	0.980
LOC111153692	LOC111145976	A0A2Y9KGR3	A0A2Y9JGY0	Protein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Argininosuccinate synthase.	0.613
LOC111153692	LOC111148445	A0A2Y9KGR3	A0A2Y9JM62	Protein-tyrosine kinase 2-beta isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Myocyte-specific enhancer factor 2C isoform X1.	0.597
LOC111156195	LOC111156258	A0A2Y9KTZ2	A0A2Y9KN08	Polycystin-2.	Polycystin-1 isoform X3.	0.997
LOC111156258	LOC111156195	A0A2Y9KN08	A0A2Y9KTZ2	Polycystin-1 isoform X3.	Polycystin-2.	0.997
LOC111156912	LOC111142744	A0A2Y9KX58	A0A2Y9IT89	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily.	Mothers against decapentaplegic homolog.	0.429
LOC111160084	LOC111142427	A0A2Y9KX26	A0A2Y9IR61	LOW QUALITY PROTEIN: X-box-binding protein 1.	Nuclear factor erythroid 2-related factor 2 isoform X1.	0.408